26.09.2024
New Publication - C16-terpenoids from Pseudomonas in Cell Chem. Biol.
Please have a look into our new publication about the Discovery and biosynthesis of non-canonical C16-terpenoids from Pseudomonas in Cell Chemical Biology. This work identifies the gene clusters directing their biosynthesis and reconstitutes their biosynthetic pathways in vitro, revealing that biosynthesis of these C16-terpenoids is performed via a uniform intermediate, with product diversification solely achieved by the terpene synthases.
This paper displays a huge effort containing bioinformatics, enzymology, volatile compound isolation and characterization; significantly expanding the understanding of C16-terpenoid structural space!
Congratulations to Xu-Hua and Qing for this exciting and excellent scientific work!