PhD Projects

Antigoni Stavridou - Regulation vs activation of immune responses to autoantigens

Zuzana Marinicova - Presentation of insulin granule derived peptides on MHC I in Enterovirus-infected beta cells and type 1 diabetes (T1D)

Denise Minerva Drotar - Human alpha cell physiology in the pathogenesis of type 2 diabetes

Luka Jarc - Signaling pathways in the conversion of human pluripotent stem cells into functional beta-cells

Margrit Kamel - Targeting G-protein-coupled receptors to enhance beta-cell function

Bassam Aljani - Small RNA-Seq to reveal islet-miRNA modulation under stress- and transplantation conditions

Carolin Heller - Macroencapsulation of pancreatic islets

Iryna Pyrina - Co-stimulation in metabolic inflammation

Salma Ahmed - Diverse signaling forms of Shh ligands and their effect on the canonical and non-canonical signaling pathways

Nermeen Elagroudy - Inhibition of INDY (I’m Not Dead Yet) as a novel therapy for diabetes and NAFLD

Fatma Betül Can Yakac - Lipid-protein interactions as basis for diabetes remission after bariatric surgery

Norkhairin Yusuf - Discovering hybrid insulin peptide(s) and detecting reactivity by CD8+ T cells in Type 1 Diabetes

Anica Kurzbach - Indy as a target for metabolic disease

Emily Hanton - The Interaction Between B cells and Other Immune Cells in Type 1 Diabetes Pathogenesis

Marius Mickunas - How does low dose IL-2 immunotherapy alter Regulatory T-cell Frequency, Phenotype and Function?

Alice Santambrogio - Stem Cell Regulation in Endocrine Glands

Ilona Berger - Signalling pathways in stem-like cells of the HPA axis during stress and metabolic changes

Ana-Maria Cujba - Modelling monogenic diabetes using induced pluripotent stem cells (iPSCs)

Theonie Demcollari - Investigating Insulin Promoter Factor 1 (Pdx1) stability for the generation of functional beta cells from adult progenitors and Induced Pluripotent Stem Cells (iPSCs)

Josephine Liers - Combined Peptide Receptor-Targeted Cytotoxic/-Radionuclide Therapy for the Treatment of Metastatic Pheochromocytoma Learn more

Anna Strano - Leptin and leptin receptor signalling in the regulation of the hypothalamus-pituitary axis and in diabetic cardiomyopathy Learn more

Ezzaldin Ahmed Alfar - Vici syndrome associated cardiomyopathy: Is it a form of diabetic cardiomyopathy? Learn more

Sarah Duin - Utilizing bioprinting technologies for embedding of pancreatic islets in three-dimensional hydrogel constructs Learn more

Project No.	Title	PhD student
1	Regulation vs activation of immune responses to autoantigens	Antigoni Stavridou
2	Presentation of insulin granule derived peptides on MHC I in Enterovirus-infected beta cells and type 1 diabetes (T1D)	Zuzana Marinicova
3	Human alpha cell physiology in the pathogenesis of type 2 diabetes	Denise Minerva Drotar
4	Signaling pathways in the conversion of human pluripotent stem cells into functional beta-cells	Luka Jarc
5	Targeting G-protein-coupled receptors to enhance beta-cell function	Margrit Kamel
6	Small RNA-Seq to reveal islet-miRNA modulation under stress- and transplantation conditions	Bassam Aljani
7	Macroencapsulation of pancreatic islets	Carolin Heller
8	Co-stimulation in metabolic inflammation	Iryna Pyrina
9	Diverse signaling forms of Shh ligands and their effect on the canonical and non-canonical signaling pathways	Salma Ahmed
10	Inhibition of INDY (I’m Not Dead Yet) as a novel therapy for diabetes and NAFLD	Nermeen Elagroudy
11	Lipid-protein interactions as basis for diabetes remission after bariatric surgery	Fatma Betül Can Yakac
12	Discovering hybrid insulin peptide(s) and detecting reactivity by CD8+ T cells in Type 1 Diabetes	Norkhairin Yusuf
13	Indy as a target for metabolic disease	Anica Kurzbach
14	The Interaction Between B cells and Other Immune Cells in Type 1 Diabetes Pathogenesis	Emily Hanton
15	How does low dose IL-2 immunotherapy alter Regulatory T-cell Frequency, Phenotype and Function?	Marius Mickunas
16	Stem Cell Regulation in Endocrine Glands	Alice Santambrogio
17	Signalling pathways in stem-like cells of the HPA axis during stress and metabolic changes	Ilona Berger
18	Modelling monogenic diabetes using induced pluripotent stem cells (iPSCs)	Ana-Maria Cujba
19	Investigating Insulin Promoter Factor 1 (Pdx1) stability for the generation of functional beta cells from adult progenitors and Induced Pluripotent Stem Cells (iPSCs)	Theonie Demcollari
20	Combined Peptide Receptor-Targeted Cytotoxic/-Radionuclide Therapy for the Treatment of Metastatic Pheochromocytoma	Josephine Liers
21	Leptin and leptin receptor signalling in the regulation of the hypothalamus-pituitary axis and in diabetic cardiomyopathy	Anna Strano
22	Vici syndrome associated cardiomyopathy: Is it a form of diabetic cardiomyopathy?	Ezzaldin Ahmed Alfar
23	Leader cells coordinate Beta-cell calcium dynamics in vivo	Luis Delgadillo
24	Utilizing bioprinting technologies for embedding of pancreatic islets in three-dimensional hydrogel constructs	Sarah Duin
25	Functional beta cell recovery in type 2 diabetes	Mariama Samuel Azmy Guirgus
26	Implementation of different signaling pathways for the full conversion of human pluripotent stem cells into functional β cells	Manuj Bandral
27	To elucidate the mechanism of delta-to-beta cell trans-differentiation in zebrafish pancreas	Prateek Chawla
28	Generation and characterization of pseudo-islets for beta-cell replacement	Hany Abdel Gawad Abdel Salam Abdel-Gawad
29	The role of ferroptotic cell death in diabetic nephropathy	Francesca Maremonti
30	Development of metabolic targeted approach to improve glucose-stimulated insulin synthesis and secretion in pancreatic beta-cells	Karthikeyan Mohanraj
31	Investigating development and impairments in pancreas using human embyronic stem cell-derived organoid models	Rashmiparvathi Keshara
32	Impact of phosphodiesterase 2 in diabetic cardiomyopathy	Eleder Cachorro Puente
33	T cell receptors for therapeutic application	Jing-Wun Li
34	Beta cell specific mechanisms of diabetes remission after bariatric surgery	Laurem Solís Moreno
35	INDY (I'm not dead, yet) as a target for metabolic disease	Anica Kurzbach
36	Identification and characterisation of a novel stern/progenitor population of the adrenal medulla	Alice Santambrogio
37	Signaling pathways in stem-like cells of the hypothalamic-pituitary-adrenal axis during stress and metabolic changes	Ikona Berger
48	Combined peptide receptor-targeted cytotoxic/radionuclide therapy for the treatment of metastatic pheocromocytoma	Josephine Liers
39	In vivo characterization of of Ca²⁺dynamics in pancreatic β-cells of Zebrafish	Luis Fernando Delgadillo Silva
40	Regulated necrosis of adrenocortical carcinomas	Alexia Belavgeni
41	Prevention of glucocorticoid-induced obesity through selective activation of the sympathetic nervous system	Manuel Gado

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