Publikationen

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Alle Publikationen in Fachzeitschriften 

• Renn M, Bartok E, Zillinger T, Hartmann G, Behrendt R

  Animal models of SARS-CoV-2 and COVID-19 for the development of prophylactic and therapeutic interventions

  Pharmacol Ther. 2021 in press https://doi.org/10.1016/j.pharmthera.2021.107931

• Muhandes L, Chapsa M, Pippel M, Behrendt R, Ge Y, Dahl A, Yi B, Dalpke A, Winkler S, Hiller M, Boutin S, Beissert S, Jessberger R, Fallon PG, Roers A.

  Low threshold for cutaneous allergen sensitization but no spontaneous dermatitis or atopy in filaggrin-deficient mice.

  J Invest Dermatol. 2021 Apr 21;  doi: 10.1016/j.jid.2021.02.763.

• Prabakaran T, Troldborg A, Kumpunya S, Alee I, Marinković E, Windross SJ, Nandakumar R, Narita R, Zhang BC, Carstensen M, Vejvisithsakul P, Marqvorsen MHS, Iversen MB, Holm CK, Østergaard LJ, Pedersen FS, Pisitkun T, Behrendt R*, Pisitkun P*, Paludan SR*.

  A STING antagonist modulating the interaction with STIM1 blocks ER-to-Golgi trafficking and inhibits lupus pathology.

  EBioMedicine. 2021 Apr 1;66:103314. doi: 10.1016/j.ebiom.2021.103314.

• Reinke S, Linge M, Diebner HH, Luksch H, Glage S, Gocht A, Robertson AAB, Cooper MA, Hofmann SR, Naumann R, Sarov M, Behrendt R, Roers A, Pessler F, Roesler J, Rösen-Wolff A, Winkler S. 
  Non-canonical Caspase-1 Signaling Drives RIP2-Dependent and TNF-α-Mediated Inflammation In Vivo.
  Cell Rep. 2020 Feb 25;30(8):2501-2511.e5. doi: 10.1016/j.celrep.2020.01.090. 
• Schulz A, Gorodetska I, Behrendt R, Fuessel S, Erdmann K, Foerster S, Datta K, Mayr T, Dubrovska A, Muders MH.
  Linking NRP2 With EMT and Chemoradioresistance in Bladder Cancer.
  Front Oncol. 2020 Jan 21;9:1461. doi: 10.3389/fonc.2019.01461. eCollection 2019.  
• Lindel F, Dodt CR, Weidner N, Noll M, Bergemann F, Behrendt R, Fischer S, Dietrich J, Cartellieri M, Hamann MV, Lindemann D.
  TraFo-CRISPR: Enhanced Genome Engineering by Transient Foamy Virus Vector-Mediated Delivery of CRISPR/Cas9 Components.
  Mol Ther Nucleic Acids. 2019 Dec 6;18:708-726. doi: 10.1016/j.omtn.2019.10.006.  
• Kessel F, Steglich A, Tschongov T, Gembardt F, Ruhnke L, Stumpf J, Behrendt R, Cohrs C, Kopaliani I, Todorov V, Gerlach M, Hugo C.
  New automatic quantification method of immunofluorescence and histochemistry in whole histological sections.
  Cell Signal. 2019 Oct;62:109335. doi: 10.1016/j.cellsig.2019.05.020. 

• Hiller B, Hoppe A, Haase C, Hiller C, Schubert N, Müller W, Reijns MAM, Jackson AP, Kunkel TA, Wenzel J, Behrendt R*, Roers A*.
  Ribonucleotide excision repair is essential to prevent squamous cell carcinoma of the skin.
  Cancer Res. 2018 Aug 28. pii: canres.1099.2018. doi: 10.1158/0008-5472.CAN-18-1099.

• Haag SM, Gulen MF, Reymond L, Gibelin A, Abrami L, Decout A, Heymann M, Goot FGV, Turcatti G, Behrendt R, Ablasser A.

  Targeting STING with covalent small-molecule inhibitors.

  Nature. 2018 Jul 4. doi: 10.1038/s41586-018-0287-8.

• Ghouse SM, Polikarpova A, Muhandes L, Dudeck J, Tantcheva-Poór I, Hartmann K, Lesche M, Dahl A, Eming S, Müller W, Behrendt R, Roers A.

  Although Abundant in Tumor Tissue, Mast Cells Have No Effect on Immunological Micro-milieu or Growth of HPV-Induced or Transplanted Tumors.

  Cell Rep. 2018 Jan 2;22(1):27-35.

