Services
The facility's aim is to provide internal and external users a broad range of services based on its long-standing and diverse expertise in the development, manufacture and therapeutic use of advanced-therapy medicinal products (ATMP) and tissue engineering products (TEP) and their regulatory drug approval.
The GMP core offers a unique infrastructure for applied biomedical research: GMP-conform production sites with state-of-the-art equipment as well as medico-legal competence.
Due to the long lasting, sound expertise within this cluster we were already able to implement standard operating procedures (SOPs) for the generation of GMP-grade Mesenchymal Stromal Cells (MSC), regulatory T-lymphocytes (Treg) and virus-specific T-lymphocytes.
Implemented protocols and cell types
Cell type | Application |
allogeneic Mesenchymal stromal cells from bone marrow (BM-MSC) and umbilical cord (UC-MSC) | - Graft-versus-Host-Disease (GvHD) |
Regulatory T-lymphocytes (Treg) | - autoimmune diseases |
virus-specific T-lymphocytes | - transplantation-associated viral infections |