Publikationen

  • Pohl, C., Rau, C., Schuster, L., Gutbier, U., Beil, S., Lehmann, K., Börnick, H., Ostermann, K., Stolte, S. (2025) Genetically Engineered Yeast for Enhanced Biodegradation of Β‑lactam Antibiotics. Applied Biochemistry and Biotechnology. DOI: https://doi.org/10.1007/s12010-025-05291-4

  • Ostermann, K., Döring, J., Wolf, D. (2025) Silent Talks – artifizielle Kommunikation

    zwischen Bakterien und Hefen. BIOspektrum 31: 454-456, DOI: 10.1007/s12268-025-2511-z

  • Pohl, C., Schuster, L., Rau, C., Gutbier, U., Beil, S., Börnick, H., Ostermann, K., Stolte, S. (2025) LC-MS/MS quantification of bacterial and fungal signal peptides via direct injection: a case study of cross-kingdom communication. Analytical and Bioanalytical Chemistry 417:1677-1689, DOI: 10.1007/s00216-025-05767-6
  • Vološen, T., Gutbier, U., Korn, R., Korp, J., Göttsche, T., Schuster, L., Pohl, C.,Rau, C., Wolf, D., Ostermann, K. (2024) Controlled interkingdom cell-cell communication between Saccharomyces cerevisiae and Bacillus subtilis using quorum-sensing peptides. Frontiers in Microbiology 15, DOI: 10.3389/fmicb.2024.1477298
  • Kertsch, A.L., Brysch-Herzberg, M., Ostermann, K., Henle, T. (2024) Utilization of the Dicarbonyl Compounds 3-Deoxyglucosone and 3-Deoxymaltosone during Beer Fermentation by Saccharomyces Yeasts. Fermentation-Basel 10, DOI: 10.3390/fermentation10060281
  • Gutbier, U., Korp, J., Scheufler, L., Ostermann K. (2024) Genetic modules for α-factor pheromone controlled growth regulation of Saccharomyces cerevisiae. Eng. Life Sci. 24:e2300235. DOI: 10.1002/elsc.202300235
  • Simon, P., Pompe, W., Gruner, D., Sturm (née Rosseeva), E., Ostermann, K., Matys, S., Vogel, M., Rödel, G. (2022) Nested Formation of Calcium Carbonate Polymorphs in a Bacterial Surface Membrane with a graded Nano confinement - An Evolutionary Strategy to Ensure Bacterial Survival. ACS Biomaterials Science & Engineering 8:526-539, DOI: 10.1021/acsbiomaterials.1c01280
  • Rettke, D., Seufert, F., Döring, J., Ostermann, K., Wilms, D., Schmidt, S., Pompe, T. (2021) Biomimetic estrogen sensor based on soft colloidal probes. Biosensors and Bioelectronics (in press), DOI: 10.1016/j.bios.2021.113506
  • Hahne, K., Rödel, G., Ostermann, K. (2021) A fluorescence-based yeast sensor for monitoring acetic acid. Eng Life Sci 2021:1-11. https://doi.org/10.1002/elsc.202000006
  • Rettke, D., Döring, J., Martin, S., Venus, T., Estrela-Lopis, I., Schmidt, S., Ostermann, K., Pompe, T. (2020) Picomolar Glyphosate Sensitivity of an Optical Particle-based Sensor Utilizing Biomimetic Interaction Principles. Biosensors and Bioelectronics 165:112262, DOI: 10.1016/j.bios.2020.112262
  • Döring, J., Rettke, D., Rödel, G., Pompe, T. and Ostermann, K. (2019) Surface functionalization by hydrophobin-EPSPS fusion protein allows for the fast and simple detection of glyphosate. Biosensors 9:104 Link zum Paper
  • Guenther, M., Altenkirch, F., Ostermann, K., Rödel, G., Tobehn-Steinhäuser, I., Herbst, S., Görlandt, S. and Gerlach, G. (2019) Optical and impedimetric study of genetically modified cells for diclofenac sensing. J. of Sensors and Sensor Systems 8:215-222, DOI: 10.5194/jsss-8-215-2019
