Biomolecular Interactions

DNA-encoded chemical library: by tagging millions to billions of different chemical structures with DNA strands as barcodes, we can mimic the selection process of biology to discover new bioactive compounds.

Small molecule array: We develop fully automated parallel synthesis technology, to allow high throughput synthesis meet the requirements of high throughput screening.

Self-assembled biomatrices: We design and synthesize self-assembled biomaterials, for understanding the dynamics of extracellular matrices, to recapitulate and model various biological niches, and to develop novel therapeutical tools.

Peptidyl-prolyl cis/trans isomerase: We study the isomerization of peptidyl-prolyl bond, one of the smallest chemical changes in the biological world.