Projects 2nd period
Description of the dissertation projects in the 2nd pERIOD
In the second phase, the following dissertation projects will be processed:
No. |
Project name |
Supervisor |
Co-supervisor | ||||
A |
Materials and processes |
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A3 |
A3: Representation of hydrogel building blocks with defined swelling behaviour |
Fery /Thiele |
Wallmersperger |
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Microfluidic representation of hydrogel particles with defined shape and composition as well as quantification of the swelling properties by AFM force spectroscopy on single particle level. |
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A4 |
A4: Phase transitions in gel systems and their dependence on mechanical loads |
Odenbach |
Fery |
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On the basis of the previous investigations on gel formation under load and the current work on the definition of the gel point, experiments on different gel systems will be carried out to investigate the dependence of gel parameters on load influence. |
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A5 |
Odenbach |
Gerlach |
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Microstructural investigations will be conducted to determine the causes of magnetic control and to develop concepts for an application-specific adaptation of the properties of magnetorheological hydrogels. |
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A6 |
A6: Structure of enzymatic reaction cascades in/at hydrogels in microfluidic processes |
Voit (Appelhans) |
Richter/Günther |
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Non-covalent and bioconjugated fixation of enzymes to and in hydrogel surfaces will be used to establish enzymatic reaction cascades in microfluidic processes. |
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A7 |
Voit (Zschoche) |
Richter/Gerlach |
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Realization of bisensitive hydrogels for microsystems with high sensitivity, selectivity and stability by the design of structure and morphology of the polymer segments. |
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A8 |
Wallmersperger |
Voit (Zschoche)/Richter/Fery |
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Sensitive two- and multi-layer component hydrogels are investigated and modelled and numerically simulated with respect to the coupled chemo-mechanical behavior depending on different stimulation. |
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A9 |
A9: Optical structuring of microscale polymer systems |
Thiele | Appelhans/Richter | ||||
Adjustment of local material properties of light-switchable microgels using additive methods to build up defined reaction spaces in cell biology and cell-free biotechnology. |
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B |
Microsystems |
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B1 |
Günther (Härtling) |
Gerlach | |||||
Realisation of a parallel optical measurement of temperature, pH-value and ethanol content in a sensor head with corresponding sensitive hydrogels immobilised on the plasmon sensor surface for use in the food industry. |
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B2 |
B2: Hydrogel-based bioaffinity sensor for the detection of biomolecules |
Günther |
Gerlach/Voit |
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Development of a biosensor for the blood coagulation factor thrombin for applications in medical diagnostics and therapy. The aim is to develop aptamer hydrogels that specifically and reversibly bind thrombin. |
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B3 |
B3: Hydrogel-based sensor switches with switching hysteresis |
Gerlach |
Wallmersperger |
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Hydrogels are to be used as material for the switching element in powerless sensor switches, which are of particular interest for energy self-sufficient systems. The switching hysteresis and the switching kinetics of the hydrogel are of particular importance. |
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B4 |
B4: Modelling and simulation of a force compensated piezoresistive chemosensor on hydrogel basis |
Wallmersperger |
Gerlach/ Günther |
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By means of modeling by a coupled chemo-electro-mechanical multi-field formulation, based on the finite element method, it shall be investigated how fast and exactly a sensor with applied counterforce responds in a defined swollen state. |
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B5 |
Richter (Marschner) |
Wallmersperger | |||||
The aim is to understand the nature of hydrogel-based devices with (a) storage and discretization functions in discontinuous microfluidic systems and (b) integratable hydrogel-based MEMS components for circuits and integrated circuits. | |||||||
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Richter |
Voit (Appelhans) |
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The aim is to develop scalable concepts for highly integrated microfluidic MEMS circuits based on hydrogellactors. This includes the development of device concepts, suitable chip architectures and control concepts. The work is based on freely programmable tactile foil displays and specific Labs-on-Chip. |
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B7 |
B7: Force-compensated piezoresistive pH sensors on hydrogel basis |
Gerlach | Voit (Zschoche)/Wallmersperger | ||||
The combination of a pH-sensitive pressure sensor and a temperature-sensitive actuator should lead to a force-compensated pH sensor with significantly improved accuracy and response time. The use of interpenetrating networks of pH- and temperature-sensitive hydrogel allows sensor and actuator function to be combined, which allows a significantly simplified design. |