Prof. Dr. rer. nat. habil. Kathrin Barth

Qualifications and Career

FUNDING

2020 – 2022    DFG renewal application BA 3899/4-2

2017 – 2019   DFG „The role of alveolar type I cells in bleomycin-induced lung injury: elucidation of fibrosis-relevant signaling pathways“, BA 3899/4-1

2008 - 2010    Wilhelm Sander Foundation „Studies on the role of caveolin-1 in the bleomycin-induced, senescence-triggering signaling cascades in tumor cells“

2006 - 2007    Wilhelm Sander Foundation „Studies on signal transduction in epithelial cells of the lung and on the expression of caveolin-1 in tumor cells after damage by bleomycin“

Teaching activities

since 2016      Full pre-clinical teaching in the field of microscopic and macroscopic anatomy in the studies of human medicine

2010 - 2015    Pre-clinical teaching in the field of microscopic anatomy and general anatomy

2011 - 2020    Boston University at TU Dresden: Engineering program “Course on General Histology”

Peer-reviewed publications (selection of 10)

Publications as First and last author

• Kathrin Barth, Verica Vasić, Brennan McDonald, Nora Heinig, Marc-Christoph Wagner, Ulrike Schumann, Cora Rohlecke, Frank Bicker, Lana Schumann, Konstantin Radyushkin, Jan Baumgart, Stefan Tenzer, Frauke Zipp, Matthias Meinhardt, Kari Alitalo, Irmgard Tegeder & Mirko HH Schmidt (2023) EGFL7 loss correlates with increased VEGF-D expression, upregulating hippocampal adult neurogenesis and improving spatial learning and memory. Cell Mol Life Sci 80 (2), 54.
• Viktoria Menzel^1#, Matthias Ziegler^1#, Miriam Müller¹, Nadhim Kamil Hante^2,3, Johannes A. Sake², Maria Jose Santos-Martinez², Carsten Ehrhardt^2,*, Michael Kasper¹, Kathrin Barth^1,* (2022) Bleomycin causes Fyn-kinase-dependent reduction in alveolar epithelial E-cadherin and caveolin-1 expression. Eur J Pharm Sci 175:106236
• Vasic V, Barth K, Schmidt MHH (2019) Neurodegeneration and Neuro-Regeneration-Alzheimer's Disease and Stem Cell Therapy. Int J Mol Sci 20(17):1-21
• Wesslau KP, Stein A, Kasper M, Barth K (2019) P2X7 Receptor Indirectly Regulates the JAM-A Protein Content via Modulation of GSK-3β. Int J Mol Sci 20(9):197-210
• Heupel J, Bläsche R, Wesslau KP, Kasper M, Barth K. (2018) P2X7R: independent modulation of aquaporin 5 expression in CdCl₂-injured alveolar epithelial cells. Histochem Cell Biol 149(3):197-208
• Kasper M, Barth K (2017) Potential contribution of alveolar epithelial type I cells to pulmonary fibrosis. Biosci Rep 37(6):1-18
• Barth K, Bläsche R, Neißer A, Bramke S, Frank JA, Kasper M (2016) P2X7R-dependent regulation of glycogen synthase kinase 3β and claudin-18 in alveolar epithelial type I cells of mice lung. Histochem Cell Biol 146(6):757-768
• Hofmann F, Bläsche R, Kasper M,and Barth K (2015) A co-culture system with an organotypic lung slice and an immortal alveolar macrophage cell line to quantify silica-induced inflammation. PLoS One 10(1):e0117056
• Ebeling G, Bläsche R, Hofmann F, Augstein A, Kasper M, Barth K (2014) Effect of P2X7 receptor knockout on AQP-5 expression of type I alveolar epithelial cells. PLoS One 9(6):e100282
• Bläsche R, Ebeling G, Perike S, Weinhold K, Kasper M, Barth K (2012) Activation of P2X7R and downstream effects in bleomycin treated lung epithelial cells. Int J Biochem Cell Biol 44(3):514-24

BIBLIOGRAPHY

Publications: 40

First authorships: 29

Last authorships: 11

INVITED PRESENTATIONS – INTERNATIONAL (2016-)

• 2017 Annual Congress of the European Respiratory Society Milan, Italy
• 2017 Keystone Symposium: Injury, Inflammation and Fibrosis Salt Lake City, USA
• 2018 The 8th Annual World Congress of Molecular & Cell Biology, Fukuoka, Japan
• 2019 1st European Purine Meeting, Santiago de Compostela, Spain