Extraordinary Seminar - Jun.-Prof. Kai Markus Schneider, RWTH Aachen University

Host: Prof. Jochen Hampe

Title: “Stessing the Gut-Brain Axis”

Abstract: The majority of human diseases involve complex interactions of different cellular and organ systems. Traditional organ-centric pathophysiological models fail to capture these interactions.

This talk outlines circuits of organ crosstalk in the gastrointestinal tract with a focus on the gut-liver-brain axis. It elucidates the intricate molecular circuits involved in gut-liver crosstalk, expounding on how they underpin vital physiological processes and how they are changed in disease. Recently, we identified the impact of glucocorticoids on enteric glia and neurons and discovered the underlying mechanism that relays psychological stress to the exacerbation of gut inflammation (1).

The talk will highlight new data on the emerging field of neuro-immune interactions and discuss potential implications for colorectal cancer and tissue regeneration.

Everybody is very welcome.