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Zentrum für Informationsdienste und Hochleistungsrechnen

12.12.2018
„The invasion speed of cell migration models with realistic cell cycle time distributions“

Zeit 11:30 Uhr
Ort APB 1096
Veranstalter Zentrum für Informationsdienste und Hochleistungsrechnen
Informationen Ralph Müller-Pfefferkorn
Website: https://tu-dresden.de/zih/

Referent/in: Enrico Gavagnin (University of Bath)

Cell proliferation is typically incorporated into stochastic mathematical models of cell migration by assuming that cell divisions occur after an exponentially distributed waiting time. Experimental observations, however, show that this assumption is often far from the real cell cycle time distribution (CCTD). In this talk I will  investigate the connection between the CCTD and the speed of the collective cell invasion. I will present a series of stochastic and deterministic age-structured models which can be used to explore this connection from an analytical perspective. The results allow us to determine the range of possible invasion speeds in terms of the average cell proliferation time. Finally, I will discuss potential medical applications of these models to melanoma drug treatment optimisation and other extensions.

Stand: 04.12.2018 18:32
Autor: Universitätsmarketing

Kontakt

Redaktion:
Monique Rust
Tel.: +49 351 463-32397
Fax:  +49 351 463-37135
monique.rust@tu-dresden.de

Sitz:
Nöthnitzer Str. 43,
Zi. 205


Internetaufbereitung:
Medienzentrum
mz-nutzerberatung@tu-dresden.de