Publikationen
Consensus Guidance for Monitoring Individuals With Islet Autoantibody-Positive Pre-Stage 3 Type 1 Diabetes. Phillip M, Achenbach P, Addala A, Albanese-O'Neill A, Battelino T, Bell KJ, Besser REJ, Bonifacio E, Colhoun HM, Couper JJ, Craig ME, Danne T, de Beaufort C, Dovc K, Driscoll KA, Dutta S, Ebekozien O, Elding Larsson H, Feiten DJ, Frohnert BI, Gabbay RA, Gallagher MP, Greenbaum CJ, Griffin KJ, Hagopian W, Haller MJ, Hendrieckx C, Hendriks E, Holt RIG, Hughes L, Ismail HM, Jacobsen LM, Johnson SB, Kolb LE, Kordonouri O, Lange K, Lash RW, Lernmark Å, Libman I, Lundgren M, Maahs DM, Marcovecchio ML, Mathieu C, Miller KM, O'Donnell HK, Oron T, Patil SP, Pop-Busui R, Rewers MJ, Rich SS, Schatz DA, Schulman-Rosenbaum R, Simmons KM, Sims EK, Skyler JS, Smith LB, Speake C, Steck AK, Thomas NPB, Tonyushkina KN, Veijola R, Wentworth JM, Wherrett DK, Wood JR, Ziegler AG, DiMeglio LA. Diabetes Care. 2024 Jun 24:dci240042. doi: 10.2337/dci24-0042. Online ahead of print. PMID: 38912694
Consensus guidance for monitoring individuals with islet autoantibody-positive pre-stage 3 type 1 diabetes. Phillip M, Achenbach P, Addala A, Albanese-O'Neill A, Battelino T, Bell KJ, Besser REJ, Bonifacio E, Colhoun HM, Couper JJ, Craig ME, Danne T, de Beaufort C, Dovc K, Driscoll KA, Dutta S, Ebekozien O, Larsson HE, Feiten DJ, Frohnert BI, Gabbay RA, Gallagher MP, Greenbaum CJ, Griffin KJ, Hagopian W, Haller MJ, Hendrieckx C, Hendriks E, Holt RIG, Hughes L, Ismail HM, Jacobsen LM, Johnson SB, Kolb LE, Kordonouri O, Lange K, Lash RW, Lernmark Å, Libman I, Lundgren M, Maahs DM, Marcovecchio ML, Mathieu C, Miller KM, O'Donnell HK, Oron T, Patil SP, Pop-Busui R, Rewers MJ, Rich SS, Schatz DA, Schulman-Rosenbaum R, Simmons KM, Sims EK, Skyler JS, Smith LB, Speake C, Steck AK, Thomas NPB, Tonyushkina KN, Veijola R, Wentworth JM, Wherrett DK, Wood JR, Ziegler AG, DiMeglio LA. Diabetologia. 2024 Jun 24. doi: 10.1007/s00125-024-06205-5. Online ahead of print. PMID: 38910151
Infection episodes and islet autoantibodies in children at increased risk for type 1 diabetes before and during the COVID-19 pandemic. Zeller I, Weiss A, Arnolds S, Schütte-Borkovec K, Arabi S, von dem Berge T, Casteels K, Hommel A, Kordonouri O, Larsson HE, Lundgren M, Rochtus A, Snape MD, Szypowka A, Vatish M, Winkler C, Bonifacio E, Ziegler AG; GPPAD Study Group. Infection. 2024 Jun 14. doi: 10.1007/s15010-024-02312-y. Online ahead of print. PMID: 38874748
Effect of population-wide screening for presymptomatic early-stage type 1 diabetes on paediatric clinical care. Bonifacio E, Winkler C, Achenbach P, Ziegler AG. Lancet Diabetes Endocrinol. 2024 Jun;12(6):376-378. doi: 10.1016/S2213-8587(24)00101-3. Epub 2024 May 6. PMID: 38723647 No abstract available.
