Tissue samples
The Tumor and Normal Tissue Bank (TNTB) is a central tissue biobank in which solid tumor tissue is stored. The TNTB is affiliated to the Institute of Pathology and is certified in accordance with DIN EN ISO 9001:2015.
Overview of our range of services
- Preservation of fresh tissue for TNTB or for studies (Tumor tissue, normal tissue)
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Production of FFPE tissue blocks
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Production of tissue microarray tissue blocks
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Production of slides with tissue sections of:
Fresh tissue/cryo tissue, FFPE tissue blocks
Information on requirements & procedure
Tissue preservation - Institute of Pathology
- Monday to Friday: 09:00 to 16:30 (technical assistance)
if samples are received later in the pathology department: Asservation by the person on duty if time permits
The preservation of tissue samples in the TNTB is only possible with valid patient consent. Consent is usually given on the basis of the Broad Concent.
Notes on the "Specimen accompanying document - Pathology":
Each tissue sample that is sent to the Institute of Pathology of the UKD for diagnostic questions and for tissue preservation must be accompanied by a correctly and completely filled out sample accompanying form. The following additional information is required for preservation in the TNTB:
(A stamp for simplified documentation can be ordered in SAP).
If you are interested in samples, you can access various collections and services. Please contact us and we will be happy to advise you.
We will first check that all the necessary information has been submitted and that the requested samples are available. Depending on who is the collection manager and which collection is involved, the approval procedure for sample submission is designed.
The request for broad-consent samples from the BBD takes place in a multi-stage procedure. Within one week, the application form is forwarded by circulation to the BioBank Dresden utilization and allocation committee, consisting of medical specialists and scientists. The committee decides on the approval of the application within 10 working days. . As soon as a result of the vote is available, the applicant will be informed in writing.
Application procedure
- When submitting a TNTB project application, please attach a copy of the supporting ethics vote.
- If FFPE samples younger than 3 years are to be used for a research project explicitly selected by the project leader, the project leader is obliged to check whether the relevant patients have consented to the use of their sample material for research (EWEs must be filed in ORBIS) and to note this in the sample list attached to the project.
Current tissue material (FFPE material younger than 3 years) from patients who have not consented to the use of their material for research may not be used.
General information
All applications should include the following information
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short project description (approx. half a DIN A4 page)
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Details of the specific tissue request (type and number)
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Details of cooperation partners
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Information on the project-related ethics vote
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Information on project financing / invoice address
Please send us all signed documents to: Mail
Sample collection and telephone consultation hours:
Location: Institute of Pathology
TNTB/ Study Center (2. OG; Room 302)
Schubertstraße 15
01307 Dresden
Opening hours: Monday - Thursday: 08:00 am to 10:00 am
13:30 h to 14:30 h Friday:08:00 am to 10:00 am
Outside office hours, please contact the team by e-mail.
- Determination of the tumor cell content of tumor tissue by a pathologist using HE-stained tissue sections
- Histological or immunohistological staining of tissue sections & their evaluation by a pathologist Diagnostic portfolio of the Institute of Pathology
- Digitalization of slides
- DNA/RNA isolation from fresh tissue / cryogenic tissue
- DNA/RNA isolation from FFPE tissue blocks
The most important forms at a glance
Project or study application
Service request
Storage currently takes place centrally at -80°C and in future in fully automated nitrogen storage systems and, if desired, in archives in the form of formalin-fixed tissue blocks (FFPE).
In addition to the preservation of fresh tissue, the archiving of formalin-fixed kerosene tissue (FFPE) and the delivery of tissue for research projects, the TNTB also offers the option of sample processing, the preparation of tissue sections, isolation of nucleic acids and sample examination in accordance with the institute's established routine diagnostics.