Angelika Buske-Kirschbaum

adjunct professor
NameMs Prof. Dr. Angelika Buske-Kirschbaum
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Research interests
Psychoneuroimmunology (stress and immune function)
Psychodermatology (the role of psychosocial stress in the development, chronification and exacerbation of inflammatory skin disease)
Developmental psychobiology (the effect of stress exposure during the life span and its (differential) effect on health and disease)
2009 |
Habilitation in Psychology Title of the habilitaion: stress as a Triffering Factor in Atopic Skin Disease – Protential Mechanisms and Implications |
since 2004 |
Assistant professor at the Dept. of Biopsychology, Technical University of Dresden, Germany |
1994 – 2003 |
Assistant professor at the Dept. of Psychobiology, University of Trier, Germany |
1994 |
Doctorate (Dr. rer. nat.), „summa cum laude“; University of Trier; title of the doctoral thesis: “Classical conditioning of immune function in humans” |
1992 – 1993 |
Postdoctoral education at the University of Rochester, NY. USA, Dept. of Neuroanatomy and Neurobiology. Supervisor: D.L. Felten, MD, PhD |
1989 – 1991 |
Teaching assistent at the University of Trier; Dept. of Clinical and Physiological Psychology: Research Activities: Classical conditioning of the immune system; stress and immune function. Supervisor: D.H. Hellhammer, PhD |
1983 – 1989 |
University study (psychology), Wilhelms University Münster/Westfalen |
1989 |
Diploma in psychology |
10.1997 |
Poster Award of the European Society for Dermatology and Psychiatry |
02.1995 |
Dissertation Award of the German Society of Behavioral Medicine |
06.1990 |
Poster Award of the German Society for Medical Psychology |
09.2012 - 12.2016 | German Research Foundation (DFG): Psychoimmunologische und psychoendokrine Prozesse bei der Komorbidität von atopischem Ekzem und ADHS. |
01.2000 – 12.2002 |
German Research Foundation (DFG): Altered responsiveness of the hypothalamus-pituitary-adrenal (HPA) axis - an etiologically and pathologically relevant factor in TH2- and TH1-mediated chronic inflammatory disorders? |
01.1997 – 12.1999 |
German Research Foundation (DFG): The hypothalamus-pituitary-adrenal (HPA) axis - a protective factor in atopic disorders? |
09.1995 – 08.1997 |
German Research Foundation (DFG): Adrenergic mechanisms in classically conditioned modulation of natural killer (NK) cell activity in humans. |
2020
Rothe, N., Schulze, J., Kirschbaum, C., Buske-Kirschbaum, A., Penz, M., Wekenborg, M.K., Walther, A. (2020). Sleep disturbances in major depressive and burnout syndrome: A longitudinal analysis. Psychiatry Research. April 2020, 112868. doi: 10.1016/j.psychres.2020.112868
2019
Buske-Kirschbaum, A., Trikojat, K., Tesch, F., Schmitt, J., Roessner, V., Luksch, H., Rösen-Wolff, A., Plessow, F. (2019). Altered hypothalamus-pituitary-adrenal axis function: A relevant factor in the comorbidity of atopic eczema and attention deficit/hyperactivity disorder? Psychoneuroendocrinology 2019 Jul;105:178-186. doi: 10.1016/j.psyneuen.2018.12.005.
2018
Baran, W., Oehrl, S., Ahmad, F., Döbel, T., Alt, C., Buske-Kirschbaum, A., Schmitz, M., Schäkel, K. (2018). Phenotype, Function, and Mobilization of 6-Sulfo LacNAc-Expressing Monocytes in Atopic Dermatitis. Front Immunol. 2018 Jun 21;9:1352. doi: 10.3389/fimmu.2018.01352. [eCollection 2018].
Penz, M., Kirschbaum, C., Buske-Kirschbaum, A., Wekenborg, M.K,, Miller, R. (2018) Stressful life events predict one-year change of leukocyte composition in peripheral blood. Psychoneuroendocrinology. 2018 Aug;94:17-24. doi: 10.1016/j.psyneuen.2018.05.006. [Epub 2018 May 4].
Schmitt, J., Buske-Kirschbaum, A., Tesch, F., Trikojat, K., Stephan, V., Abraham, S., Bauer, A., Nemat, K., Plessow, F., Roessner, V. (2018). Increased attention-deficit/hyperactivity symptoms in atopic dermatitis are associated with history of antihistamine use. Allergy. 2018 Mar;73(3):615-626. doi: 10.1111/all.13326. [Epub 2017 Nov 20].