Caesarean section and risk of type 1 diabetes. Singh T, Weiss A, Vehik K, Krischer J, Rewers M, Toppari J, Lernmark Å, Hagopian W, Akolkar B, Bonifacio E, Ziegler AG, Winkler C; TEDDY Study Group. Diabetologia. 2024 May 31. doi: 10.1007/s00125-024-06176-7. Online ahead of print. PMID: 38819466
Früherkennung von Typ-1-Diabetes durch Inselautoantikörper-Screening – ein Positionspapier der Fr1daPlex-Projektleiter und -Schulungszentren, des BVKJ Bayern und PaedNetz Bayern e.V. Achenbach P, Berner R, Bonifacio E, Brämswig S, Braig S, Dunstheimer D, Ermer U, Ewald D, Gemulla G, Hauer J, Haupt F, Haus G, Hubmann M, Hummel S, Kandler M, Kordonouri O, Lange K, Laub O, Lorrmann A, Nellen-Hellmuth N, Sindichakis M, von dem Berge T, Warncke K, Weber L, Winkler C, Wintermeyer P, Ziegler AG. Gesundheitswesen. 2024 May 6. doi: 10.1055/a-2320-2859. Online ahead of print. PMID: 38710228 German.
Early-childhood body mass index and its association with the COVID-19 pandemic, containment measures and islet autoimmunity in children with increased risk for type 1 diabetes. Hummel S, Rosenberger S, von dem Berge T, Besser REJ, Casteels K, Hommel A, Kordonouri O, Elding Larsson H, Lundgren M, Marcus BA, Oltarzewski M, Rochtus A, Szypowska A, Todd JA, Weiss A, Winkler C, Bonifacio E, Ziegler AG; GPPAD and POInT Study Group. Diabetologia. 2024 Apr;67(4):670-678. doi: 10.1007/s00125-023-06079-z. Epub 2024 Jan 12. PMID: 38214711 Free PMC article.
Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes. Hendriks AEJ, Marcovecchio ML, Besser REJ, Bonifacio E, Casteels K, Elding Larsson H, Gemulla G, Lundgren M, Kordonouri O, Mallone R, Pociot F, Szypowska A, Toppari J, Berge TVD, Ziegler AG, Mathieu C, Achenbach P; INNODIA consortium, the Fr1da Study Group and the GPPAD Study Group. Diabetes Metab Res Rev. 2024 Feb;40(2):e3777. doi: 10.1002/dmrr.3777. PMID: 38375753
Vitamin D insufficiency in infants with increased risk of developing type 1 diabetes: a secondary analysis of the POInT Study. Jacobs A, Warnants M, Vollmuth V, Winkler C, Weiss A, Ziegler AG, Lundgren M, Elding Larsson H, Kordonouri O, von dem Berge T, Zielmann ML, Bonifacio E, Hommel A, Ołtarzewski M, Szypowska A, Besser R, Todd JA, Casteels K. BMJ Paediatr Open. 2024 Jan 12;8(1):e002212. doi: 10.1136/bmjpo-2023-002212. PMID: 38216311 Free PMC article.
Characterisation and clinical outcomes in children and adolescents with diabetes according to newly defined subgroups: a cohort study from the DPV registry. Warncke K, Eckert A, Bonifacio E, Achenbach P, Kordonouri O, Meissner T, Ohlenschläger U, Bonfig W, Ziegler AG, Holl RW. EClinicalMedicine. 2023 Sep 8;64:102208. doi: 10.1016/j.eclinm.2023.102208. eCollection 2023 Oct. PMID: 37731934 Free PMC article.
SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood. Lugar M, Eugster A, Achenbach P, von dem Berge T, Berner R, Besser REJ, Casteels K, Elding Larsson H, Gemulla G, Kordonouri O, Lindner A, Lundgren M, Müller D, Oltarzewski M, Rochtus A, Scholz M, Szypowska A, Todd JA, Ziegler AG, Bonifacio E; GPPAD Study Group. JAMA. 2023 Sep 26;330(12):1151-1160. doi: 10.1001/jama.2023.16348. PMID: 37682551 Free PMC article.
Children diagnosed with presymptomatic type 1 diabetes through public health screening have milder diabetes at clinical manifestation. Hummel S, Carl J, Friedl N, Winkler C, Kick K, Stock J, Reinmüller F, Ramminger C, Schmidt J, Lwowsky D, Braig S, Dunstheimer D, Ermer U, Gerstl EM, Weber L, Nellen-Hellmuth N, Brämswig S, Sindichakis M, Tretter S, Lorrmann A, Bonifacio E, Ziegler AG, Achenbach P; Fr1da Study Group. Diabetologia. 2023 Sep;66(9):1633-1642. doi: 10.1007/s00125-023-05953-0. Epub 2023 Jun 17. PMID: 37329450 Free PMC article.
