Aug 24, 2022
Recent publication
First Synthesis, Confirmation of Stereochemistry, and Cytotoxic Activity of Oxyfungiformin
The relative configuration of the marine sesquiterpenoid oxyfungiformin, isolated from the soft coral Capnella fungiformis , was confirmed by synthesis using the natural product guaiol as chiral precursor. The absolute configuration of oxyfungiformin could be assigned by combination of X-ray diffraction and comparison of the values for the specific optical rotation. Oxyfungiformin and a diastereoisomer showed cytotoxic activity in cells originating from cancers of the lung, breast, and cervix.
https://doi/abs/10.1002/ejoc.202200809