Prof. Dr. med. Richard H.W. Funk
Persönliche Daten
1973-1979 | Studium der Medizin, Universität Erlangen-Nürnberg |
1976-1979 | Promotion, Universität Erlangen-Nürnberg |
1980 | Wissenschaftlicher Mitarbeiter, Institut für Anatomie, Universität Erlangen-Nürnberg |
1981–1982 | Millitärdienst als Praktischer Arzt in Regensburg |
1982–1986 | Assistant professor, University Erlangen-Nürnberg |
1986 | Habilitation in Anatomie, Dr. med. habil., Universität Erlangen Nürnberg |
1988 | Professur für Anatomie, Universität Erlangen-Nürnberg |
1994 - present | Leiter des Instituts für Anatomie an der Medizinischen Fakultät Carl-Gustav-Carus, Technische Universität Dresden |
andere akademische Positionen
1999-2003 | Prodekan der Medizinischen Fakultät Carl-Gustav-Carus, Technische Universität Dresden |
2000-2006 | Vorstandsmitglied der Anatomischen Gesellschaft (Anatomical Society, international) |
2004-present | Fachkollegiat der DFG "Grundlagen der Biologie und Medizin, Anatomie" |
2009 | Kurator am Fraunhofer Institut für Elektrostrahl- und Plasmatechnik (FEP) |
April 2010 | Mitglied des Senats der Technischen Universität Dresden |
Lehre
Makroskopische Anatomie, Allgemeine Anatomie, Embryologie, Neuroanatomie, Histologie
Forschungsprojekte
frühere: | |
aktuelle: |
Nervenzellen, Retina und Auge |
Ausgewählte Publikationen
- Ozkucur N, Monsees TK, Perike S, Do HQ, Funk RH
Local calcium elevation and cell elongation initiate guided motility in electrically stimulated osteoblast-like cells.
PLoS One. 2009 Jul 3;4(7):e6131. PubMed PMID: 19584927; PubMed Central PMCID: PMC2702840 - Funk RH, Monsees T, Ozkucur N
Electromagnetic effects - From cell biology to medicine.
Prog Histochem Cytochem. 2009;43(4):177-264. Epub 2008 Sep 18. Review. PubMed PMID: 19167986 - Knels L, Valtink M, Roehlecke C, Lupp A, de la Vega J, Mehner M, Funk RH
Blue light stress in retinal neuronal (R28) cells is dependent on wavelength range and irradiance.
Eur J Neurosci. 2011 Aug;34(4):548-58. doi: 10.1111/j.1460-9568.2011.07790.x. PubMed PMID: 21781192 - Ozkucur N, Perike S, Sharma P, Funk RH
Persistent directional cell migration requires ion transport proteins as direction sensors and membrane potential
differences in order to maintain directedness.
BMC Cell Biol. 2011; Jan 22;12:4. PubMed PMID: 21255452; PubMed Central PMCID: PMC3042415. - Aryasomayajula A, Derix J, Perike S, Gerlach G, Funk RH
DC microelectrode array for investigating the intracellular ion changes.
Biosens Bioelectron. 2010; Dec 15;26(4):1268-72. Epub 2010 Jul 6. PubMed PMID: 20656468. - Pan-Montojo F, Anichtchik O, Dening Y, Knels L, Pursche S, Jung R, Jackson S, Gille G, Spillantini MG, Reichmann H, Funk RH
Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice.
PLoS One. 2010 Jan 19;5(1):e8762; PubMed PMID: 20098733 - Knels L, Worm M, Wendel M, Roehlecke C, Kniep E, Funk RH
Effects of advanced glycation end products-inductor glyoxal and hydrogen peroxide as oxidative stress factors on rat
retinal organ cultures and neuroprotection by UK-14,304
J Neurochem. 2008 Aug;106(4):1876-87. Epub 2008 Jul 4; PubMed PMID: 18624919 - Roehlecke C, Schaller A, Knels L, Funk RH
The influence of sublethal blue light exposure on human RPE cells.
