Adaptive individualized implants for large-area cranioplastic restoration
| Term | 01.01.2025 - 30.06.2027 |
| Overall project | Adaptive individualized implants for large-area cranioplastic treatment |
| Subproject | Algorithms for 3D data processing |
| Acronym | AdInKranio |
| Project funding | ERDF R&D joint project funding 2021-2027 (SAB) |
| Funding code | 100741563 |
| Project management | |
| Processor | Dr.-Ing. Philipp Sembdner |
| Partner |
INNOTERE GmbH, Radebeul |
The AdInKranio research project aims to develop innovative, individualized implants for the treatment of large cranial defects. Conventional methods for reconstructing these defects regularly reach their limits in that they cannot meet the individual needs of patients in terms of shape, size and biological compatibility.
This project aims to develop new, adaptive implants that can be customized to the specific requirements of each individual patient. The focus is on establishing a continuous and efficient process chain that makes it possible to manufacture such implants quickly and precisely. A particularly innovative technology variant of additive manufacturing (3D printing) is used, which simultaneously offers a high degree of flexibility and precision in production.
A unique feature of the implants to be developed is their multi-part structure, which allows them to be flexibly adapted to different conditions. This modularity is crucial, particularly in the treatment of children, whose skull shape and size are subject to change as they grow. The implants should be able to adapt to changing conditions without the need for additional surgical interventions. In addition, the implants should combine different material properties, a dense layer to protect the brain and a porous layer that promotes bone growth and thus improves the integration of the implant into the skull bone.
In order to find the best possible solution, the project is researching methods for dividing the implants into different segments. This segmentation facilitates the production and surgical handling of the implants. Approaches are being investigated to securely connect the parts together using materials that can biodegrade over time.
Another focus of the project is the development of a simulation model with which the mechanical load and durability of the implants can be tested virtually before they are manufactured. These simulations should help to design the implants in such a way that they can withstand the demands of everyday life and at the same time support the healing process.
The project partners are working closely with medical specialists to ensure that the implants are both technically mature and suitable for clinical use. The overall system is validated by manufacturing demonstrators that are tested in real-life scenarios. In addition, economic and, in particular, regulatory aspects must be taken into account.
The project is expected to significantly improve the care of patients with cranial defects by developing individualized, flexible and highly biocompatible implants that considerably expand the current state of the art in medical technology. The results of this project should make an important contribution to improving the quality of life of affected patients in the future and sustainably advance surgical practice.