  • Hoffmann, A., Haas, C., Hennig, S., Ostermann, K., Bley, T., Löser, C. and Walther, T. (2019) Modeling population dynamics in a microbial consortium under control of a synthetic pheromone-mediated communication system. Eng Life Sci. 19:400-411, DOI: 10.1002/elsc.201800107
  • Schirmer, C., Posseckardt, J., Kick, A., Rebatschek, K., Fichtner, W., Ostermann, K., Schuller, A., Rödel, G., and Mertig, M. (2018) Encapsulating genetically modified Saccharomyces cerevisiae cells in a flowthrough device towards the detection of diclofenac in wastewater. Journal of Biotechnology 284:75–83
  • Hennig, S., Wenzel, M., Hass, C., Hoffmann, A., Weber, J., Rödel, G. and Ostermann, K. (2018) New approaches in bioprocess-control: consortium guidance by synthetic cell-cell communication based on fungal pheromones Eng Life Sci 18:387-400
  • Hennig, S., Hornauer, N., Rödel, G. and Ostermann, K. (2018) Pheromone-inducible expression vectors for fission yeast Schizosaccharomyces pombe. Plasmid 95: 1-6
  • Schuller, A., Rödel, G., Ostermann, K. (2017) Tuning the Sensitivity of the PDR5 Promoter-Based Detection of Diclofenac in Yeast. Biosensors. Sensors 17(7). pii: E1506.
  • Dietrich, C.P., Steude, A., Tropf, L., Schubert, M., Kronenberg, N.M., Ostermann, K., Höfling, S., and Gather, M.C. (2016) An exciton-polariton laser based on biologically produced fluorescent protein. Sci Adv. 2(8):e1600666
  • Gruner, L.J., Bahrig, L., Ostermann, K., Hickey, S.G., Eychmüller, A. and Rödel, G. (2016) Excitable Oil Droplets - FRET Across a Liquid-Liquid Phase Boundary. ChemistrySelect 1:4062-4067
  • Rödel, G. and Ostermann, K. (2016) Hefezellen als Sensoren und Aktoren in zellulären Netzwerken. Dresdner Transferbrief 2.16:6
  • Hennig, S., Rödel, G. and Ostermann, K. (2016) Hydrophobin-based surface engineering for sensitive and robust quantification of yeast pheromones Sensors 16(5), 602
  • Hennig, S., Rödel, G. and Ostermann, K. (2015) Artificial cell-cell communication as an emerging tool in synthetic biology applications. J Biol Eng 9:13
  • Blüher, A., Ostermann, K., Jäckel, P., Clemens, A., Katzschner, B., Rödel, G. and Mertig, M. (2015) Extraction and long-term storage of S-layer proteins and flagella from Lysinibacillus sphaericus NCTC 9602 as building blocks for nanotechnological applications. Eng Life Sci 15: 410-415
  • Ostermaier, F., Scharfenberg, L., Schneider, K., Hennig, S., Ostermann, K., Posseckardt, J., Rödel, G. and Mertig, M. (2015) Towards carbon nanotube-based biomembrane sensors for curvature sensitive proteins. Phys Stat Sol (a) 212:1389-1394
  • Hennig, S., Clemens, A., Rödel, G. and Ostermann, K. (2015) A yeast pheromone-based inter-species communication system. Applied Microbiology and Biotechnology 99:1299-308
  • Jahn, M., Mölle, A., Rödel, G. and Ostermann, K. (2013) Temporal and spatial properties of a yeast multi-cellular amplification system based on signal molecule diffusion. Sensors 13:14511-14522
  • Schuller, A., Auffermann, G., Zoschke, K., Schmidt, U., Ostermann, K. and Rödel, G. (2013) Over-expression of CTR1D300, a high-affinity copper transporter with deletion of the cytosolic C-terminus in Saccharomyces cerevisiae under excess copper leads to disruption of transition metal homeostasis and transcriptional remodelling of cellular processes. Yeast 30:201-18

