Fine-Tuning Of Kinesins And MAPs
Our Motivation
Our research focuses on the biology of proteins that functionalise the microtubule cytoskeleton - namely kinesins and microtubule associated proteins (MAPs). In particular, we try to understand how the biochemical and biophysical properties of a motor or a MAP translate into its in vivo function and how this is regulated. Hence, we follow a holistic experimental approach combining the in vitro characterisation of recombinant proteins on the single molecule level with a functional in vivo analysis of wild-type motors or their loss-of-function/gain-of-function variants. learn more
Who We Are
Dr. Hauke Drechsler
Independent Project Leader
Tel. +49 (351) 463 43014
Europe PubMed | ORCiD
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Nora Hartmann, M.Sc.
Technician
Tel. +49 (351) 463 43014
Our Partners In Science
Anne Straube, University of Warwick, UK | KIF15 in cell migration
Rolf Jessberger, TU Dresden, D | CENP-V in meiotic spindle assembly
Yixin Zhang, TU Dresden, D | synthetic microtubule associated proteins
We Are Generously Supported By
2019/07 - 2022/06
“Mechanistic and functional analysis of the multi-functional mitotic motor Kif15”
project grant; project number: 417890911 (view project at GEPRIS)
Deutsche Forschungsgemeinschaft (DFG), Bonn, Germany