The Institute of Pharmakologie und Toxikologie at the Herztage of the German Cardiac Society (DGK) in Hamburg

The presentations by Kevser Kocas on the project ‘C-peptide natriuretic peptide and vericiguat reduce proarrhythmic Ca²⁺ signals via phosphodiesterase 2 in heart failure’, and Dr Mario Schubert on the ’Downregulation of SRF-signaling drives polyploidy development of human induced pluripotent stem cell-derived cardiomyocytes in response to contractile activity’ were honored with the Hans-Jürgen-Bertschneider-Poster Prize of the Basic Science Meeting.

Kevser Kocas, Katharina Tergau, Paul Beck and Christian Hanisch were also supported by a travel stipend from the DGK.

In the poster session ‘Cardiovascular development and pharmacology’, Katharina Tergau presented her project ’Antiarrhythmic effects of the CNP analogue vosoritide via the phosphodiesterase 2-mediated cGMP/cAMP crosstalk in diabetic cardiomyopathy’.

Paul Beck presented recent results of his studies aiming to improve the maturation of engineered heart tissues under the title ‘The fine line between efficient maturation and metabolic stress in human engineered heart tissues’.

Christian Hanisch reported on the effects of a patient-specific mutation in the TRPC3 gene on human iPS cardiomyocytes in his presentation ‘Modelling the impact of the patient-specific TRPC3 mutation using induced pluripotent stem cell-derived cardiomyocytes’.

_{From left to right: Christian Hanisch, Katharina Tergau, Paul Beck, Kevser Kocas, Mario Schubert}