• Achleitner M., Kleefisch M., Hennig A., Peschke K., Polikarpova A., Oertel R., Gabriel B., Schulze L., Lindeman D., Gerbaulet A., Fiebig U., Lee-Kirsch M.A., Roers A., Behrendt R.
  Lack of Trex1 causes systemic autoimmunity despite the presence of antiretroviral drugs
  J Immunol. 2017 Oct 1;199(7):2261-2269.
• Morcos MNF, Schoedel KB, Hoppe A, Behrendt R, Basak O, Clevers HC, Roers A, Gerbaulet A.
  SCA-1 Expression Level Identifies Quiescent Hematopoietic Stem and Progenitor Cells.
  Stem Cell Reports. 2017 Jun 6;8(6):1472-1478. doi: 10.1016/j.stemcr.2017.04.012.
• Weidemann RR, Behrendt R, Schoedel KB, Müller W, Roers A, Gerbaulet A.
  Constitutive Kit activity triggers B-cell acute lymphoblastic leukemia-like disease in mice.
  Exp Hematol. 2017 Jan;45:45-55.e6. doi: 10.1016/j.exphem.2016.09.005.
• Peschke K, Achleitner M, Frenzel K, Gerbaulet A, Ada SR, Zeller N, Lienenklaus S, Lesche M, Poulet C, Naumann R, Dahl A, Ravens U, Günther C, Müller W, Knobeloch KP, Prinz M, Roers A, Behrendt R
  Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity.
  J Immunol. 2016 Sep 15;197(6):2157-66. doi: 10.4049/jimmunol.1600722.
• Kunz S, Dolch A, Surianarayanan S, Dorn B, Bewersdorff M, Alessandrini F, Behrendt R, Karp CL, Muller W, Martin SF, Roers A, Jakob T.
  T cell derived IL-10 is dispensable for tolerance induction in a murine model of allergic airway inflammation.
  Eur J Immunol. 2016 Aug;46(8):2018-27. doi: 10.1002/eji.201646319.
• Wittmann S, Behrendt R, Eissmann K, Volkmann B, Thomas D, Ebert T, Cribier A, Benkirane M, Hornung V, Bouzas NF, Gramberg T.
  Phosphorylation of murine SAMHD1 regulates its antiretroviral activity.
  Retrovirology. 2015 Dec 15;12:103. doi:10.1186/s12977-015-0229-6.
• Peschke K, Weitzmann A, Heger K, Behrendt R, Schubert N, Scholten J, Voehringer D, Hartmann K, Dudeck A, Schmidt-Supprian M, Roers A.
  IκB kinase 2 is essential for IgE-induced mast cell de novo cytokine production but not for degranulation.
  Cell Rep. 2014 Sep 11;8(5):1300-7. doi:10.1016/j.celrep.2014.07.046.
• Ablasser A, Hemmerling I, Schmid-Burgk JL, Behrendt R, Roers A, Hornung V.
  TREX1 deficiency triggers cell-autonomous immunity in a cGAS-dependent manner.
  J Immunol. 2014 Jun 15;192(12):5993-7. doi: 10.4049/jimmunol.1400737.
• Peschke K, Friebe F, Zimmermann N, Wahlicht T, Schumann T, Achleitner M, Berndt N, Luksch H, Behrendt R, Lee-Kirsch MA, Roers A, Günther C.
  Deregulated type I IFN response in TREX1-associated familial chilblain lupus.
  J Invest Dermatol. 2014 May;134(5):1456-9. doi: 10.1038/jid.2013.496.
• Behrendt R, Roers A.
  Mouse models for Aicardi-Goutières syndrome provide clues to the molecular pathogenesis of systemic autoimmunity.
  Clin Exp Immunol. 2014 Jan;175(1):9-16. doi: 10.1111/cei.12147. Review.
• Richter K, Perriard G, Behrendt R, Schwendener RA, Sexl V, Dunn R, Kamanaka M, Flavell RA, Roers A, Oxenius A.
  Macrophage and T cell produced IL-10 promotes viral chronicity.
  PLoS Pathog. 2013;9(11):e1003735. doi: 10.1371/journal.ppat.1003735.
• Behrendt R*, Schumann T*, Gerbaulet A, Nguyen LA, Schubert N, Alexopoulou D, Berka U, Lienenklaus S, Peschke K, Gibbert K, Wittmann S, Lindemann D, Weiss S, Dahl A, Naumann R, Dittmer U, Kim B, Mueller W, Gramberg T, Roers A.
  Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response.
  Cell Rep. 2013 Aug 29;4(4):689-96. doi: 10.1016/j.celrep.2013.07.037.
• Hiller B, Achleitner M, Glage S, Naumann R, Behrendt R*, Roers A*.
  Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity.
  J Exp Med. 2012 Jul 30;209(8):1419-26. doi: 10.1084/jem.20120876.
• Behrendt R, Fiebig U, Kurth R, Denner J.
  Induction of antibodies binding to the membrane proximal external region of gp36 of HIV-2.
  Intervirology. 2012 ;55(3):252-6. doi: 10.1159/000324483.
• Behrendt R, Fiebig U, Norley S, Gürtler L, Kurth R, Denner J.
  A neutralization assay for HIV-2 based on measurement of provirus integration by duplex real-time PCR.
  J Virol Methods. 2009 Jul;159(1):40-6. doi: 10.1016/j.jviromet.2009.02.024.