Publications
2023
Seeding the meiotic DNA break machinery and initiating recombination on chromosome axes.
Dereli I, Telychko V, Papanikos F, Raveendran K, Xu J, Boekhout M, Stanzione M, Neuditschko B, Imjeti NS, Selezneva E, Erbasi HT, Demir S, Giannattasio T, Gentzel M, Bondarieva A, Stevense M, Barchi M, Schnittger A, Weir JR, Herzog F, Keeney S, Tóth A.
bioRxiv. 2023 Nov 27:2023.11.27.568863. doi: 10.1101/2023.11.27.568863
Wie man ein Glashaus baut: die außergewöhnlichen Proteine der Kieselalgen
Kröger N & Gentzel M.
Biospektrum 06.23 doi: 10.1007/s12268-023-2031-7
Obatoclax Rescues FUS-ALS Phenotypes in iPSC-Derived Neurons by Inducing Autophagy.
Castillo Bautista CM, Eismann K, Gentzel M, Pelucchi S, Mertens J, Walters HE, Yun MH, Sterneckert J.
Cells. 2023 Sep 11;12(18):2247. doi: 10.3390/cells12182247
Biomimetic Protocells Featuring Macrophage-Like Capture and Digestion of Protein Pathogens.
Xu X, Moreno S, Gentzel M, Zhang K, Wang D, Voit B, Appelhans D.
Small Methods. 2023 Aug 20:e2300257. doi: 10.1002/smtd.202300257
2022
Dickkopf1 fuels inflammatory cytokine responses.
Jaschke NP, Pählig S, Sinha A, Adolph TE, Colunga ML, Hofmann M, Wang A, Thiele S, Schwärzler J, Kleymann A, Gentzel M, Tilg H, Wielockx B, Hofbauer LC, Rauner M, Göbel A, Rachner TD.
Commun Biol. 2022 Dec 20;5(1):1391. doi: 10.1038/s42003-022-04368-8
Proteomic consequences of TDA1 deficiency in Saccharomyces cerevisiae: Protein kinase Tda1 is essential for Hxk1 and Hxk2 serine 15 phosphorylation.
Müller H, Lesur A, Dittmar G, Gentzel M, Kettner K.
Sci Rep. 2022 Oct 27;12(1):18084. doi: 10.1038/s41598-022-21414-x
SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA.
Maharana S, Kretschmer S, Hunger S, Yan X, Kuster D, Traikov S, Zillinger T, Gentzel M, Elangovan S, Dasgupta P, Chappidi N, Lucas N, Maser KI, Maatz H, Rapp A, Marchand V, Chang YT, Motorin Y, Hubner N, Hartmann G, Hyman AA, Alberti S, Lee-Kirsch MA.
Mol Cell. 2022 Oct 6;82(19):3712-3728.e10. doi: 10.1016/j.molcel.2022.08.031
C11orf94/Frey is a key regulator for male fertility by controlling Izumo1 complex assembly.
Contreras W, Wiesehöfer C, Schreier D, Leinung N, Peche P, Wennemuth G, Gentzel M, Schröder B, Mentrup T.
Sci Adv. 2022 Aug 12;8(32):eabo6049. doi: 10.1126/sciadv.abo6049
LShedding light on silica biomineralization by comparative analysis of the silica-associated proteomes from three diatom species.
Skeffington AW, Gentzel M, Ohara A, Milentyev A, Heintze C, Böttcher L, Görlich S, Shevchenko A, Poulsen N, Kröger N
Plant J. 2022 Jun;110(6):1700-1716. doi: 10.1111/tpj.15765
2021
Listening to the Whispers in Neuroimmune Crosstalk: A Comprehensive Workflow to Investigate Neurotrophin Receptor p75NTR Under Endogenous, Low Abundance Conditions.
Dorschner BW, Wiedemuth R, Funke AC, Gentzel M, Rogers ML, Brenner S, Thieme S.