Type 1 Diabetes Incidence and Risk in Children With a Diagnosis of COVID-19. Weiss A, Donnachie E, Beyerlein A, Ziegler AG, Bonifacio E. JAMA. 2023 Jun 20;329(23):2089-2091. doi: 10.1001/jama.2023.8674. PMID: 37213115 Free PMC article.
Potential of TCR sequencing in graft-versus-host disease. Goel M, Eugster A, Schetelig J, Bonifacio E, Bornhäuser M, Link-Rachner CS. Bone Marrow Transplant. 2023 Mar;58(3):239-246. doi: 10.1038/s41409-022-01885-2. Epub 2022 Dec 7. PMID: 36477111 Free PMC article. Review.
Next Generation Biobanking: Employing a Robotic System for Automated Mononuclear Cell Isolation. Fuchs YF, Brunner J, Weigelt M, Schieferdecker A, Morgenstern R, Sturm A, Winter B, Jambor H, Stölzel F, Ruhnke L, von Bonin M, Rücker-Braun E, Heidenreich F, Fuchs A, Bonifacio E, Bornhäuser M, Poitz DM, Altmann H. Biopreserv Biobank. 2023 Feb;21(1):106-110. doi: 10.1089/bio.2021.0181. Epub 2022 Oct 13. PMID: 36251308 Free PMC article. No abstract available.
Successful integration of newborn genetic testing into UK routine screening using prospective consent to determine eligibility for clinical trials. Bendor-Samuel OM, Wishlade T, Willis L, Aley P, Choi E, Craik R, Mujadidi Y, Mounce G, Roseman F, De La Horra Gozalo A, Bland J, Taj N, Smith I, Ziegler AG, Bonifacio E, Winkler C, Haupt F, Todd JA, Servais L, Snape MD, Vatish M; GPPAD Study Group. Arch Dis Child. 2023 Jan;108(1):26-30. doi: 10.1136/archdischild-2022-324270. Epub 2022 Sep 28. PMID: 36171064 Free PMC article.
Correction to: Progression likelihood score identifies substages of presymptomatic type 1 diabetes in childhood public health screening. Weiss A, Zapardiel-Gonzalo J, Voss F, Jolink M, Stock J, Haupt F, Kick K, Welzhofer T, Heublein A, Winkler C, Achenbach P, Ziegler AG, Bonifacio E; Fr1da-study group. Diabetologia. 2022 Dec;65(12):2175. doi: 10.1007/s00125-022-05798-z. PMID: 36194252 Free PMC article. No abstract available.
Progression likelihood score identifies substages of presymptomatic type 1 diabetes in childhood public health screening. Weiss A, Zapardiel-Gonzalo J, Voss F, Jolink M, Stock J, Haupt F, Kick K, Welzhofer T, Heublein A, Winkler C, Achenbach P, Ziegler AG, Bonifacio E; Fr1da-study group. Diabetologia. 2022 Dec;65(12):2121-2131. doi: 10.1007/s00125-022-05780-9. Epub 2022 Aug 27. PMID: 36028774 Free PMC article.
Corrigendum: A novel type I interferon primed dendritic cell subpopulation in TREX1 mutant chilblain lupus patients. Eugster A, Müller D, Gompf A, Reinhardt S, Lindner A, Ashton M, Zimmermann N, Beissert S, Bonifacio E, Günther C. Front Immunol. 2022 Nov 25;13:1094578. doi: 10.3389/fimmu.2022.1094578. eCollection 2022. PMID: 36518762 Free PMC article.
Elevations in blood glucose before and after the appearance of islet autoantibodies in children. Warncke K, Weiss A, Achenbach P, von dem Berge T, Berner R, Casteels K, Groele L, Hatzikotoulas K, Hommel A, Kordonouri O, Elding Larsson H, Lundgren M, Marcus BA, Snape MD, Szypowska A, Todd JA, Bonifacio E, Ziegler AG; GPPAD and POInT Study Groups. J Clin Invest. 2022 Oct 17;132(20):e162123. doi: 10.1172/JCI162123. PMID: 36250461 Free PMC article.
