Publications

RECENT PUBLICATIONS

• Skrupskelyte, G., Rojo Arias, J. E., Ajith, H., Dang, Y., Rossetti, D., Han, S., Tang, M. K. S., Bejar, M. T., Colom, B., Fowler, J. C., Murai, K., Knight, W., Aust, D., Schmidt, M. H. H., Jászai, J., Zeki, S., Noorani, A., Jones, P. H., Rulands, S., Simons, B. D., … Alcolea, M. P. (2026) Precancerous niche remodelling dictates nascent tumour persistence. Nature,  https://doi.org/10.1038/s41586-026-10157-8. PMID: 41781610. (Impact Factor 48.5)
• Ehret F, Doludda B, Liu H, Nexhipi S, Huang H, Rost F, Overall RW, Barde W, Rünker AE, Sieweke M, Dahl A, Schmidt MHH*, Kempermann G* (2025) Lifestyle shapes preclinical social and microglial deficits in an Alzheimer's disease mouse model. Molecular Psychiatry. doi: 10.1038/s41380-025-03368-4. PMID: 41388145. (Impact Factor 10.1)
• Mahajan S, Abe P, Ehret F, Fabian C, Gentzel M, Gupta R, Dahl A, Schumann U, Schmidt MHH* (2025) THE EGFL7–INTEGRIN β2 AXIS: A novel regulator of immune evasion in glioblastoma. Neuro-Oncology 27 (Suppl_3), iii83–iii84. doi: 10.1093/neuonc/noaf193.274. (Impact Factor 13.4)
• Mahajan S, Schumann U, Schmidt MHH* (2025) EGFL7, an angiogenic factor, induces immunosuppression in malignant glioma. Journal for ImmunoTherapy of Cancer 13, P-03.06. doi: 10.1136/jitc-2025-ITOC11.37. (Impact Factor 10.6)
• Fabian C, Mahajan S, Schmidt MHH* (2025) EGFL7: An emerging biomarker with great therapeutic potential. Pharmacology & Therapeutics 266, 108764. doi: 10.1016/j.pharmthera.2024.108764. PMID: 39631508. (Impact Factor 13.5)
• Mahajan S, Abe P, Ehret F, Fabian C, Heinig N, Barth K, Gentzel M, Gupta R, Aprea J, Warnke P, Wasser B, Grabbe S, Schmitz M, Dahl A, Zipp F*, Schumann U*, Schmidt MHH* (2025) EGFL7 promotes immune evasion in glioma through its interaction with integrin β2. bioRxiv preprint. doi: 10.1101/2025.07.28.667281.
• Mahajan S, Schmidt MHH*, Schumann U* (2025) EGFL7, an angiogenic protein, acts as an immunosuppressive factor in glioma development. Annals of Anatomy 260, 152404. doi: 10.1016/j.aanat.2025.152404.

Publications Prof. Schmidt

TOP 10 PUBLICATIONS

• Nevenka Dudvarski Stanković, Frank Bicker, Stefanie Keller, David T. W. Jones, Patrick N. Harter, Arne Kienzle, Clarissa Gillmann, Philipp Arnold, Anna Golebiewska, Olivier Keunen, Alf Giese, Andreas von Deimling, Tobias Bäuerle, Simone P. Niclou, Michel Mittelbronn, Weilan Ye, Stefan Pfister & Mirko HH Schmidt (2018) EGFL7 enhances surface expression of integrin α₅ß₁ to promote angiogenesis in malignant brain tumors. EMBO Mol Med pii: e8420. (Impact Factor 10.6)
• Catherine Larochelle, Timo Uphaus, Bieke Broux, Elizabeth Gowing, Magdalena Paterka, Laure Michel, Nevenka Dudvarski Stankovic, Frank Bicker, Alexandre Prat*, Mirko HH Schmidt* & Frauke Zipp* (2018) EGFL7 reduces CNS inflammation in mouse. Nature Comm 9 (1), 819. ^*Corresponding authors (Impact Factor 11.9)
• Frank Bicker, Verica Vasić, Guilherme Horta, Felipe Ortega, Hendrik Nolte, Atria Kavyanifar, Stefanie Keller, Nevenka Dudvarski Stanković, Patrick N. Harter, Rui Benedito, Beat Lutz, Tobias Bäuerle, Jens Hartwig, Jan Baumgart, Marcus Krüger, Konstantin Radyushkin, Lavinia Alberi, Benedikt Berninger & Mirko HH Schmidt (2017) Neurovascular EGFL7 regulates subventricular neural stem cells, neurogenesis and olfactory perception. Nature Comm 8, 15922 (Impact Factor 12.4)
• Nevenka Dudvarski Stanković, Marcin Teodorczyk, Robert Ploen, Frauke Zipp, Mirko HH Schmidt (2016) Microglia–blood vessel interactions: a double-edged sword in brain pathologies. Acta Neuropathol 131 (3), 347-363 (Impact Factor 12.2)
• Valérie Jolivel, Frank Bicker, Fabien Binamé, Robert Ploen, Stefanie Keller, René Gollan, Betty Jurek, Jérôme Birkenstock, Laura Poisa-Bei­ro, Julia Bruttger, Verena Opitz, Serge C. Thal, Ari Waisman, Tobias Bäuerle, Michael K. Schäfer, Frauke Zipp, Mirko HH Schmidt (2015) Perivascular microglia promote blood vessel disintegration in the ischemic penumbra. Acta Neuropathol 129 (2), 279-295. (Impact Factor 10.8)
• Iva Nikolić, Nevenka Dudvarski Stanković, Frank Bicker, Jeannette Meister, Helene Braun, Khader Awwad, Jan Baumgart, Kirsten Simon, Serge C. Thal, Chinmoy Patra, Patrick N. Harter, Karl H. Plate, Felix B. Engel, Stefanie Dimmeler, Johannes A. Eble, Michel Mittelbronn, Michael K. Schäfer, Benno Jungblut, Emmanouil Chavakis, Ingrid Fleming & Mirko HH Schmidt (2013) EGFL7 ligates endothelial α_Vβ₃ integrin to enhance vessel formation. Blood 121 (15), 3041-3050. (Impact Factor 9.8)
• Virginia Guarani, Gianluca Deflorian, Claudio A. Franco, Marcus Krüger, Li-Kun Phng, Katie Bentley, Louise Toussaint, Franck Dequiedt, Raul Mostoslavsky, Mirko HH Schmidt, Barbara Zimmermann, Ralf P. Brandes, Marina Mione, Christoph H. Westphal, Thomas Braun, Andreas M. Zeiher, Holger Gerhardt, Stefanie Dimmeler & Michael Potente (2011) Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase. Nature 473 (7346), 234-238. (Impact Factor 36.3)
• Mirko HH Schmidt^*, Frank Bicker, Iva Nikolić, Jeannette Meister, Tanja Babuke, Srdjan Picuric, Werner Müller-Esterl, Karl H. Plate & Ivan Dikić^* (2009) Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal. Nat Cell Biol 11 (7), 873-880. ^*Corresponding authors. (Impact Factor 19.5)
• Mirko HH Schmidt & Ivan Dikić (2005) The Cbl interactome and its functions. Nat Rev Mol Cell Biol 6 (12), 907-919. (Impact Factor 29.9)
• Mirko HH Schmidt, Frank B. Furnari, Webster K. Cavenee & Oliver Bogler (2003) Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization. PNAS 100 (11), 6505-6510. (Impact Factor 10.3)