2017
Trikojat, K., Buske-Kirschbaum, A., Plessow, F., Schmitt, J., Fischer, R. (2017) Memory and multitasking performance during acute allergic inflammation in seasonal allergic rhinitis. Clin Exp Allergy. 2017 Apr;47(4):479-487.doi:org/10.1111/cea.12893
Trikojat, K., Luksch, H., Rösen-Wolff, A., Plessow, F., Schmitt, J., Buske-Kirschbaum, A. (2017) "Allergic mood" - Depressive and anxiety symptoms in patients with seasonal allergic rhinitis (SAR) and their association to inflammatory, endocrine, and allergic markers. Brain Behav Immun. 2017 Oct;65:202-209. doi: org/10.1016/j.bbi.2017.05.005
2015
Buske-Kirschbaum, A., Roessner, V., Trikojat, K., Plessow, F., Schmitt, J. (2015). Atopisches Ekzem (AE) und Aufmerksamkeitsdefizit/ Hyperaktivitätsstörung – ein Zusammenhang? Haut
Trikojat, K., Buske-Kirschbaum, A., Schmitt, J., Plessow, F. (2015). Altered performance in attention tasks in patients with seasonal allergic rhinitis: seasonal dependency and association with disease characteristics. Psychological Medicine, 1-11. doi: 10.1017/S0033291714002384
Trikojat, K., Schmitt, J., Roessner, V., Plessow, F., Buske-Kirschbaum, A. (2015). Komorbidität von Neurodermitis und Aufmerksamkeits Defizit/Hyperaktivitäts-Störung. Mögliche psychoneuroimmunologische Ursachen und aktuelle Forschungsfragen. Allergologie
2013
Buske-Kirschbaum, A., Schmitt, J., Plessow, F., Romanos, M., Weidinger, S., & Roessner, V. (2013). Psychoendocrine and psychoneuroimmunological mechanisms in the comorbidity of atopic eczema and attention deficit/hyperactivity disorder. Psychoneuroendocrinology, 38(1), 12-23. doi: 10.1016/j.psyneuen.2012.09.017
Schmitt, J., Buske-Kirschbaum, A., Trikojat, K., Roessner, V., Romanos, M. (2013). Neurodermitis als Risikofaktor für die Entstehung einer Aufmerksamkeits-Defizit/Hyperaktivitäts-Störung – Epidemiologische Evidenz und mögliche Mechanismen. Pädiatrische Allergologie; 16 (2):17-21.
2012
Pluess, M., Wurmser, H., Buske-Kirschbaum, A., Papousek, M., Pirke, K. M., Hellhammer, D., Bolten, M. (2012). Positive life events predict salivary cortisol in pregnant women. Psychoneuroendocrinology. 2012 Aug;37(8):1336-40. doi: 10.1016/j.psyneuen.2012.01.006. [Epub 2012 Feb 5].
2011
Bolten, M. I., Wurmser, H., Buske-Kirschbaum, A., Papousek, M., Pirke, K. M., Hellhammer, D. (2011). Cortisol levels in pregnancy as a psychobiological predictor for birth weight. Arch Womens Ment Health. 2011 Feb;14(1):33-41. doi: 10.1007/s00737-010-0183-1. [Epub 2010 Sep 25].
Romanos, M., Buske-Kirschbaum, A., Folster-Holst, R., Gerlach, M., Weidinger, S., Schmitt, J. (2011). Itches and scratches - is there a link between eczema, ADHD, sleep disruption and food hypersensitivity? Allergy. 2011 Nov;66(11):1407-9. doi: 10.1111/j.1398-9995.2011.02705.x.
2010
Buske-Kirschbaum, A., Ebrecht, M., Hellhammer, D.H. (2010). Blunted HPA axis responsiveness to stress in atopic patients is associated with the acuity and severeness of allergic inflammation. Brain Behav Immun. 2010 Nov;24(8):1347-53. doi: 10.1016/j.bbi.2010.06.013. [Epub 2010 Jul 13].
Schmitt, J., Buske-Kirschbaum, A., Roessner, V. (2010). Is atopic disease a risk factor for attention- deficit/hyperactivity disorder? A systematic review. Allergy. 2010 Dec;65(12):1506-24. doi: 10.1111/j.1398-9995.2010.02449.x. [Epub 2010 Aug 17]. Review.
