PhD Projects Antigoni Stavridou - Regulation vs activation of immune responses to autoantigens Zuzana Marinicova - Presentation of insulin granule derived peptides on MHC I in Enterovirus-infected beta cells and type 1 diabetes (T1D) Denise Minerva Drotar - Human alpha cell physiology in the pathogenesis of type 2 diabetes Luka Jarc - Signaling pathways in the conversion of human pluripotent stem cells into functional beta-cells Margrit Kamel - Targeting G-protein-coupled receptors to enhance beta-cell function Bassam Aljani - Small RNA-Seq to reveal islet-miRNA modulation under stress- and transplantation conditions Carolin Heller - Macroencapsulation of pancreatic islets Iryna Pyrina - Co-stimulation in metabolic inflammation Salma Ahmed - Diverse signaling forms of Shh ligands and their effect on the canonical and non-canonical signaling pathways © Ulrich Lippke Nermeen Elagroudy - Inhibition of INDY (I’m Not Dead Yet) as a novel therapy for diabetes and NAFLD Fatma Betül Can Yakac - Lipid-protein interactions as basis for diabetes remission after bariatric surgery Norkhairin Yusuf - Discovering hybrid insulin peptide(s) and detecting reactivity by CD8+ T cells in Type 1 Diabetes Anica Kurzbach - Indy as a target for metabolic disease Emily Hanton - The Interaction Between B cells and Other Immune Cells in Type 1 Diabetes Pathogenesis Marius Mickunas - How does low dose IL-2 immunotherapy alter Regulatory T-cell Frequency, Phenotype and Function? Alice Santambrogio - Stem Cell Regulation in Endocrine Glands Ilona Berger - Signalling pathways in stem-like cells of the HPA axis during stress and metabolic changes Ana-Maria Cujba - Modelling monogenic diabetes using induced pluripotent stem cells (iPSCs) Theonie Demcollari - Investigating Insulin Promoter Factor 1 (Pdx1) stability for the generation of functional beta cells from adult progenitors and Induced Pluripotent Stem Cells (iPSCs) © Josephine Liers Josephine Liers - Combined Peptide Receptor-Targeted Cytotoxic/-Radionuclide Therapy for the Treatment of Metastatic Pheochromocytoma Learn more © Anna Strano Anna Strano - Leptin and leptin receptor signalling in the regulation of the hypothalamus-pituitary axis and in diabetic cardiomyopathy Learn more © S. Lämmle Ezzaldin Ahmed Alfar - Vici syndrome associated cardiomyopathy: Is it a form of diabetic cardiomyopathy? Learn more © Sarah Duin Sarah Duin - Utilizing bioprinting technologies for embedding of pancreatic islets in three-dimensional hydrogel constructs Learn more Project No. Title PhD student 1 Regulation vs activation of immune responses to autoantigens Antigoni Stavridou 2 Presentation of insulin granule derived peptides on MHC I in Enterovirus-infected beta cells and type 1 diabetes (T1D) Zuzana Marinicova 3 Human alpha cell physiology in the pathogenesis of type 2 diabetes Denise Minerva Drotar 4 Signaling pathways in the conversion of human pluripotent stem cells into functional beta-cells Luka Jarc 5 Targeting G-protein-coupled receptors to enhance beta-cell function Margrit Kamel 6 Small RNA-Seq to reveal islet-miRNA modulation under stress- and transplantation conditions Bassam Aljani 7 Macroencapsulation of pancreatic islets Carolin Heller 8 Co-stimulation in metabolic inflammation Iryna Pyrina 9 Diverse signaling forms of Shh ligands and their effect on the canonical and non-canonical signaling pathways Salma Ahmed 10 Inhibition of INDY (I’m Not Dead Yet) as a novel therapy for diabetes and NAFLD Nermeen Elagroudy 11 Lipid-protein interactions as basis for diabetes remission after bariatric surgery Fatma Betül Can Yakac 12 Discovering hybrid insulin peptide(s) and detecting reactivity by CD8+ T cells in Type 1 Diabetes Norkhairin Yusuf 13 Indy as a target for metabolic disease Anica Kurzbach 14 The Interaction Between B cells and Other Immune Cells in Type 1 Diabetes Pathogenesis Emily Hanton 15 How does low dose IL-2 immunotherapy alter Regulatory T-cell Frequency, Phenotype and Function? Marius Mickunas 16 Stem Cell Regulation in Endocrine Glands Alice Santambrogio 17 Signalling pathways in stem-like cells of the HPA axis during stress and metabolic changes Ilona Berger 18 Modelling monogenic diabetes using induced pluripotent stem cells (iPSCs) Ana-Maria Cujba 19 Investigating Insulin Promoter Factor 1 (Pdx1) stability for the generation of functional beta cells from adult progenitors and Induced Pluripotent Stem Cells (iPSCs) Theonie Demcollari 20 Combined Peptide Receptor-Targeted Cytotoxic/-Radionuclide Therapy for the Treatment of Metastatic Pheochromocytoma Josephine Liers 21 Leptin and leptin receptor signalling in the regulation of the hypothalamus-pituitary axis and in diabetic cardiomyopathy Anna Strano 22 Vici syndrome associated cardiomyopathy: Is it a form of diabetic cardiomyopathy? Ezzaldin Ahmed Alfar 23 Leader cells coordinate Beta-cell calcium dynamics in vivo Luis Delgadillo 24 Utilizing bioprinting technologies for embedding of pancreatic islets in three-dimensional hydrogel constructs Sarah Duin
