20.12.2016; Vortrag
Seminar “Measurement Systems”
Biotec - Biotechnologisches Zentrum, TU Dresden
Thema: Brillouin microscopy – Optical characterization of the mechanical properties of tissues and cells
The mechanical properties of tissues and cells are often related to their biological function and can be an indicator of their status. Brillouin microscopy (BM) allows to non-invasively measure the stiffness of tissues and single cells by evaluating the spectrum of light which was inelastically scattered by the sample. By applying a spectrometer based on a virtually phased array (VIPA) interferometer it is possible to significantly reduce the measurement duration compared to previously used Fabry-Perot based spectrometers which enables the imaging of highly scattering samples such as living cells and tissues. The talk will focus on the challenges on how to setup a Brillouin microscope suitable for these samples.