2009
Buske-Kirschbaum, A. (2009). Cortisol responses in allergic children: interaction with the immune response. Neuroimmunomodulation. 2009;16(5):325-32. doi: 10.1159/000216190. [Epub 2009 Jun 29]. Review.
2008
Buske-Kirschbaum, A. (2008). Treating the parents to heal the child? Brain Behav Immun. 2008 May;22(4):431-2. doi: 10.1016/j.bbi.2008.01.003. [Epub 2008 Feb 21]. Review.
Buske-Kirschbaum, A., Ebrecht, M., Kern, S., Gierens, A., Hellhammer, D.H. (2008). Personality characteristics in chronic and non-chronic conditions. Brain Behav Immun. 2008 Jul;22(5):762-8. doi: 10.1016/j.bbi.2007.12.002. [Epub 2008 Jan 31].
2007
Buske-Kirschbaum, A., Kern, S., Ebrecth, M., Hellhammer, D.H. (2007). Altered distribution of leukocyte subsets and cytokine levels in response to acute psychosocial stress in patients with psoriasis vulgaris. Brain Behav Immun. 2007 Jan;21(1):92-9. doi: 10.1016/j.bbi.2006.03.006. [Epub 2006 May 22].
Buske-Kirschbaum, A., Krieger, S., Wilkes, C., Rauh, W., Weiss, S., Hellhammer, D.H. (2007). Hypothalamic-pituitary-adrenal-axsi function and the cellular immune response in former preterm children. J Clin Endocrinol Metab. 2007 Sep;92(9):3429-35. doi: 10.1210/jc.2006-2223. [Epub 2007 Jun 12].
Buske-Kirschbaum, A. Endocrine and Immune Responses to Stress in Chronic Inflammatory Skin Disorder (Atopic Dermatitis) (2007). In Robert Ader (Ed.). Psychoneuroimmunology. 4th Edition, New York and Oxford: Elsevier.
Buske-Kirschbaum, A. Stress and psoriasis. In G. Fink (ed). Encyclopedia of Stress (2nd edition). Elsevier Science, Oxford.
Buske-Kirschbaum, A., Hellhammer, D.H. (2007). Pathophysiologie unter Betrachtung von endokrinoimmunen Interaktionen bei der atopischen Dermatitis. In: Straub, R. (Hg.), Lehrbuch der klinischen Pathophysiologie komplexer chronischer Erkrankungen. Band 2: Spezielle Pathophysiologie. Göttingen: Vandenhoeck & Ruprecht, S. 132-136.
2006
Buske-Kirschbaum A., Ebrecht, M., Kern, S., Hellhammer, D.H. (2006) Endocrine stress responses in TH1-mediated chronic inflammatory skin desease (psoriasis vulgaris) – do they parallel stress-inducedendocrine changes in TH2-mediated inflammatory dermatoses (atopic dermatitis)? Psychoneuroendocrinology. 2006 May;31(4):439-46. doi: 10.1016/j.psyneuen.2005.10.006. [Epub 2005 Dec 13].
Wurmser, H., Rieger, M., Domogalla, C., Kahnt, A., Buchwald, J., Kowatsch, M., Kuehnert, N., Buske-Kirschbaum, A., Papousek, M., Pirke, K.M., von Voss, H. (2006). Association between life stress during pregnancy and infant crying in the first six months postpartum: A prospective longitudinal study. Early Human Development. 2006 May;82(5):341-9. doi: 10.1016/j.earlhumdev.2005.09.016. [Epub 2006 Feb 10].
2004
Buske-Kirschbaum, A., Fischbach, S., Rauh, W., Hanker, J., Hellhammer, D. (2004). Increased responsiveness of the hypothalamus-pituitary-adrenal (HPA) axis to stress in newborns with atopic disposition. Psychoneuroendocrinology. 2004 Jul;29(6):705-11. doi: 10.1016/S0306-4530(03)00100-8
Kudielka, B.M., Buske-Kirschbaum, A., Hellhammer, D. H., Kirschbaum, C. (2004). Differential heart rate reactivity and recovery after psychosocial stress (TSST) in healthy children, younger adults, and elderly adults: the impact of age and gender. Int J Behav Med, 11(2), 116-121. doi:10.1207/s15327558ijbm1102_8
Kudielka, B.M., Buske-Kirschbaum, A., Hellhammer, D. H., Kirschbaum, C. (2004). HPA axis responses to laboratory psychosocial stress in healthy elderly adults, younger adults, and children: impact of age and gender. Psychoneuroendocrinology. 2004 Jan;29(1):83-98. doi: 10.1016/S0306-4530(02)00146-4.