  • Gruner, L.J., Ostermann, K. and Rödel, G. (2012) Layer thickness of hydrophobin films leads to oscillation in wettability. Langmuir 28:6942-6949 (DOI: 10.1021/la204252y)

  • Kottmeier, K., Günther, T., J., Weber, J., Kurtz, S., Ostermann, K., Rödel, G., and Bley, T. (2012) Constitutive expression of hydrophobin HFB1 from Trichoderma reesei in Pichia pastoris and its pre-purification by foam separation during cultivation. Eng Life Sci 12:162-170

  • Kothe, J., Schröter, A., Zarschler, K., Wersing, D., Mkandawire, M., Ostermann, K., Pompe, W., Rödel, G. and Gerlach, G. (2012) Optischer Biosensor auf Basis abhängiger Expression fluoreszierender Proteine. tm - Technisches Messen: 79:60-64
  • Knobloch, D., Ostermann, K. and Rödel, G. (2012) Production, secretion and cell surface display of recombinant Sporosarcina ureae S-layer fusion proteins in Bacillus megaterium. Appl Env Microbiol 78:560-567
  • Bobeth, M., Blecha, A., Blüher, A., Mertig, M.,  Korkmaz, N., Ostermann, K., Rödel, G. and Pompe, W. (2011) Formation of Tubes during Self-Assembly of Bacterial Surface Layers. Langmuir 27:15102-15111
  • Knobloch, D., Clemens, A., Ostermann, K. and Rödel, G. (2011) The xylA promoter of Bacillus megaterium mediates constitutive gene expression in Escherichia coli. Eng Life Sci 11:558-562
  • Kottmeier, K., Ostermann, K. and Rödel, G. (2011) Hydrophobin signal sequence mediates efficient secretion of recombinant proteins in Pichia pastoris. Appl Microbiol Biotechnol 91:133-141
  • Groß, A., Rödel, G. and Ostermann, K. (2011) Application of the yeast pheromone system for controlled cell-cell communication and signal amplification. Lett Appl Microbiol 52: 521-526
  • Korkmaz, N., Ostermann, K. and Rödel, G. (2011) Calcium dependent formation of tubular assemblies by recombinant S-layer proteins in vivo and in vitro. Nanotechnology 22: 095601
  • Thierfelder, S., Ostermann, K., Göbel, A. and Rödel, G. (2011) Vectors for glucose-dependent protein expression in Saccharomyces cerevisiae. Appl Biochem Biotechnol 163:954-964
  • Wolf, S., Rataj, F., Zierau, O., Ostermann, K., Diel, P., Parr, M.K., Vollmer, G. and Rödel, G. (2010) A novel combined approach to detect androgenic activities with yeast based assays in Schizosaccharomyces pombe and Saccharomyces cerevisiae. Toxicol Lett 199:410-415
  • Kottmeier, K., Ostermann, K., Bley, T. and Rödel, G. (2010) Herstellung von Hydrophobinen in Pichia pastoris. Chemie Ingenieur Technik 82:1545
  • Korkmaz, N., Ostermann, K., and Rödel, G. (2010) Expression and Assembly of Recombinant Surface Layer Proteins in Saccharomyces cerevisiae. Current Microbiology 62:266-373
  • Walther, T., Reinsch, H, Ostermann, K., Deutsch, A. and Bley, T. (2010) Applying dimorphic yeasts as model organisms to study mycelial growth: part 2. Use of mathematical simulations to identify different construction principles in yeast colonies. Bioprocess and Biosystems Engineering 34:21-31
  • Walther, T., Reinsch, H; Weber, P., Ostermann, K., Deutsch, A. and Bley, T. (2010) Applying dimorphic yeasts as model organisms to study mycelial growth: Part 1. Experimental investigation of the spatio-temporal.development of filamentous yeast colonies. Bioprocess and Biosystems Engineering 34:13-20
  • Ryzhkov, P., Ostermann, K., Blüher, A., Mertig, M. and Rödel G. (2007) Formation of self-assembly nanotemplates in vitro by native SslA protein and its truncation analysis. Phys Stat Sol (a) 204:1863-1869
  • Ryzhkov, P., Ostermann, K. and Rödel G. (2007) Isolation, gene structure, and comparative analysis of the S-layer gene sslA of Sporosarcina ureae ATCC 13881. Genetica 131:255-265
  • Hayat, S., Ostermann, K., Brusch, L., Pompe, W. and Rödel G. (2006) Towards in vivo computing: Quantitative analysis of an artificial gene regulatory network behaving as a RS flip-flop and simulating the system in silico. IEEE Bio-Inspired Models of Network, Information and Computing Systems. 1st: 1-7
  • Ostermann, K., Richter, M., Zscharnack, M., Rothe, R., Walther, T. and Rödel, G. (2006) Identification of the genes GPD1 and GPD2 of Pichia jadinii. DNA Sequence 17:452-457
  • Ostermann, K. and Rödel, G. (2006) Die Zellatmung: ein effizienter biologischer Prozess nicht ohne Risiken. Wiss Z TU Dresden 55:92-96
  • Khalimonchuk, O., Ott, M., Funes, S., Ostermann, K., Rödel, G., and Herrmann, J.M. (2006) Sequential processing of a mitochondrial tandem protein: Insights into the protein import in Schizosaccharomyces pombe. Euk Cell 5:997-1006
  • Walther, T., Reinsch, H., Ostermann, K., Deutsch, A. and Bley T (2005) Coordinated development of yeast colonies. B) Quantitative modeling of diffusion-limited growth. Engineering in Life Sciences 5, 125-133
