Nov 07, 2023
Herztage 2023 of the German Society of Cardiology in Bonn
f.l.t.r.: Erik Klapproth (upper panel); Rebecca Firneburg (lower panel); Johanna Schmidt; Prof. Kaomei Guan, Paul Beck, Mario Schubert (upper panel)); Sören Grell (lower panel).
The presentation of Johanna Schmidt/ Dr. Erik Klapproth on the project "Inhibition of the metalloprotease ADAM10 inhibits extracellular matrix remodeling after myocardial infarction" was awarded the Hans-Jürgen-Bertschneider-Posterpreis of the Basic Science Meeting in the poster session (Patho-) physiological heart remodelling. Johanna Schmidt, Paul Beck and Sören Grell also received a travel grant from the DGK.
Sören Grell presented the results of his medical doctoral thesis entitled "The CX3CL1 / CX3CXR1 axis regulates neutrophil heart tissue infiltration after myocardial infarction" in which he investigated a previously unknown population of neutrophils and their role after infarction.
Dr. Erik Klapproth presented under the title "Inhibition of the metalloprotease ADAM10 inhibits extracellular matrix remodeling after myocardial infarction" the latest research results on the influence of a specific neutrophil subpopulation on the composition of the scar after myocardial infarction, whose infiltration is regulated by the metalloprotease ADAM10.
Johanna Schmidt shows under the title "Inhibition of ADAM9 augments cardiac function after myocardial infarction" that not only the "A Disintegrin and Metalloprotease" ADAM10 is important after infarction, but also ADAM9 plays a crucial role for post-myocardial infarction cardiac function.
Rebecca Firneburg reports on the importance of phosphodiesterase 2 in the pathogenesis and arrhythmogenesis of diabetic cardiomyopathy entitled "PDE2 activation as a potential therapeutic strategy to treat diabetic cardiomyopathy-induced arrhythmogenesis".
Paul Beck shares under the title "Metabolic maturation and characterization of human engineered heart muscles" the results of his medical doctoral thesis on the maturation and functional characterization of heart muscle cells derived from induced pluripotent stem cells.
f.l.t.r.: Erik Klapproth, Johanna Schmidt, Sören Grell, Paul Beck, Rebecca Firneburg, Mario Schubert.