Project B20
Targeting ferroptosis in adrenocortical carcinoma (ACC): from basic mechanisms to novel treatments
Aims
(I) Explore the function and therapeutic potential of FSP1 in ACC
(II) Elucidate selenium uptake and metabolism in adrenocortical cells in order to develop treatment strategies mimicking GPX4 inhibition.
(III) Characterise the immunomodulatory effects of ferroptosis in ACC
Principal Investigators | Institution |
Prof. Dr. med. Dr. rer. nat. Matthias Kroiss | LMU |
Prof. Dr. José Pedro Friedmann-Angeli | JMU |
LMU |