Michael Seifert, Ph.D.
© Michael Seifert
Group leader
NameMr PD Dr. rer. nat. habil. Michael Seifert
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Michael Seifert is the head of the research group Medical Bioinformatics at the Institute for Medical Informatics and Biometry. His tasks include the development of computational tools for the integrative analysis of molecular data and the provision of a bioinformatics data analysis service. Details to the specific research focus are provided on the web page of the research group.
Publications
2026
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Network-Based Prediction of Oligodendroglioma Driver Gene Candidates within the Region of the 1p/19q Co-deletion Utilizing Single-Cell Transcriptomes, 4 May 2026, In: Computational and Structural Biotechnology Journal. 35, 1, 0059Electronic (full-text) versionResearch output: Contribution to journal > Research article
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GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer, 3 Mar 2026, In: Advanced Science. 13, 13, e16578Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Development of a highly differentiated rat brain organoid model for exploring glioblastoma invasion dynamics and therapy, Mar 2026, In: Neuro-oncology. 28, 3, p. 626-642, 17 p., noaf271Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Molecular genotype-phenotype correlation in ACTB- and ACTG1-related non-muscle actinopathies, 5 Feb 2026, In: American journal of human genetics. 113, 2, p. 324-341, 18 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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A biomaterial-based platform of pancreatic cancer reveals kallikrein-related peptidase 6 (KLK6) as a mediator of neutrophil recruitment and immunosuppression, Jan 2026, In: Biomaterials. 324, 123456Electronic (full-text) versionResearch output: Contribution to journal > Research article
2025
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Patient-specific identification of genome-wide methylation and expression differences between patient-matched intra- and extracranial melanoma metastasis pairs using Hidden Markov Models, 17 Nov 2025Research output: Types of Thesis > Doctoral thesis
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Human fingertip regeneration follows clinical phases with distinct proteomic signatures, 5 Nov 2025, In: npj Regenerative Medicine. 10, 1, 51Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Comparative preclinical drug response analyses of T-prolymphocytic leukemia reveal no differences between known gene expression subgroups, 27 Oct 2025, In: Biology direct. 20, 1, 106Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Single-cell transcriptome analysis suggests cells of the tumor microenvironment as a major discriminator between brain and extracranial melanoma metastases, 16 Sep 2025, In: Biology direct. 20, 1, 97Electronic (full-text) versionResearch output: Contribution to journal > Research article
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A novel role of exostosin glycosyltransferase 2 (EXT2) in glioblastoma cell metabolism, radiosensitivity and ferroptosis, Sep 2025, In: Cell death and differentiation. 32, 9, p. 1664–1678, 15 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article