Front Immunol. 2021 Apr 16;12:648283. doi: 10.3389/fimmu.2021.648283
2019
Auto-regulation of Rab5 GEF activity in Rabex5 by allosteric structural changes, catalytic core dynamics and ubiquitin binding.
Lauer, J., Segeletz, S., Cezanne, A., Guaitoli, G., Raimondi, F., Gentzel, M., Alva, V., Habeck, M., Kalaidzidis, Y., Ueffing, M., Lupas, A.N., Gloeckner, C.J., Zerial, M.
Elife. 2019 Nov 13;8:e46302. doi: 10.7554/eLife.46302.
Proteomic navigation using proximity-labeling.
Gentzel, M., Pardo, M., Subramaniam, S., Stewart, A.F., Choudhary, J.S.
Methods. 2019 Jul 15;164-165:67-72. doi: 10.1016/j.ymeth.2019.03.028. Epub 2019 Apr 4.
2018
Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo.
Kotini, M., Barriga, E.H., Leslie, J., Gentzel, M., Rauschenberger, V., Schambony, A., Mayor, R.
Nat Commun. 2018 Sep 21;9(1):3846. doi: 10.1038/s41467-018-06368-x.
Pgam5 released from damaged mitochondria induces mitochondrial biogenesis via Wnt signaling
Bernkopf, D.B., Jalal, K., Brückner, M., Knaup, K.X., Gentzel, M., Schambony, A., Behrens, J.
J Cell Biol. 2018 Apr 2;217(4):1383-1394. doi: 10.1083/jcb.201708191. Epub 2018 Feb 8.
MS Western, a Method of Multiplexed Absolute Protein Quantification is a Practical Alternative to Western Blotting
Kumar, M., Joseph, S.R., Augsburg, M., Bogdanova, A., Drechsel, D., Vastenhouw, N.L., Buchholz, F., Gentzel, M., Shevchenko, A.
Mol Cell Proteomics. 2018 Feb;17(2):384-396. doi: 10.1074/mcp.O117.067082. Epub 2017 Nov 30.
2017
The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning
Rauschenberger, V., Bernkopf, D.B., Krenn, S., Jalal, K., Heller, J., Behrens, J., *Gentzel, M., *Schambony, A.
Development. 2017 Jun 15;144(12):2234-2247. doi: 10.1242/dev.144477. Epub 2017 May 15.
Dishevelled Paralogs in Vertebrate Development: Redundant or Distinct?
Gentzel, M., Schambony, A.
Front Cell Dev Biol. 2017 May 26;5:59. doi: 10.3389/fcell.2017.00059. eCollection 2017. Review.
Serum Proteases Potentiate BMP-Induced Cell Cycle Re-entry of Dedifferentiating Muscle Cells during Newt Limb Regeneration
Wagner, I., Wang, H., Weissert, P.M., Straube, W.L., Shevchenko, A., Gentzel, M., Brito, G., Tazaki, A., Oliveira, C., Sugiura, T., Shevchenko, A., Simon, A., Drechsel, D.N., Tanaka, EM.
Dev Cell. 2017 Mar 27;40(6):608-617.e6. doi: 10.1016/j.devcel.2017.03.002.
2015
Distinct functionality of Dishevelled isoforms on Ca2+/Calmodulin dependent protein kinase 2 (CamKII) in Xenopus gastrulation
*Gentzel, M., *Schille, C., Rauschenberger, V., Schambony, A.
Mol Biol Cell. 2015 Mar 1;26(5):966-77. doi: 10.1091/mbc.E14-06-1089. Epub 2015 Jan 7.
2014
β-Arrestin interacts with the beta/gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2+) pathway in xenopus gastrulation
Seitz, K., Dürsch, V., Harnoš, J., Bryja, V., Gentzel, M., Schambony, A.
PLoS One. 2014 Jan 29;9(1):e87132. doi: 10.1371/journal.pone.0087132. eCollection 2014