Cooperation
We conduct both standardised (e.g. OECD) as well as customised, task-specific test to investigate the environmental behaviour and impacts of chemicals. Our main areas of expertise are:
Toxicity
- Luminescence inhibition test with marine bacteria (Aliivibrio fischeri) based on DIN 11348 standard
- Green algae acute test (Rhapidocelis subcapitata) according to OECD 201 procedure
- Acute Daphnia magna (water flea) immobilisation test according to OECD 202 procedure
- Chronic Daphnia magna (water flea) reproduction inhibition test according to OECD 2011 procedure
- Lemna minor (duck weed) sub-chronic growth inhibition test according to OECD 221 guideline
- Activated sludge respiration inhibition test according to OECD 209 test procedure
- Passive dosing to maintain stable exposure during tests (in most of the above mentioned test systems)
Biodegradability
- primary biodegradation tests supported by targeted analysis of the test compound and biotransformation products
- ready biodegradability test using the manometric respirometry method according to OECD 301F
- biodegradation simulation test using an automated model wastewater treatment plant (nitrification-denitrification setup with excess sludge recirculation)
Partitioning and mobility in soils, sediments and sludge:
- Sorption/desorption in soils, sediment and sludge using equilibrium batch tests (OECD 106)
- Mobility and leaching in soil columns (OECD 312)
- Estimation of the soil or sludge organic matter partition coefficient (log Koc) using HPLC-method according to OECD 121 procedure
Physiological partitioning and bioaccumulation:
- Lipid binding
- Protein binding
Environmentally relevant physicochemical properties:
- Solubility using shake flask or column elution method (OECD 105)
- Octanol-water partition coefficient using slow stirring method (OECD 123)
- Susceptibility to hydrolysis (OECD 111)
Analytics:
- Gas chromatography – mass spectrometry (GC-MS)
- Liquid chromatography - mass spectrometry (LC-MS)
- Liquid chromatography with DAD detection
- Ion chromatography (inorganic and organic ions)
- Total/dissolved carbon and nitrogen
- Cell count and size distribution