Dresden Translational Oncology Seminar, Prof. Florent Ginhoux, Gustave Roussy, Cancer Campus, Paris

The role of macrophages in disease pathology – Join the DTOS on 12.10.2022 12 am CET

The Ginhoux lab is focusing on the ontogeny and differentiation of macrophages and dendritic cells and their roles in tissue homeostasis, immunity and disease pathology. On October 12th, Florent Ginhoux will provide insights into his translational research at the virtual Dresden Translational Oncology Seminar speaking about Tumor Macrophage Heterogeneity.

Florent graduated in Biochemistry from the University Pierre et Marie CURIE (UPMC), Paris VI, obtained a Masters degree in Immunology from the Pasteur Institute in 2000 and his PhD in 2004 from UPMC, Paris VI. As a postdoctoral fellow, he joined the Laboratory of Miriam Merad in the Mount Sinai School of Medicine (MSSM), New York, where he studied the ontogeny and the homeostasis of cutaneous dendritic cell populations, with a strong focus on Langerhans cells and Microglia. In 2008, he became an Assistant Professor in the Department of Gene and Cell Medicine, MSSM and member of the Immunology Institute of MSSM. He joined the Singapore Immunology Network (SIgN), A*STAR in May 2009 as a Junior Principal Investigator and became Senior Principal Investigator in 2014. He joined the EMBO Young Investigator (YIP) program in 2013 and is a Web of Science Highly Cited Researcher since 2016. Florent is also an Adjunct Visiting Associate Professor in the Shanghai Immunology Institute, Jiao Tong University, in Shanghai, China since 2015 and Adjunct Associate Professor in the Translational Immunology Institute, SingHealth and Duke NUS, Singapore since 2016. He is now a Laboratory Director in Gustave Roussy focusing on pediatric cancers and the role of myeloid cells in tumor progression and became an EMBO member in 2022.

Dendritic cells (DCs), monocytes and macrophages play crucial and distinct roles in tissue homeostasis and immunity, but also contribute to a broad spectrum of pathologies and are thus attractive therapeutic targets. Potential intervention strategies aiming at manipulation of these cells will require in-depth insights of their origins and the mechanisms that govern their homeostasis. The Ginhoux labs approach encompasses the integration of high dimensional platforms such as RNAseq, single cell transcriptome analysis using microfluidic RNA sequencing and deep immunophenotypic assessment (e.g. Cytometry by Time-Of-Flight mass spectrometry (CyTOF)).

Exciting topic or interested in chatting with Florent Ginhoux about his research? Then feel free to sign up via email (Karoline.laske@nct-dresden.de) for a short, in-person breakout session thereafter.

Clinicians will be rewarded with one continuing education point (SLÄK).

Date 12.10.2022

Time 12:00 CET /18:00 SGT

Speaker Prof. Florent Ginhoux

Host Dr. med. Julien Subburalayu

Zoom Link and more infos