Prof. Dr. rer. nat. habil. Kathrin Barth
|
Dependent PI of “Neurobiology” at the Institute for Anatomy, Medical Faculty Carl Gustav Carus, TU-Dresden |
Qualifications and Career
|
since 01/2023 |
Dependent PI of “Neurobiology”, Institute for Anatomy, Medical Faculty Carl Gustav Carus, TU-Dresden |
|
08/2022 |
Appointed as extraordinary professor of Anatomy (apl. Prof.), Medical Faculty Carl Gustav Carus, TU-Dresden |
|
since 2016 |
Lecturer of macroscopic and microscopic anatomy in the studies of human medicine |
|
2015 |
Awarded the titles Privatdozent (lecturer) and Dr. rer. nat. habil., Medical Faculty Carl Gustav Carus, TU-Dresden |
| 2015 | Habilitation and venia legendi in Anatomy, Medical Faculty Carl Gustav Carus, TU- Dresden |
|
2008 - 2019 |
Independent PI of “Molecular mechanisms of lung damage” Institute for Anatomy, Medical Faculty Carl Gustav Carus, TU-Dresden (Director: Prof. Richard Funk) |
|
2002 - 2008 |
Postdoctoral fellow,
Institute for Anatomy, Medical Faculty Carl Gustav Carus, TU-Dresden with focus in pulmonary fibrosis (Supervisor: Prof. Michael Kasper) |
| 2001 |
Awarded the title Dr. rer. nat. (PhD) with magna cum laude |
|
1998 – 2001 |
PhD thesis, Institute for Genetics, Faculty of Mathematics and Natural Sciences, TU Dresden Dissertation: „Molecular and biochemical characterization of the mitochondrial translation activator Cbs2p in Saccharomyces cerevisiae“ |
| 1998 | Awarded the "Lohrmann Medal", TU Dresden (for the best graduates of a year). |
|
1994 - 1998 |
Studies of Biology, Faculty of Mathematics and Natural Science, TU-Dresden |
FUNDING
2020 – 2022 DFG renewal application BA 3899/4-2
2017 – 2019 DFG „The role of alveolar type I cells in bleomycin-induced lung injury: elucidation of fibrosis-relevant signaling pathways“, BA 3899/4-1
2008 - 2010 Wilhelm Sander Foundation „Studies on the role of caveolin-1 in the bleomycin-induced, senescence-triggering signaling cascades in tumor cells“
2006 - 2007 Wilhelm Sander Foundation „Studies on signal transduction in epithelial cells of the lung and on the expression of caveolin-1 in tumor cells after damage by bleomycin“
Teaching activities
since 2016 Full pre-clinical teaching in the field of microscopic and macroscopic anatomy in the studies of human medicine
2010 - 2015 Pre-clinical teaching in the field of microscopic anatomy and general anatomy
2011 - 2020 Boston University at TU Dresden: Engineering program “Course on General Histology”
Peer-reviewed publications (selection of 10)
Publications as First and last author
- Kathrin Barth, Verica Vasić, Brennan McDonald, Nora Heinig, Marc-Christoph Wagner, Ulrike Schumann, Cora Rohlecke, Frank Bicker, Lana Schumann, Konstantin Radyushkin, Jan Baumgart, Stefan Tenzer, Frauke Zipp, Matthias Meinhardt, Kari Alitalo, Irmgard Tegeder & Mirko HH Schmidt (2023) EGFL7 loss correlates with increased VEGF-D expression, upregulating hippocampal adult neurogenesis and improving spatial learning and memory. Cell Mol Life Sci 80 (2), 54.
- Viktoria Menzel1#, Matthias Ziegler1#, Miriam Müller1, Nadhim Kamil Hante2,3, Johannes A. Sake2, Maria Jose Santos-Martinez2, Carsten Ehrhardt2,*, Michael Kasper1, Kathrin Barth1,* (2022) Bleomycin causes Fyn-kinase-dependent reduction in alveolar epithelial E-cadherin and caveolin-1 expression. Eur J Pharm Sci 175:106236
- Vasic V, Barth K, Schmidt MHH (2019) Neurodegeneration and Neuro-Regeneration-Alzheimer's Disease and Stem Cell Therapy. Int J Mol Sci 20(17):1-21
- Wesslau KP, Stein A, Kasper M, Barth K (2019) P2X7 Receptor Indirectly Regulates the JAM-A Protein Content via Modulation of GSK-3β. Int J Mol Sci 20(9):197-210
- Heupel J, Bläsche R, Wesslau KP, Kasper M, Barth K. (2018) P2X7R: independent modulation of aquaporin 5 expression in CdCl2-injured alveolar epithelial cells. Histochem Cell Biol 149(3):197-208
- Kasper M, Barth K (2017) Potential contribution of alveolar epithelial type I cells to pulmonary fibrosis. Biosci Rep 37(6):1-18
- Barth K, Bläsche R, Neißer A, Bramke S, Frank JA, Kasper M (2016) P2X7R-dependent regulation of glycogen synthase kinase 3β and claudin-18 in alveolar epithelial type I cells of mice lung. Histochem Cell Biol 146(6):757-768
- Hofmann F, Bläsche R, Kasper M,and Barth K (2015) A co-culture system with an organotypic lung slice and an immortal alveolar macrophage cell line to quantify silica-induced inflammation. PLoS One 10(1):e0117056
- Ebeling G, Bläsche R, Hofmann F, Augstein A, Kasper M, Barth K (2014) Effect of P2X7 receptor knockout on AQP-5 expression of type I alveolar epithelial cells. PLoS One 9(6):e100282
- Bläsche R, Ebeling G, Perike S, Weinhold K, Kasper M, Barth K (2012) Activation of P2X7R and downstream effects in bleomycin treated lung epithelial cells. Int J Biochem Cell Biol 44(3):514-24
BIBLIOGRAPHY
Publications: 40
First authorships: 29
Last authorships: 11
INVITED PRESENTATIONS – INTERNATIONAL (2016-)
- 2017 Annual Congress of the European Respiratory Society Milan, Italy
- 2017 Keystone Symposium: Injury, Inflammation and Fibrosis Salt Lake City, USA
- 2018 The 8th Annual World Congress of Molecular & Cell Biology, Fukuoka, Japan
- 2019 1st European Purine Meeting, Santiago de Compostela, Spain