Perfusion Technology Group

We are looking for a student assistant (10 h/week) for the summer semester 2023 to support the teaching. The work time is 10 hours/week. The specific timeslot can be adjusted according to your schedule. The duration of employment is in accordance with the WissZeitVG.

Tasks:

•     Support in the preparation and execution of tests on medical devices.
•     Support in the preparation and execution of experiments
•     Construction of accessories for measuring stations
•     Processing of 3D printing orders.

Requirements:

•     Matriculation at a university
•     Knowledge of CAD (preferably Inventor)
•     Interest in working in a medical environment
•     Very good knowledge of the German language.

Please submit your application documents with CV and current overview of grades by e-mail to:

Ms Dr.-Ing. Susanne Kromnik
susanne.kromnik@tu-dresden.de

• Subject area: ECMO applications

  Support with extracorporeal membrane oxygenation is a Rescue-Procedure, when invasive ventilation can no longer guarantee the oxygen-supply via the lungs. ECMO therapy ranges from an application of a few hours to several weeks. The crucial element of ECMO is the oxygenator. This is where oxygenation takes place and carbon dioxide is eliminated from the blood. The functionality of this component in the ECMO system is critical.

  • Analysis of oxygenator concepts for ECMO
  • Evaluation of the oxygenator in long-term ECMO application
  • Analysis of control strategies during extracorporeal life support
  • Research and analysis of concepts for patient safety in ECMO
  • Analysis of sensor concepts for determination of respiratory gas composition
  • Sensor concepts for determining the flow rate and direction of respiratory gases
  • Analysis of machine learning concepts for application in ECMO
  • Analysis of online blood gas monitoring systems during extracorporeal support
• Subject area: 3D printing for medical technology
  Additive manufacturing of components is a fast and cost-effective method for the production of small series. This process is also increasingly used in the field of medical technology.
  • Analysis of silicone 3D printing processes for medical technology
• Subject area: blood glucose regulation
  If the natural blood glucose regulation of humans is disturbed, technical devices can be used to control the blood glucose level. In the field of automated blood glucose control, new strategies and concepts for implementation have been researched, especially in recent years.
  • Analysis of blood glucose control strategies

Individual topic suggestions on current topics of the working group are possible at any time.

Topics for student research projects and diploma theses include:

• Development of device components and control strategies for extracorporeal membrane oxygenation (ECMO)
  • Conceptual design of an evaluation of the oxygenator in ECMO application
• Development of device concepts for ex vivo organ perfusion
  • Further development of the organ storage based on existing concepts
  • Conceptual design and development of an emergency power system
  • Development of components for the controlled oxygenated reperfusion (COR) of donor kidneys for NMP

  • Evaluation of existing data sets (blood data, perfusion data, image data) with regard to existing standards

  • Further development of existing topology concepts with regard to optimized usability

• Research in the field of 3D printing for medical technology
  • Conceptual design of in-process quality assurance methods for 3D printing
  •  Optimization and modularization of an existing silicone 3D printing system
• Investigation of oxygen enrichment in air vehicles during high-flow oxygen therapy

Our partners offer the following topics or positions:

VIVE-Medtech

• Open positions at VIVE-Medtech

Pulmonary Engineering Group, Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine Carl Gustav Carus

• Identification of recruitable areas in the thorax computed tomogram using deep neural networks
• Modeling of overventilated lung tissue and determination of lung volumes in the computed tomogram
• Comparative modeling of nonlinear respiratory mechanics with respect to dependence on airway flow

Organ models
In surgical training of minimally invasive procedures, the use of animal organs should be avoided. This requires the provision of technical models to simulate human physiology. The Institute of Biomedical Engineering at the Technical University of Dresden has developed innovative organ phantoms of the gastrointestinal tract, including the liver and gall bladder, in cooperation with the Research Institute for Leather and Plastic Sheeting FILK in Freiberg and the Research Group for Minimally Invasive Interdisciplinary Therapeutic Intervention (MITI) at the Technical University of Munich. These are characterised by a realistic appearance (shape, size, colour, texture) and haptics (weight, viscosity, elasticity) as well as by their suitability for surgical preparation methods such as sharp or electrocautery cutting, clipping, grasping, injecting, suturing, stapling and for display in imaging procedures. The developed collagen-based organ phantoms were integrated into an ELITE surgical phantom to provide a training unit for various applications, e.g. cholecystectomy (removal of the gallbladder).

© IBMT/Thiele

• Optimisation of perfusion for extracorporeal membrane oxygenation (ECMO)
• Extracorporeal perfusion of kidneys

Hyperspectral imaging for the assessment of organ status during perfusion.