Research projects

Current research projects

• POET - Development of an efficient biotechnological production process for the sustainable chromophore xylindein with multifunctional use in refinement technology
• smartFormulation - Development of an automated, function-integrated system for the production and quality assessment of insoluble mixed compounds in pharmaceuticals, biotechnology and cosmetics
• SmartAQAlab - Development of a semi-automated assistance system for the multi-parametric analysis of drinking and process water
• dOxy2SensE - Dissolved-O2 Sens-o-Spheres Expansion

• CellPAT - Novel process analytics technology for cell stack cultivation environments

• hyperBATH - Novel multi-site reaction system with integrated sensor technology and embedded cloud connection for aggregated data analysis

• iHexagon - Development, construction and testing of an intelligent, multivariant, autonomous, mobile laboratory furniture system with LIMS connectivity as the basis for function-integrative elements in the laboratory of the future

• LiquiPlate - Development, construction and testing of an automated system for concentrating and plating liquid samples in culture dishes with automated incubation and inspection

• SteriBot - Development of an automation system for the sterility testing of radiopharmaceuticals

• Digitalalgae: Microalgal population dynamics related to changes of environmental conditions
• Formation of silver nanoparticles from galvanic wastewater with the help of filamentous fungi

• AquaTechLausitz - Innovation alliance of post-fossil aquatic resources for a sustainable industrial structural change in the Lusatian mining area

• SchuPlaHolz_Biobased protective agent from plant cell culture for wood-based materials
• iPhoto - Development and testing of an automatic photo station for recording, documenting and measuring laboratory samples and connection to a LIMS
• Smart Translation - Optimization of diagnostics in personalized oncology through the development of an efficient analysis system for the exploration, validation and translation of new molecular biological biomarkers and SmartLab integration
• Development of a synthetic metabolic pathway for the carbon-conserving production of acetyl-CoA from ethylene glycol (funded by the DFG)
• Enzyme cascades for cell-free ATP regeneration for the synthesis of valuable substances (funded by ZIM, cooperation with c-LEcta)
• CoBioMetal - Combined biotechnological and electrochemical wastewater valorization for metal recovery. Sub-project: Systems biology study of fungal strains during metal recovery from process wastewater (funded by the SAB, cooperation with TU Bergakademie Freiberg)
• KoSyn - Controlled synergy: Peptide-controlled cell-cell communication of yeasts and bacteria in (bio)technological processes (funded by the ESF, cooperation between the Chairs of General Genetics, General Microbiology, Hydrochemistry, all TU Dresden)
• EtAc- Process development for the production of ethyl acetate from whey residues - Microbial ester synthesis and innovative process-integrated product separation

• Simulation of radiation conditions in horizontal tubular photobioreactors

• Application of additive manufacturing technologies for the realization of medically relevant cocultures from mammalian cells and microalgae

• MOProAlge: Rapid monitoring system to optimize process control for the production of active ingredients using microalgae

• 3Dbot - Development of a high-throughput, bench-top robotic system for the fully automated handling of biological samples using a photogrammetric 3D imaging method and real-time image analysis

• iChemCabinet - Development and testing of a universal, interactive, intelligent laboratory cabinet for handling and dispensing chemicals from containers with screw caps

Completed research projects

• Sens-o-Spheres III - Characterization of novel bioreactor systems by spatially and time-resolved recording of process measurement signals with mobile, miniaturized sensors
• SmartAquaCultureSystems - Novel energy-optimized recirculation systems with mobile, wireless sensor equipment
• ActiveEndoTest - Development of a novel active system for removing endotoxins from human body fluids with the aim of a rapid test
• SchuPlaHolz - Feasibility study_Biobased protective agent from plant cell culture for wood-based materials
• Algae4Cycle - Modular on-site plant for the algae-based treatment of process wastewater

• Model-based continuous cultivation of the cyanobacterium Arthrospira platensis on a technical scale

• NanoFunDus - Development of a new antifouling coating to prevent micro- and macro-fouling in heat exchangers using the example of seawater desalination plants

• Toxicologically safe new crosslinker systems for the collagen industry based on biotechnological processes

• ß clean: Avoiding the spread of anthropogenic trace substances in aquatic habitats through the technical use of aptamers

• Extraction of resource-saving, high-quality and health-promoting valuable substances from microalgae for use in the cosmetics and pharmaceutical industries

• CrossCat symbiosis of biological & chemical catalysts for the sustainable conversion of hemicelluloses

• Yeast pheromones for controlling biotechnological processes (HeSPro)

• Development of technologies and processes for the cultivation of dye-producing fungi and for the extraction of natural dyes.

• Green Bioprinting - Novel agglomeration environment for plant cells

• BioSpeckle - Development of a laser-optical sensor system for non-invasive biomass determination in biotechnological processes

• Sens-o-Spheres II | Location-independent recording of process measurement signals in novel bioreactor systems

• SmartVesselCoatTest - Development of a novel, self-cleaning, biocide-free coating system for pleasure craft including an inline test method for the validation of antifouling properties.

