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AdamTS proteases control basement membrane heterogeneity and organ shape in Drosophila © Dr. Uwe Töpfer
Aug 12, 2024
Our paper “AdamTS proteases control basement membrane heterogeneity and organ shape in Drosophila” has been published in Cell Reports
Dr. Liyuan Sui © Dr. Liyuan Sui
May 02, 2024
Liyuan’s paper “A cellular tilting mechanism important for dynamic tissue shape changes and cell differentiation in Drosophila” has been published in Developmental Cell
Graphical Abstract © Karla Yanín Guerra Santillán
Apr 30, 2024
Yanín's Paper "Elastic Contractile Stress in the Basement Membrane Generates Basal Tension in Epithelia" has been published
Giulia Pierini © Giulia Pierini
Jun 13, 2023
Our paper "Hedgehog morphogen gradient is robust towards variations in tissue morphology in Drosophila" has been published in Scientific Reports
Myosin-II is preferentially recruited to junctions at the AP boundary. Timepoints of a photoconversion experiment using Sqh::Dendra2 show that during initiation of the AP boundary Myosin-II preferentially localizes to the AP boundary. © Dr. Marcus Michel
Feb 27, 2023
Our paper on the local increase of mechanical tension by the regulation of Myosin-II protein localization has been published in Journal of Cell Science
The third edition of the book “Drosophila: Methods and Protocols” has been released. © SpringerNature
Aug 31, 2022
The third edition of the book “Drosophila: Methods and Protocols” has been released.
Summer event © Jing Wang
Jul 07, 2022
Our latest summer event in Spreewald
F-actin staining of Drosophila ovarioles with egg chambers in different stages. Knock-down of either one basement membrane (BM) main component results in a change of BM mechanical properties and changes in the shapes of egg chambers. © Dr. Uwe Töpfer
May 24, 2022
Uwe's paper "Distinct contributions of ECM proteins to basement membrane mechanical properties in Drosophila" has been published
Dr. Elisabeth Fischer-Friedrich and Prof. Christian Dahmann
May 24, 2022
The Fischer-Friedrich Lab and the Dahmann Lab of TU Dresden receive DFG funding to investigate the role of the basement membrane in the morphogenesis of animals