Rieger, M., Pirke, K.M., Buske-Kirschbaum, A., Wurmser, H., Papousek, M., Hellhammer, D.H. (2004). Influence of stress during pregnancy on HPA activity and neonatal behavior. Ann N Y Acad Sci. 2004 Dec;1032:228-30. doi: 10.1196/annals.1314.026.
2003
Buske-Kirschbaum, A., Hellhammer, D. H. (2003). Endocrine and immune responses to stress in chronic inflammatory skin disorders. Ann N Y Acad Sci. 2003 May;992:231-40. Review. doi: 10.1111/j.1749-6632.2003.tb03153.x.
Buske-Kirschbaum, A., von Auer, K., Krieger, S., Weiss, S., Rauh, W., Hellhammer, D.H. (2003). Blunted cortisol responses to psychosocial stress in asthmatic children: a general feature of atopic disease? Psychosom Med. 2003 Sep-Oct;65(5):806-10. doi: 10.1097/01.PSY.0000095916.25975.4F
Buske-Kirschbaum, A., Grota, L., Kirschbaum, C., Bienen, T., Moynihan, J., Ader, R., Blair, L., Hellhammer, D.H. & Felten, D.L. (1996). Conditioned increases in peripheral blood mononuclear cell (PBMC) number and corticosterone secretion in the rat. Pharmacology, Biochemistry and Behavior, 55, 27-32.
Buske-Kirschbaum, A., Kirschbaum, C. & Hellhammer, D. H. (1994). Conditioned modulation of NK cells in humans: Alteration of cell activity and cell number by conditioning protocols. Psychologische Berichte, 36, 100-111.
Buske-Kirschbaum, A., Kirschbaum, C., Jabaij, L., Stierle, H. & Hellhammer, D. H. (1994). Conditioned manipulation of natural killer (NK) cells in humans using a discriminative learning protocol. Biological Psychology, 38, 143-155.
Buske-Kirschbaum, A., Kirschbaum, C., Stierle, H., Lehnert, H. & Hellhammer, D.H. (1992). Classical conditioning of natural killer cell activity (NKCA) in humans. Psychosomatic Medicine, 54, 123-132.
Kirschbaum, C., Jabaaij, L., Buske-Kirschbaum, A., Hennig, J., Blom, M., Dorst, K., Bauch, J., DiPauli, R., Schmitz, G., Ballieux, R. & Hellhammer, D.H. (1992).
Conditioning of drug-induced immunomodulation in human volunteers - a European collaborative study. British Journal of Clinical Psychology, 31, 459-472.
Buske-Kirschbaum, A., Kirschbaum, C. & Hellhammer, D.H. (1991). Klassische Konditionierung der Immunreaktivität. In E. Jäger (Hrsg.), Die HIV-Erkrankung - Medizinische und psychosoziale Aspekte zu Beginn der 90er Jahre (S. 287-290). Landsberg/Lech: Ecomed.
Buske-Kirschbaum, A., Kirschbaum, C. & Hellhammer, D. H. (1990). Die Erlernbarkeit immunologischer Reaktionen. Deutsche AIDS-Stiftung "Positiv leben" (Hrsg.), Aids und Psyche - Zum Einfluss von Psyche und Immunsystem auf den Verlauf der HIV-Infektion. Berlin: Edition Sigma.
Buske-Kirschbaum, A., Kirschbaum, C. & Hellhammer, D. H. (1990). Psychoneuroimmunologie. R. Schwarzer (Hrsg.), Gesundheitspsychologie. (S. 35-43). Göttingen: Hogrefe.
Buske-Kirschbaum, A., Jobst, S., & Hellhammer, D. H. (1998). Altered reactivity of the hypothalamus-pituitary-adrenal axis in patients with atopic dermatitis: pathologic factor or symptom? Ann N Y Acad Sci, 840, 747-754
Augustin, M., Zschocke, I., Godau, N., Buske-Kirschbaum, A., Peschen, M., Sommer, B., & Sattler, G. (1999). Skin surgery under local anesthesia leads to stress-induced alterations of psychological, physical, and immune functions. Dermatologic Surgery, 25(11), 868-871
Buske-Kirschbaum, A., Geiben, A., & Hellhammer, D. (2001). Psychobiological aspects of atopic dermatitis: an overview. Psychother Psychosom, 70(1), 6-16
Buske-Kirschbaum, A., Geiben, A., Wermke, C., Pirke, K. M., & Hellhammer, D. (2001). Preliminary evidence for Herpes labialis recurrence following experimentally induced disgust. Psychother Psychosom, 70(2), 86-91
Buske-Kirschbaum, A., Geiben, A., Hollig, H., Morschhauser, E., & Hellhammer, D. (2002). Altered responsiveness of the hypothalamus-pituitary-adrenal axis and the sympathetic adrenomedullary system to stress in patients with atopic dermatitis. J Clin Endocrinol Metab, 87(9), 4245-4251
Buske-Kirschbaum, A., Gierens, A., Hollig, H., & Hellhammer, D. H. (2002). Stress-induced immunomodulation is altered in patients with atopic dermatitis. Journal of Neuroimmunol, 129(1-2), 161-167.
