Dr.-Ing. Jiawei Sun, postdoc at the Chair of Measurement and Sensor System Technique (Czarske Lab), is awarded the prestigious Dr.-Ing. Siegfried Werth Prize for his outstanding dissertation on "Learning-based Three-Dimensional Optical Cell Rotation Tomography and Quantitative Phase Imaging Using Multi-Core Fibers". Since 1988, the Dr.-Ing. Siegfried Werth Foundation has awarded the prize annually for scientific work in the field of non-contact dimensional measurement technology. The prize is donated with 1,500 euros.

In order to diagnose disease-related changes in biological cells and tissues, image data of the patient's organs and structures are nowadays provided with the help of a wide variety of apparative examination methods, such as computer tomography or magnetic resonance imaging. Despite significant breakthroughs in the field of optical imaging of biological samples, research in this area remains very active. Scientists worldwide are trying to surpass current spatial and temporal resolution, contrast and quantitative capabilities, especially by incorporating fibre optic techniques into minimally invasive endoscopy.

In his dissertation, Dr.-Ing. Sun investigated for the first time a multinuclear fibre-based double-beam trap that enables digitally program-controlled three-dimensional cell rotation using area light modulators. He used an autonomous tomographic reconstruction workflow based on computer vision technologies and machine learning (including physics-informed deep learning) for a robust three-dimensional tomographic reconstruction of the rotated cell.

"Dr.-Ing. Jiawei Sun has done pioneering work on the non-contact rotation and examination of cancer cells, thus enabling a transfer to biomedical applications. The latest methods of artificial intelligence were introduced for fibre endoscopic tomography procedures for the first time and used for image processing and image generation," explains Prof. Jürgen Czarske, doctoral supervisor of the award winner and holder of Chair of Measurement and Sensor System Technique.

"I am very pleased to receive the award from the Dr.-Ing. Siegfried Werth Foundation and feel honoured. The award encourages me to further intensify my research in the field of optical imaging and to improve existing investigation methods with the help of artificial intelligence and deep learning," says Dr.-Ing. Jiawei Sun.

Dr.-Ing. Sun's research offers innovative methods for optical manipulation, tomography and fibre endoscopic imaging with nanometre resolution and opens new perspectives for future applications in biomedicine and microelectronics with minimally invasive keyhole access.

Contact:
Dr.-Ing. Jiawei Sun
Dresden University of Technology
Faculty of Electrical Engineering and Information Technology
Chair of Measurement and Sensor System Technique
jiawei.sun@tu-dresden.de