Michael Seifert, Ph.D.

Group leader

Mr PD Dr. rer. nat. habil. Michael Seifert

work Tel.
fax Fax: +49 351 458-7222

Michael Seifert is the head of the research group Medical Bioinformatics at the Institute for Medical Informatics and Biometry. His tasks include the development of computational tools for the integrative analysis of molecular data and the provision of a bioinformatics data analysis service. Details to the specific research focus are provided on the web page of the research group.

Publications

46 Entries

2023

Identification of Epigenetically Regulated Genes Distinguishing Intracranial from Extracranial Melanoma MetastasesWestphal, D., Meinhardt, M., Grützmann, K., Schöne, L., Steininger, J., Neuhaus, L. T., Wiegel, M. & 16 others, Jul 2023, In: Journal of Investigative Dermatology. 143, 7, p. 1233-1245.e17, 30 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
Plasma extracellular vesicle messenger RNA profiling identifies prognostic EV signature for non-invasive risk stratification for survival prediction of patients with pancreatic ductal adenocarcinomaHan, Y., Drobisch, P., Krüger, A., William, D., Grützmann, K., Böthig, L., Polster, H. & 16 others, 3 Feb 2023, In: Journal of hematology & oncology. 16 (2023), 1, 19 p., 7Electronic (full-text) versionResearch output: Contribution to journal > Research article
Patient-specific identification of genome-wide DNA-methylation differences between intracranial and extracranial melanoma metastasesKraft, T., Grützmann, K., Meinhardt, M., Meier, F., Westphal, D. & Seifert, M., 9 Jan 2023, In: Scientific reports. 13, 1, 444Electronic (full-text) versionResearch output: Contribution to journal > Research article
Meta-analysis of expression and the targeting of cell adhesion associated genes in nine cancer types - A one research lab re-evaluationBorodins, O., Broghammer, F., Seifert, M. & Cordes, N., Jan 2023, In: Computational and Structural Biotechnology Journal. 21, p. 2824-2836, 13 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article

2022

Computational gene expression analysis reveals distinct molecular subgroups of T-cell prolymphocytic leukemiaMikhaylenko, N., Wahnschaffe, L., Herling, M., Roeder, I. & Seifert, M., Sep 2022, In: PloS one. 17, 9, e0274463Electronic (full-text) versionResearch output: Contribution to journal > Research article
Comparative Gene Expression Analysis Reveals Similarities and Differences of Chronic Myeloid Leukemia PhasesSchwarz, A., Roeder, I. & Seifert, M., 5 Jan 2022, In: Cancers. 14, 1, 256Electronic (full-text) versionResearch output: Contribution to journal > Research article

2021

Advanced Pathogenetic Concepts in T-Cell Prolymphocytic Leukemia and Their Translational ImpactBraun, T., Dechow, A., Friedrich, G., Seifert, M., Stachelscheid, J. & Herling, M., 19 Nov 2021, In: Frontiers in oncology. 11, 775363Electronic (full-text) versionResearch output: Contribution to journal > Review article
Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial FibrillationKünzel, S. R., Hoffmann, M., Weber, S., Künzel, K., Kämmerer, S., Günscht, M., Klapproth, E. & 25 others, Oct 2021, In: Circulation research. 129, 8, p. 804-820, 17 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article

2020

The effect of the triazene compound CT913 on ovarian cancer cells in vitro and its synergistic interaction with the PARP-inhibitor olaparibWichmann, C., Klotz, D. M., Zeiler, H. J., Hilger, R. A., Grützmann, K., Krüger, A., Aust, D. & 2 others, Dec 2020, In: Gynecologic oncology. 159, 3, p. 850-859, 10 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
The clinical-phenotype continuum in DYNC1H1-related disorders—genomic profiling and proposal for a novel classificationBecker, L. L., Dafsari, H. S., Schallner, J., Abdin, D., Seifert, M., Petit, F., Smol, T. & 11 others, 1 Nov 2020, In: Journal of Human Genetics. 65, 11, p. 1003-1017, 15 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article

Links

Private research profile
Complete list of publications