Group Leader
Anne Grapin-Botton has a background in developmental and stem cell biology. Her laboratory investigates how the three-dimensional structure of the pancreas is established during fetal life and how this spatial information is integrated with signaling and transcription to control endocrine cell differentiation. To do so, they use mouse genetics, imaging and they developed 3D in vitro culture systems for pancreas progenitors in mouse and human (organoids). These studies enable them to gain insight into human syndromes impairing pancreas development and guide the generation of replacement beta cells for Diabetes therapy.
Education and Career
|
since 2018 |
Director, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany and Research Group Leader, German Center for Diabetes Research / Paul Langerhans Institute Dresden (DZD/PLID) |
|
2012- 2020 |
Professor DanStem, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. |
|
2006 - 2012 |
Assistant Professor at the EPFL (Ecole Polytechnique Fédérale de Lausanne), Lausanne, Switzerland. |
|
2002 - 2005 |
Associate scientist at the ISREC (Swiss Institute for Experimental Cancer Research), Lausanne, Switzerland. |
|
1998 - 2001 |
Post doctoral Fellow. Molecular and Cellular Biology Department, Harvard University, Cambridge, USA. Supervisor: Pr. D. Melton. |
|
1996 - 1998 |
Post doctoral Fellow. Institut d'Embryologie, Nogent-sur-Marne, France. Supervisor: Pr. N. Le Douarin |
|
1995 |
PhD in Molecular and Cellular Pharmacology -University Paris VI, France |