Michael Seifert, Ph.D.

Group leader

Mr PD Dr. rer. nat. habil. Michael Seifert

work Tel.
fax Fax: +49 351 458-7222

Michael Seifert is the head of the research group Medical Bioinformatics at the Institute for Medical Informatics and Biometry. His tasks include the development of computational tools for the integrative analysis of molecular data and the provision of a bioinformatics data analysis service. Details to the specific research focus are provided on the web page of the research group.

Publications

46 Entries

2020

Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patientsLauber, C., Correia, N., Trumpp, A., Rieger, M. A., Dolnik, A., Bullinger, L., Roeder, I. & 1 others, 29 Jul 2020, In: Scientific reports. 10, 1, 12761Electronic (full-text) versionResearch output: Contribution to journal > Research article
Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted SequencingJohansson, P., Klein-Hitpass, L., Budeus, B., Kuhn, M., Lauber, C., Seifert, M., Roeder, I. & 6 others, 17 Apr 2020, In: Cancers. 12, 4, 986Electronic (full-text) versionResearch output: Contribution to journal > Research article

2019

Mutant IDH1 differently affects redox state and metabolism in glial cells of normal and tumor originBiedermann, J., Preussler, M., Conde, M., Peitzsch, M., Richter, S., Wiedemuth, R., Abou‐el‐ardat, K. & 13 others, Dec 2019, In: Cancers. 11, 12, 2028Electronic (full-text) versionResearch output: Contribution to journal > Research article
Targeted capture-based NGS is superior to multiplex PCR-based NGS for hereditary BRCA1 and BRCA2 gene analysis in FFPE tumor samplesZakrzewski, F., Gieldon, L., Rump, A., Seifert, M., Grützmann, K., Krüger, A., Loos, S. & 10 others, 27 Apr 2019, In: BMC cancer. 19, 1, 396Electronic (full-text) versionResearch output: Contribution to journal > Research article
Multi-omic measurements of heterogeneity in HeLa cells across laboratoriesLiu, Y., Mi, Y., Mueller, T., Kreibich, S., Williams, E. G., Van Drogen, A., Borel, C. & 16 others, 1 Mar 2019, In: Nature biotechnology. 37, 3, p. 314-322, 9 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
Discovery of highly divergent lineages of plant-associated astro-like viruses sheds light on the emergence of potyvirusesLauber, C., Bartenschlager, R., Seitz, S. & Seifert, M., 15 Jan 2019, In: Virus research. 260, p. 38-48, 11 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article

2018

Network-based analysis of oligodendrogliomas predicts novel cancer gene candidates within the region of the 1p/19q co-deletionGladitz, J., Klink, B. & Seifert, M., 11 Jun 2018, In: Acta neuropathologica communications. 6, 1, 49Electronic (full-text) versionResearch output: Contribution to journal > Research article
Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human gliomaMäder, L., Blank, A. E., Capper, D., Jansong, J., Baumgarten, P., Wirsik, N. M., Zachskorn, C. & 8 others, 8 May 2018, In: Oncotarget. 9, 35, p. 24041-24053, 13 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
Comparative analysis of histologically classified oligodendrogliomas reveals characteristic molecular differences between subgroupsLauber, C., Klink, B. & Seifert, M., 10 Apr 2018, In: BMC cancer. 18, 1, 399Electronic (full-text) versionResearch output: Contribution to journal > Research article

2017

The biology and mathematical modelling of glioma invasion: A reviewAlfonso, J. C., Talkenberger, K., Seifert, M., Klink, B., Hawkins-Daarud, A., Swanson, K. R., Hatzikirou, H. & 1 others, Nov 2017, In: Journal of the Royal Society interface. 14, 136, 20170490Electronic (full-text) versionResearch output: Contribution to journal > Review article

Links

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Complete list of publications