Heterocyclic polyaromatic hydrocarbons (N/S/O-PAH)
N/S/O-PAHs - sources and potential
Heterocyclic polyaromatic hydrocarbons (PAHs) are a group of thousands of chemicals with heteroatoms in the aromatic ring systems. Heterocyclic PAHs have been frequently detected in the environment along with homocyclic PAHs. Indications of toxicity and environmental abundance of N/S/O-PAHs led to recognition of possible human and environmental hazard posed by heterocyclic PAHs in the last decade. Nevertheless, information on the relevance, occurrence, physicochemical properties and hazards of heterocyclic PAHs is still very scarce.
We are working to change that! Check our insights into environmental hazard of N/S/O-PAHs.
We introduce a novel method for simultaneously assessing the chronic toxicity and bioaccumulation of hydrophobic compounds using Daphnia magna as an alternative to the fish bioaccumulation test. This method enables steady-state to be attained approximately 100 times more quickly, making it ideal for evaluating highly hydrophobic chemicals. Find out more in our open access paper: Daphnia magna as an Alternative Model for (Simultaneous) Bioaccumulation and Chronic Toxicity Assessment─Controlled Exposure Study Indicates High Hazard of Heterocyclic PAHs
This study shows that some (large) heterocyclic PAHs show acute toxic effects only in tests where expousure is adequately controlled (by passived dosing): G. Çelik, S. Stolte, M. Markiewicz, NSO-heterocyclic PAHs–controlled exposure study reveals high acute aquatic toxicity, Journal of Hazardous Materials, 2023, 460. The paper is open access until 28.10.2023
G. Çelik, S. Stolte, S. Müller, F. Schattenberg, M. Markiewicz, Environmental persistence assessment of heterocyclic polyaromatic hydrocarbons-Ultimate and primary biodegradability using adapted and non-adapted microbial communities, Journal of Hazardous Materials, 2023, 460. The paper is open-access until 22.10.2022
Are heterocyclic PAH in the envrionment a reason for concern? Check our preliminary hazard screening in following publication: G. Çelik, S. Beil, S. Stolte, M. Markiewicz Environmental Hazard Screening of Heterocyclic Polyaromatic Hydrocarbons: Physicochemical Data and In Silico Models, Environmental Science & Technology 57 (1), 570-581