Master's Biochemistry
First Semester
BIOLOGICAL CHEMISTRY AND MOLECULAR CELL BIOLOGY
LECTURE
Lecturer: Nils Kröger
When: Mondays at 8:15-9:45
Where: B CUBE E73/74
____________________________________________________________________________________________
GENE EXPRESSION AND MANIPULATION
LECTURE
Lecturer: Nils Kröger
When: Mondays at 10:15-11:45
Where: B CUBE E73/74
SEMINARS
Lecturer: Nicole Poulsen
When: Mondays at 13:00-14:30
Where: B CUBE E73/74
PRACTICAL COURSE
When: January 4th-27th, 2022 (Wed-Fri only)
Where: BIOTEC Teaching Lab
Second Semester
BIOCHEMISTRY OF THE CELL
LECTURE
Lecturer: Nils Kröger
Third Semester
BIOLOGICAL MATERIALS
LECTURE
SEMINAR
PRACTICAL COURSE
____________________________________________________________________________________________
RESEARCH LAB CLASS
During the third semester of the Master program, each student needs to complete a Research Lab Class in one of the groups particpating in the teaching of the Biochemistry Master's program. The lab research project consist of 1 SWS seminar and 15 SWS lab practical.
Projects offered in our group:
01. Diatom Biomineralization
https://tu-dresden.de/cmcb/bcube/forschungsgruppen/kroeger/research/biomineralization
Possible topics include:
- APEX2-based identification of protein-protein interaction networks at the silica deposition vesicles of the model diatom Thalassiosira pseudonana
- Time-lapse fluorescence microscopy imaging of the cytoskeleton during valve silica morphogenesis in the model diatom Thalassiosira pseudonana
- Functional characterization of candidate silica biomineralization proteins through CRISPR-Cas9 mediated gene knockout.
- Identification and functional dissection of the enzyme machinery catalyzing the biosynthesis of long-chain polyamines
02. Diatom Adhesion and Motility
In this project we use a combination of biochemistry, molecular biology and numerous microscopy techniques (e.g. time-lapse, confocal, TIRF, SEM, TEM, AFM) to understand the unusual gliding motility of diatoms. https://tu-dresden.de/cmcb/bcube/forschungsgruppen/kroeger/research/biological-adhesion-and-motility
Possible topics include:
- GFP-tagging and fluorescence microscopy imaging of candidate proteins
in the adhesion-motility complex of the diatom Craspedosaturos australis - Functional characterization of characteristic domains from proteins involved in underwater adhesion of diatoms
- Establishing CRISPR/Cas9 mediated gene knockouts in the model gliding diatoms, Craspedostauros australis
Interested students please send (i) motivation statement, (ii) curriculum vitae, and (iii) transcript of grades by email to Nils Kröger (topic 1) or Nicole Poulsen (topic 2)