Mol Vis. 2009 Sep 21;15:1929-38; PubMed PMID: 19784391; PubMed Central PMCID: PMC2751800 - Kniep EM, Roehlecke C, Ozkucur N, Steinberg A, Reber F, Knels L, Funk RH
Inhibition of apoptosis and reduction of intracellular pH decrease in retinal neural cell cultures by a blocker of carbonic anhydrase.
Invest Ophthalmol Vis Sci. 2006 Mar;47(3):1185-92; PubMed PMID: 16505057 - Krafft C, Knetschke T, Funk RH, Salzer R
Studies on stress-induced changes at the subcellular level by Raman microspectroscopic mapping.
Anal Chem. 2006 Jul 1;78(13):4424-9; PubMed PMID: 16808450 - Roehlecke C, Schumann U, Ader M, Brunssen C, Bramke S, Morawietz H, Funk RH
Stress reaction in outer segments of photoreceptors after blue light irradiation.
PLoS One. 2013 Sep 11;8(9):e71570. doi: 10.1371/journal.pone.0071570. eCollection 2013 - Pan-Montojo F, Schwarz M, Winkler C, Arnhold M, O'Sullivan GA, Pal A, Said J, Marsico G, Verbavatz JM, Rodrigo-Angulo M, Gille G, Funk RH, Reichmann H
Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice.
Sci Rep. 2012;2:898. doi: 10.1038/srep00898. Epub 2012 Nov 30 - Funk RH
Functional Differences in the Microcirculatory Units of the Eye.
Klin Monbl Augenheilkd. 2015 Jan 14. [Epub ahead of print] German. PubMed PMID: 25587887 - Roehlecke C, Schumann U, Ader M, Brunssen C, Bramke S, Morawietz H, Funk RH
Stress reaction in outer segments of photoreceptors after blue light irradiation.
PLoS One. 2013 Sep 11;8(9):e71570. doi: 10.1371/journal.pone.0071570. eCollection 2013. PubMed PMID: 24039718; PubMed Central PMCID: PMC3770596 - Wittig D, Jászai J, Corbeil D, Funk RH
Immunohistochemical localization and characterization of putative mesenchymal stem cell markers in the retinal capillary network of rodents.
Cells Tissues Organs. 2013;197(5):344-59. doi: 10.1159/000346661. Epub 2013 Apr 3. PubMed PMID: 23571553 - Pan-Montojo F, Funk RH
Implications of Parkinson's disease pathophysiology for the development of cell replacement strategies and drug discovery in neurodegenerative diseases.
CNS Neurol Disord Drug Targets. 2012 Nov 1;11(7):907-20. Review. PubMed PMID: 23131153 - Ozkucur N, Song B, Bola S, Zhang L, Reid B, Fu G, Funk RH, Zhao M
NHE3 phosphorylation via PKCη marks the polarity and orientation of directionally migrating cells.
Cell Mol Life Sci. 2014 Dec;71(23):4653-63. doi: 10.1007/s00018-014-1632-1. Epub 2014 May 1. PubMed PMID: 24788043 - Perike S, Özkucur N, Sharma P, Staroske W, Bläsche R, Barth K, Funk RH
Phospho-NHE3 forms membrane patches and interacts with beta-actin to sense and maintain constant direction during cell migration.
Exp Cell Res. 2014 May 15;324(1):13-29. doi: 10.1016/j.yexcr.2014.03.005. Epub 2014 Mar 19. Erratum in: Exp Cell Res. 204 Aug 1;326(1):185. PubMed PMID: 24657527 - Wittig D, Wang X, Walter C, Gerdes HH, Funk RH, Roehlecke C
Multi-level communication of human retinal pigment epithelial cells via tunneling nanotubes
PLoS One. 2012;7(3):e33195. doi: 10.1371/journal.pone.0033195. Epub 2012 Mar 22. PubMed PMID: 22457742; PubMed Central PMCID: PMC3310865