• Design, development, testing and validation of a novel filter for integration into a home care test for the detection of Chlamydia trachomatis

• CQS-ACM - SPR system for the automated and process-integrated continuous determination of active concentrations

• MIPHO multispectral bioreactor for phototrophic organisms
• eLABPS - Stereoscopy in biotechnology and the life sciences: Investigations into image generation in biological samples and possibilities for automatic image analysis using the example of Legionella pneumophila.
• Development and validation of new types of surface structuring with the aim of providing anti-(bio)-fouling coatings

• Development and testing of a laboratory bench-top device for generating variable magnetic fields for mixing cells with suspended magnetic particles in a targeted manner in sample vessels

• New production system for plant secondary metabolites based on cell-free biocatalysis in a cascaded, compartmentalized hairy root reactor

• Symbiosis of catalysis and biotechnology for the sustainable utilization of hemicelluloses in biorefineries
• NutriJet - Development and testing of a laboratory bench-top device for the fully automated production of liquid culture media
• CultiLux - Development and establishment of an innovative device for the illumination of phototrophic and photomixotrophic organisms in orbitally shaken culture vessels
• ZMWBioKat: Metallic foams in biosensors
• Development of fungicidal and hydrophobic protective agents from plants and development and production of a novel natural insulating material

• Sens-o-Spheres | Location-independent recording of process measurement signals in novel bioreactor systems

• Development of an industrial biofilm formation monitoring system with a robust, multi-parametric sensor system, creation of requirement profiles and its experimental testing

• BioGlizz: Biological alternative to artificial snow for worldwide use

• Scientific development of instructions for the cultivation and packaging of yeast for the A-YES assay on a production scale

• Development of an innovative OLED-based screening system for phototrophic microorganisms (OLEmibi)

• Solid state fermentation of white rot fungi - investigation and modeling of the growth process

• PetriJet - Development of a device for automatic image acquisition and quantitative image analysis of plant in vitro hairy root networks in culture dishes

• White biotechnology for hydrogen synthesis - development of process principles for the production of biogenic hydrogen in innovative photobioreactors by an interdisciplinary junior research group

• Innovative production of secondary ingredients from blue-green algae for natural cosmetic and pharmaceutical products

• Development of a universal lab-on-a-chip platform for the automated and validated characterization of analyte-ligand and cell-analyte interactions

• Adhesion tendency, wear properties and cleaning effort when using ta-C coatings with and without doping in food processing

• Extraction of pharmacologically relevant triterpenes from plant cell cultures using the example of oleanolic and ursolic acid

• Aptamer-based multi-sensor system for pathogen detection

• White biotechnology with plant cells: Transfer of innovative processes for the application of plant cells in the food, wood-based materials, pharmaceutical and cosmetics industries by an interdisciplinary junior research group

• Production of ethyl acetate by Kluyveromyces marxianus

• Development of a process for the production of enzyme mixtures to accelerate solid matter fermentation processes

• Intelligent control of NawaRo plants to increase the biogas yield

• Optimization of substrate pretreatment through the use of enzymes in the hydrolysis stage

• Bio-SAT - Biological whole-cell sensor-actuator systems for bioprocess engineering and environmental technology: Production of recombinant hydrophobins in the yeast Pichia pastoris

• BIOMINT - Biomimetic mineralization for engineering

• Process engineering for white biotechnology: transfer of biotechnological syntheses to industry

• Alternative surface systems and biomonitoring

• Isolation of Staphylococcus aureus from food using biomagnetic separation and new detection methods such as surface plasmon resonance-based biosensors

• Bioprocess engineering research for scale transfer in white biotechnology

• Biosensor system for the determination of triglycerides in different sample materials

• Development of robust reactor technology for decolorization and detoxification of textile wastewater with enzymes

• New enzymes - innovatively immobilized - for use in decolourization and bleaching processes in the textile industry

• Identification and quantification of phosphate-accumulating organisms (PAO) in activated sludge from various municipal wastewater treatment plants

• Microbial diagnostics of food and pharmaceuticals - IKON 1&3 growth core

• Rapid biomonitoring based on biomagnetic separation and nanotechnology - LÖBISENA

• Flow-cytometric online monitoring for process control

• Development of biosensors for solid state fermentation - BIOMUSE

• Characterization of the activation state of spores

• Rapid biomonitoring of contaminants in material systems from the food industry

• Production-integrated biomonitoring - use of molecular biological and genetic methods

• Development of methods for flow-cytometric analysis of transient-state cultivations

• Flow-cytometric online biomonitoring of yeasts in biotechnical processes

• Innovative process water recycling of dyeing wastewater - "OXITEX"

• Packaging with antimicrobial properties

• Biological digestion of genetically modified bacteria with bdellovibrions to extract active ingredients

• Intelligent bio- and microsystems technology - a new generation of devices for wastewater treatment

• Microorganisms under stringent conditions - analysis and modeling of yeast colony growth

• Process development for the bioproduct synthesis of plant cells

• Cleaning and surface modification