Publications

2024

• Optical characterization of molecular interaction strength in protein condensatesBeck, T. A., van der Linden, L., Borcherds, W. M., Kim, K., Schlüßler, R., Müller, P., Franzmann, T. M. & 6 others, Nov 2024, In: Molecular Biology of the Cell. 35, 12, 15 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
• Surviving the heat: the role of macromolecular assemblies in promoting cellular shutdownDesroches Altamirano, C. & Alberti, S., 29 Oct 2024, In: Trends in Biochemical SciencesElectronic (full-text) versionResearch output: Contribution to journal > Review article
• Chemical inhibition of the integrated stress response impairs the ubiquitin-proteasome systemXu, S., Gierisch, M. E., Barchi, E., Poser, I., Alberti, S., Salomons, F. A. & Dantuma, N. P., 8 Oct 2024, In: Communications biology. 7, 1, 1282Electronic (full-text) versionResearch output: Contribution to journal > Research article
• Protocol to reconstitute translationally arrested heat shock mRNPs and condensates in vitroDesroches Altamirano, C. & Alberti, S., 20 Sep 2024, In: STAR Protocols. 5, 3, 103275Electronic (full-text) versionResearch output: Contribution to journal > Research article
• Single-molecule digital sizing of proteins in solutionKrainer, G., Jacquat, R. P., Schneider, M. M., Welsh, T. J., Fan, J., Peter, Q. A., Andrzejewska, E. A. & 8 others, 4 Sep 2024, In: Nature Communications. 15, 1, 7740Electronic (full-text) versionResearch output: Contribution to journal > Research article
• eIF4F is a thermo-sensing regulatory node in the translational heat shock responseDesroches Altamirano, C., Kang, M. K., Jordan, M. A., Borianne, T., Dilmen, I., Gnädig, M., von Appen, A. & 3 others, 2 May 2024, In: Molecular cell. 84 (2024), 9, p. 1727-1741, 27 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
• PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA endsChappidi, N., Quail, T., Doll, S., Vogel, L. T., Aleksandrov, R., Felekyan, S., Kühnemuth, R. & 6 others, 15 Feb 2024, In: Cell. 187 (2024), 4, p. 945-961.e18, 35 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article

2023

• Biomolecular condensates in kidney physiology and diseaseGao, G., Sumrall, E. S., Pitchiaya, S., Bitzer, M., Alberti, S. & Walter, N. G., Dec 2023, In: Nature Reviews. Nephrology. 19, 12, p. 756-770, 15 p.Electronic (full-text) versionResearch output: Contribution to journal > Review article
• Human Small Heat Shock Protein B8 Inhibits Protein Aggregation without Affecting the Native Folding ProcessChoudhary, D., Mediani, L., Avellaneda, M. J., Bjarnason, S., Alberti, S., Boczek, E. E., Heidarsson, P. O. & 4 others, 19 Jul 2023, In: Journal of the American Chemical Society. 145, 28, p. 15188-15196, 9 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
• A shared fate for nuclear and cytosolic inclusionsAlberti, S. & Carra, S., May 2023, In: Nature cell biology. 25, 5, p. 629-630, 2 p.Electronic (full-text) versionResearch output: Contribution to journal > Comment/Debate
• Direct digital sensing of protein biomarkers in solutionKrainer, G., Saar, K. L., Arter, W. E., Welsh, T. J., Czekalska, M. A., Jacquat, R. P. B., Peter, Q. & 11 others, 6 Feb 2023, In: Nature communications. 14, 653Electronic (full-text) versionResearch output: Contribution to journal > Research article