  • Walther, T., Reinsch, H., Ostermann, K., Deutsch, A. and Bley, T. (2005) Coordinated development of yeast colonies. A) Experimental analysis of the adaptation to different nutrient concentrations. Engineering in Life Sciences 5, 115-124
  • Khalimonchuk, O., Ostermann, K. and Rödel, G. (2005) Evidence for association of yeast mitochondrial ribosomes with Cox11p, a protein required for CuB site formation of cytochrome c oxidase. Curr Genet 47:223-233
  • Walther, T., Reinsch, H., Große, A., Ostermann, K., Deutsch, A. and Bley, T. (2004) Mathematical modeling of regulatory mechanisms in yeast colony development. Journal of Theoretical Biology 229:327-338
  • Scholz, S., Domaschke, H., Kanamori, A., Ostermann, K., Rödel, G. and Gutzeit, H.O. (2004) Germ cell-less expression in medaka (Oryzias latipes). Mol Reprod Dev 67:15-18
  • Walther, T., Ostermann, K., Rödel, G., Agblevor, F. and Bley, T. (2002) Untersuchungen zur biotechnologischen Herstellung von Xylitol. Chemie Ingenieur Technik 74:664-665
  • Bartsch, O., Locher, K., Meinecke, P., Kress, W., Seemanova, E., Wagner, A., Ostermann, K. and Rödel, G. (2002) Molecular studies in 10 cases of Rubinstein-Taybi syndrome, including a mild variant showing a missense mutation in codon 1175 of CREBBP. J Med Genet 39:496-501
  • Bartsch, O., Meinecke, P., Locher, K., Kress, W., Pilz, M., Seemanova, E., Ostermann, K. and Rödel, G (2002) CREBBP mutations in 10 cases of Rubinstein-Taybi syndrome, including a mild variant showing a missense mutation. Eur J Hum Gen 10:234
  • Bartsch, O., Locher, K., Meinecke, P., Kress, W., Pilz, M., Ostermann, K. and Rödel, G. (2000) CBP mutation detection and genotype-phenotype correlation in patients with Rubinstein-Taybi syndrome (RTS) and a woman with presumably a mild RTS variant and normal intelligence. Am J Hum Gen 67:15
  • Krause-Buchholz, U., Tzschoppe, K., Paret, C., Ostermann, K. and Rödel, G. (2000) Identification of functionally important regions of the Saccharomyces cerevisiae mitochondrial translational activator Cbs1p. Yeast 16:353-363
  • Bartsch, O., Locher, K., Wagner, A., Ostermann, K. and Rödel, G. (2000) Detection of a C1108T transition within the CBP gene in a textbook patient with Rubinstein-Taybi syndrome. Eur J Hum Gen 8:152-153
  • Paret, C., Ostermann, K., Krause-Buchholz, U., Rentzsch, A. and Rödel, G. (1999) Human members of the SCO1 gene family: complementation analysis in yeast and intracellular localization. FEBS Lett 447:65-70
  • Rentzsch, A., Krummeck-Weiß, G., Hofer, A., Bartuschka, A., Ostermann, K. and Rödel, G. (1999) Mitochondrial copper metabolism in yeast: mutational analysis of Sco1p involved in the biogenesis of cytochrome c oxidase Curr Genet 35:103-108
  • Muris, D.F.R., Vreeken, K., Schmidt, H., Ostermann, K., Clever, B., Lohman, P.H.M. and Pastink, A. (1997) Homologous recombination in the fission yeast Schizosaccharomyces pombe: different requirements for the rhp51+, rhp54+ and rad22+ genes. Curr Genet 31:248-254
  • Muris, D.F.R., Bezzubova, 0., Buerstedde, J.-M., Vreeken, K., Balajee, A.S., Osgood, C.J., Troelstra, C., Hoeijmakers, J.C.J., Ostermann, K., Schmidt, H., Natarajam, A.T., Ecken, J.C.J., Lohmann, P.H.M. and Pastink, A. (1994) Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination. Mut. Res. 315:295-305
  • Michael, H., Schmidt, H., Fleck, 0., Gutz, H., Liedtke, C., Lorentz, A. and Ostermann, K. (1994) The mating-Type region of Schizosaccharomyces pombe contains an essential gene encoding a protein homologous to human modulators of HIV transactivation. Gene 145:205-2 10
  • Lorentz, A., Ostermann, K., Fleck, 0. and Schmidt, H. (1994)  Switching gene swi6, involved in repression of silent mating-type loci in fission yeast, encodes a homologue of chromatin-associated proteins from Drosophila and mammals. Gene 143:139-143
  • Bezzubova, O.Y., Schmidt, H., Ostermann, K., Heyer, W.-D. and Buerstedde, J.M. (1993) Identification of a chicken RAD52 Homologue suggests conservation of the RAD52 recombination pathway throughout the evolution of higher eukaryotes. Nucl. Acids Res. 21:5945-5949
  • Ostermann, K., Lorentz, A. and Schmidt, H. (1993) The fission yeast rad22 gene, having a function in mating-type switching and repair of DNA damages, encodes a protein homolog to Rad52 of Saccharomyces cerevisiae. Nucl. Acids Res. 21:5940-5944
  • Schlake, C., Ostermann, K., Schmidt, H. and Gutz, H. (1993) Analysis of DNA repair pathways of Schizosacharomyces ponbe by means of swi-rad double mutants. Mut. Res. 294:59-67

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Gerd Bombach
Letzte Änderung: 30.06.2025