Buske-Kirschbaum, A., von Auer, K., Krieger, S., Weis, S., Rauh, W., & Hellhammer, D. (2003). Blunted cortisol responses to psychosocial stress in asthmatic children: a general feature of atopic disease? Psychosom Med, 65(5), 806-810
Exton, M. S., von Auer, A. K., Buske-Kirschbaum, A., Stockhorst, U., Gobel, U., & Schedlowski, M. (2000). Pavlovian conditioning of immune function: animal investigation and the challenge of human application. Behavioral Brain Research, 110(1-2), 129-141.
Buske-Kirschbaum, A., Jobst, S., Wustmans, A., Kirschbaum, C., Rauh, W. & Hellhammer, D.H. (1997). Attenuated free cortisol response to psychosocial stress in children with atopic dermatitis. Psychosomatic Medicine, 59, 419-426.
Buske-Kirschbaum, A., Kirschbaum, C. & Hellhammer, D.H. (1997). Psychoneuroimmunologie - Konzepte und neuropsychologische Implikationen. In E. Kasten, M. Kreutz, B. A. Sabel (Hrsg.), Neuropsychologie in Forschung und Praxis. Jahrbuch der Medizinischen Psychologie 12. Göttingen: Hogrefe (S. 79-98).
Pruessner, J. C., Wolf, O. T., Hellhammer, D. H., Buske-Kirschbaum, A., von Auer, K., Jobst, S., Kaspers, F. & Kirschbaum, C. (1997). Free cortisol levels after awakening: A reliable biological marker for the assessment of adrenocortical activity. Life Sciences 61(26), 2539-2549.
Prüßner, J.C., Wolf, O.T., von Auer, K., Jobst, S., Kaspers, F., Buske-Kirschbaum, A., Hellhammer, D.H. & Kirschbaum, C. (1997). The cortisol response to awakening: consistency, reliability, and individual differences. Life Sciences 61, 2539-2549.
Ebrecht, M., Buske-Kirschbaum, A., Hellhammer, D.H., Kern, S., Rohleder, N., Walker, B.R. & Kirschbaum, C. (2000). Tissue specificity of glucocorticoid sensitivity in healthy adults. Journal of Clinical Endocrinology and Metabolism, 85, 3733-3739.
Buske-Kirschbaum, A., Ebrecht, M., Kern, S., Höllig, H., Gierens, A. & Hellhammer D.H. (2004). Personality characteristics and their association with biological stress responses in patients with atopic dermatitis. Dermatology and Psychosomatics, 5, 12-16.
Buske-Kirschbaum, A., Fischbach, S., Rauh, W., Hanker, J. & Hellhammer, D.H. (2004). Increased responsiveness of the hypothalamus-pituitary-adrenal (HPA) axis to stress in newborns with atopic disposition. Psychoneuroendocrinology, 29, 705-711.
Kudielka, B.M., Buske-Kirschbaum, A., Hellhammer, D.H. & Kirschbaum, C. (2004). HPA axis responses to laboratory psychosocial stress in healthy elderly adults, younger adults, and children: impact of age and gender. Psychoneuroendocrinology, 29, 83-98.
Kudielka, B.M., Buske-Kirschbaum, A., Hellhammer, D.H. & Kirschbaum, C. Differential heart rate reactivity and recovery after psychosocial stress (TSST) in healthy children, younger adults, and elderly adults: The impact of age and gender. International Journal of Behavioral Medicine, 11, 116-121.
Rieger, M., Pirke, K.M., Buske-Kirschbaum, A., Wurmser, H., Papousek, M. & Hellhammer, D.H. (2004). Influence of stress during pregnancy on HPA activity and neonatal behavior. Annals of the New York Academy of Sciences, 1032, 228-230.