2022

• Cytosolic stress granules relieve the ubiquitin-proteasome system in the nuclear compartmentXu, S., Gierisch, M. E., Schellhaus, A. K., Poser, I., Alberti, S., Salomons, F. A. & Dantuma, N. P., 27 Dec 2022, In: EMBO Journal. 42 (2023), 3, 19 p., e111802Electronic (full-text) versionResearch output: Contribution to journal > Research article
• Biomolecular condensate phase diagrams with a combinatorial microdroplet platformArter, W. E., Qi, R., Erkamp, N. A., Krainer, G., Didi, K., Welsh, T. J., Acker, J. & 10 others, 21 Dec 2022, In: Nature communications. 13, 1, 7845Electronic (full-text) versionResearch output: Contribution to journal > Research article
• SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNAMaharana, S., Kretschmer, S., Hunger, S., Yan, X., Kuster, D., Traikov, S., Zillinger, T. & 16 others, 6 Oct 2022, In: Molecular cell. 82, 19, p. 3712-3728.e1-e10, 28 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
• CAPRIN1^P512L causes aberrant protein aggregation and associates with early-onset ataxiaDelle Vedove, A., Natarajan, J., Zanni, G., Eckenweiler, M., Muiños-Bühl, A., Storbeck, M., Guillén Boixet, J. & 10 others, Oct 2022, In: Cellular and Molecular Life Sciences. 79, 10, 526Electronic (full-text) versionResearch output: Contribution to journal > Research article
• Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutionsKar, M., Dar, F., Welsh, T. J., Vogel, L. T., Kühnemuth, R., Majumdar, A., Krainer, G. & 6 others, 12 Jul 2022, In: Proceedings of the National Academy of Sciences of the United States of America : PNAS. 119, 28, e2202222119Electronic (full-text) versionResearch output: Contribution to journal > Research article
• Correlative all-optical quantification of mass density and mechanics of sub-cellular compartments with fluorescence specificitySchlüßler, R., Kim, K., Nötzel, M., Taubenberger, A., Abuhattum, S., Beck, T., Müller, P. & 6 others, 10 Jan 2022, In: eLife. 11, 23 p., e68490Electronic (full-text) versionResearch output: Contribution to journal > Research article
• Surface Electrostatics Govern the Emulsion Stability of Biomolecular CondensatesWelsh, T. J., Krainer, G., Espinosa, J. R., Joseph, J. A., Sridhar, A., Jahnel, M., Arter, W. E. & 4 others, 10 Jan 2022, In: Nano letters. 22, 2, p. 612-621, 10 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article

2021

• Mapping Tumor Spheroid Mechanics in Dependence of 3D Microenvironment Stiffness and Degradability by Brillouin MicroscopyMahajan, V., Beck, T., Gregorczyk, P., Ruland, A., Alberti, S., Guck, J., Werner, C. & 2 others, 1 Nov 2021, In: Cancers. 13, 21, 5549Electronic (full-text) versionResearch output: Contribution to journal > Research article
• Quantitative proteomics identifies the universally conserved ATPase Ola1p as a positive regulator of heat shock response in Saccharomyces cerevisiaeDannenmaier, S., Altamirano, C. D., Schueler, L., Zhang, Y., Hummel, J., Milanov, M., Oeljeklaus, S. & 4 others, Nov 2021, In: Journal of Biological Chemistry. 297, 5, 101050Electronic (full-text) versionResearch output: Contribution to journal > Research article
• Adaptable P body physical states differentially regulate bicoid mRNA storage during early Drosophila developmentSankaranarayanan, M., Emenecker, R. J., Wilby, E. L., Jahnel, M., Trussina, I. R. E. A., Wayland, M., Alberti, S. & 2 others, 25 Oct 2021, In: Developmental cell. 56, 20, p. 2886-2901, 16 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
• Ubiquitin protein helps cells to recover from stressFranzmann, T. & Alberti, S., 9 Sep 2021, In: Nature. 597, 7875, p. 183-184, 2 p.Electronic (full-text) versionResearch output: Contribution to journal > Comment/Debate
• HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA-binding domainBoczek, E. E., Fursch, J., Niedermeier, M. L., Jawerth, L., Jahnel, M., Ruer-Gruss, M., Kammer, K. & 12 others, 6 Sep 2021, In: eLife. 2021, 10, e69377Electronic (full-text) versionResearch output: Contribution to journal > Research article
• Publisher Correction: Reciprocal regulation of cellular mechanics and metabolism (Nature Metabolism, (2021), 3, 4, (456-468), 10.1038/s42255-021-00384-w)Evers, T. M. J., Holt, L. J., Alberti, S. & Mashaghi, A., Jun 2021, In: Nature metabolism. Vol. 3. p. 876-877, 2 p.Electronic (full-text) versionResearch output: Contribution to specialist publication > Corrections (errata and retractions)
• Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptorTiago, T., Hummel, B., Morelli, F. F., Basile, V., Vinet, J., Galli, V., Mediani, L. & 17 others, 6 May 2021, In: Cell death and disease. 12, 5, 452Electronic (full-text) versionResearch output: Contribution to journal > Research article