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We are an international group of researchers that study the metabolism of the central nervous system focusing on carbohydrate uptake and distribution. We are fascinated by the metabolic interactions between different brain cells, supported by the selective transport of nutrients by the blood-brain-barrier (BBB) and their fate. In the past we have generated evidence supporting the astrocyte-neuron lactate shuttle (ANLS) hypothesis, using the Drosophila model and its powerful genetic tools. Amongst other applications, our research provides insights in neurodegenerative diseases caused by disturbed metabolism.

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