The Center for Membrane Biochemistry and Lipid Research is dedicated to translating fundamental research into clinical applications, with the ultimate goal of leveraging insights for the prevention and treatment of various disorders. At the core of life's foundation, lipids play a pivotal role as structural components in cell membranes and signaling molecules, often implicated in the development of dysfunctions and diseases.

Our researchers aim to comprehensively and systematically understand metabolic diseases, including obesity and diabetes, by uniting diverse scientific disciplines. Employing a range of methodologies, such as analytical, biochemical, biophysical, and computational techniques, alongside disease models and clinical studies, we delve into the intricate realm of lipid function, dysfunction, and interactions with other molecules. This interdisciplinary approach positions us to swiftly and reliably identify the molecular underpinnings of diverse diseases.

Operating at the intersection of scientific advancement and clinical application, our center embraces a translational approach. From preventive measures for metabolic diseases to uncovering novel disease mechanisms and developing/applying innovative therapies, we strive to contribute across the spectrum of medical domains.

As of January 2022, the Center for Membrane Biochemistry and Lipid Research is in its developmental phase, housing the research groups of Prof. Dr. Ünal Coskun, Prof. Dr. Maria Fedorova and Dr. Michal Grzybek. Prof. Coskun's group focuses on membrane biochemistry within the context of cellular signaling, employing an interdisciplinary approach that melds cell biology, synthetic biology, protein biochemistry, structural biology, and biophysics. Dr. Fedorova's research group, "Lipid Metabolism: Analysis and Integration," tackles the complexity and dynamics of lipidomes using cutting-edge techniques such as high-resolution mass spectrometry and bioinformatics. Additionally, they explore the epilipidome and investigate the role of modified lipid molecules in cellular signaling processes.