CMCB Life Sciences Seminar: Prof. Peter Sudmant, University of California Berkeley, USA

Host: Anna Poetsch (BIOTEC)

Title: “Evolution of structural variation and mutation across vertebrates”

Abstract: Structural variants (SVs) contribute substantially to genetic variation and play vital roles in adaptation and disease. However, SVs are poorly captured by short read sequencing and thus are understudied, particularly in non-model organisms. Here, taking advantage of recently generated haplotype-resolved genome assemblies from >600 vertebrate species, we present the most comprehensive survey of the diversity of SVs and single nucleotide variants (SNVs) across the vertebrate tree of life to date.