SARS-CoV-2 Infections and Presymptomatic Type 1 Diabetes Autoimmunity in Children and Adolescents From Colorado, USA, and Bavaria, Germany. Rewers M, Bonifacio E, Ewald D, Geno Rasmussen C, Jia X, Pyle L, Ziegler AG; ASK Study Group and Fr1da Study Group. JAMA. 2022 Sep 27;328(12):1252-1255. doi: 10.1001/jama.2022.14092. PMID: 35930271 Free PMC article.
Autoantibodies against ATP4A are a feature of the abundant autoimmunity that develops in first-degree relatives of patients with type 1 diabetes. Zielmann ML, Jolink M, Winkler C, Eugster A, Müller D, Scholz M, Ziegler AG, Bonifacio E. Pediatr Diabetes. 2022 Sep;23(6):714-720. doi: 10.1111/pedi.13361. Epub 2022 May 22. PMID: 35561070
A classification and regression tree analysis identifies subgroups of childhood type 1 diabetes. Achenbach P, Hippich M, Zapardiel-Gonzalo J, Karges B, Holl RW, Petrera A, Bonifacio E, Ziegler AG; DiMelli Study group and DPV Study group. EBioMedicine. 2022 Aug;82:104118. doi: 10.1016/j.ebiom.2022.104118. Epub 2022 Jul 5. PMID: 35803018 Free PMC article.
A Novel Type I Interferon Primed Dendritic Cell Subpopulation in TREX1 Mutant Chilblain Lupus Patients. Eugster A, Müller D, Gompf A, Reinhardt S, Lindner A, Ashton M, Zimmermann N, Beissert S, Bonifacio E, Günther C. Front Immunol. 2022 Jul 13;13:897500. doi: 10.3389/fimmu.2022.897500. eCollection 2022. PMID: 35911727 Free PMC article.
Distinguishing activated T regulatory cell and T conventional cells by single-cell technologies. Reinhardt J, Sharma V, Stavridou A, Lindner A, Reinhardt S, Petzold A, Lesche M, Rost F, Bonifacio E, Eugster A. Immunology. 2022 May;166(1):121-137. doi: 10.1111/imm.13460. Epub 2022 Mar 2. PMID: 35196398 Free PMC article.
Reproducibility of 10x Genomics single cell RNA sequencing method in the immune cell environment. Kraus G, Weigelt M, Reinhardt S, Petzold A, Dahl A, Bonifacio E. J Immunol Methods. 2022 Mar;502:113227. doi: 10.1016/j.jim.2022.113227. Epub 2022 Jan 12. PMID: 35031279
Holthaus L, Sharma V, Brandt D, Ziegler AG, Jastroch M, Bonifacio E. Functional and metabolic fitness of human CD4+ T lymphocytes during metabolic stress. Life Sci Alliance. 2021 Sep 27;4(12):e202101013. doi: 10.26508/lsa.202101013. Print 2021 Dec. PMID: 34580176
Brænne I, Onengut-Gumuscu S, Chen R, Manichaikul AW, Rich SS, Chen WM, Farber CR; TEDDY Study Group. Dynamic changes in immune gene co-expression networks predict development of type 1 diabetes. Sci Rep. 2021 Nov 22;11(1):22651. doi: 10.1038/s41598-021-01840-z. PMID: 34811390
Ziegler AG, Arnolds S, Kölln A, Achenbach P, Berner R, Bonifacio E, Casteels K, Elding Larsson H, Gündert M, Hasford J, Kordonouri O, Lundgren M, Oltarzewski M, Pekalski ML, Pfirrmann M, Snape MD, Szypowska A, Todd JA; GPPAD STUDY GROUP. Supplementation with Bifidobacterium longum subspecies infantis EVC001 for mitigation of type 1 diabetes autoimmunity: the GPPAD-SINT1A randomised controlled trial protocol. BMJ Open. 2021 Nov 9;11(11):e052449. doi: 10.1136/bmjopen-2021-052449. PMID: 34753762
