10.01.2025
New Publication - PnP System for PoTeM Production and Functionalization in Microb. Cell Fact.
Check out our new publication about A plug-and-play system for polycyclic tetramate macrolactam production and funtionalization in Microbial Cell Factories! This work contains the reconstruction of the ikarugamycin biosynthesis and generation of five selectively modified derivatives of ikarugamycin. Our platform will generally facilitate the investigation of new PoTeM biosynthetic cyclization and tailoring reactions in the future.
Congratulations to Anna and Basti on this great scientific achievement with lots of cloning, screening, extraction, and compound isolation works!