Krämer B, Knoll R, Bonaguro L, ToVinh M, Raabe J, Astaburuaga-García R, Schulte-Schrepping J, Kaiser KM, Rieke GJ, Bischoff J, Monin MB, Hoffmeister C, Schlabe S, De Domenico E, Reusch N, Händler K, Reynolds G, Blüthgen N, Hack G, Finnemann C, Nischalke HD, Strassburg CP, Stephenson E, Su Y, Gardner L, Yuan D, Chen D, Goldman J, Rosenstiel P, Schmidt SV, Latz E, Hrusovsky K, Ball AJ, Johnson JM, Koenig PA, Schmidt FI, Haniffa M, Heath JR, Kümmerer BM, Keitel V, Jensen B, Stubbemann P, Kurth F, Sander LE, Sawitzki B; Deutsche COVID-19 OMICS Initiative (DeCOI), Aschenbrenner AC, Schultze JL, Nattermann J. Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19. Immunity. 2021 Nov 9;54(11):2650-2669.e14. doi: 10.1016/j.immuni.2021.09.002. Epub 2021 Sep 4. PMID: 34592166
von Herrath M, Bonifacio E. How benign autoimmunity becomes detrimental in type 1 diabetes. Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2116508118. doi: 10.1073/pnas.2116508118. PMID: 34697240
Watts D, Janßen M, Jaykar M, Palmucci F, Weigelt M, Petzold C, Hommel A, Sparwasser T, Bonifacio E, Kretschmer K. Transient Depletion of Foxp3+ Regulatory T Cells Selectively Promotes Aggressive β Cell Autoimmunity in Genetically Susceptible DEREG Mice. Front Immunol. 2021 Aug 10;12:720133. doi: 10.3389/fimmu.2021.720133. eCollection 2021. PMID: 34447385
Schetelig J, Heidenreich F, Baldauf H, Trost S, Falk B, Hoßbach C, Real R, Roers A, Lindemann D, Dalpke A, Kolditz M, de With K, Bornhäuser M, Bonifacio EE, Rücker-Braun E, Lange V, Markert J, Barth R, Hofmann JA, Sauter J, Bernas SN, Schmidt AH. Individual HLA-A, -B, -C, and -DRB1 Genotypes Are No Major Factors Which Determine COVID-19 Severity. Front Immunol. 2021 Jul 26;12:698193. doi: 10.3389/fimmu.2021.698193. eCollection 2021. PMID: 34381451
Wigger L, Barovic M, Brunner AD, Marzetta F, Schöniger E, Mehl F, Kipke N, Friedland D, Burdet F, Kessler C, Lesche M, Thorens B, Bonifacio E, Legido-Quigley C, Barbier Saint Hilaire P, Delerive P, Dahl A, Klose C, Gerl MJ, Simons K, Aust D, Weitz J, Distler M, Schulte AM, Mann M, Ibberson M, Solimena M. Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes. Nat Metab. 2021 Jul;3(7):1017-1031. doi: 10.1038/s42255-021-00420-9. Epub 2021 Jun 28. PMID: 34183850
Hummel S, Weiß A, Bonifacio E, Agardh D, Akolkar B, Aronsson CA, Hagopian WA, Koletzko S, Krischer JP, Lernmark Å, Lynch K, Norris JM, Rewers MJ, She JX, Toppari J, Uusitalo U, Vehik K, Virtanen SM, Beyerlein A, Ziegler AG; TEDDY Study Group. Associations of breastfeeding with childhood autoimmunity, allergies, and overweight: The Environmental Determinants of Diabetes in the Young (TEDDY) study. Am J Clin Nutr. 2021 Jul 1;114(1):134-142. doi: 10.1093/ajcn/nqab065. PMID: 33831944
Warnat-Herresthal S, Schultze H, Shastry KL, Manamohan S, Mukherjee S, Garg V, Sarveswara R, Händler K, Pickkers P, Aziz NA, Ktena S, Tran F, Bitzer M, Ossowski S, Casadei N, Herr C, Petersheim D, Behrends U, Kern F, Fehlmann T, Schommers P, Lehmann C, Augustin M, Rybniker J, Altmüller J, Mishra N, Bernardes JP, Krämer B, Bonaguro L, Schulte-Schrepping J, De Domenico E, Siever C, Kraut M, Desai M, Monnet B, Saridaki M, Siegel CM, Drews A, Nuesch-Germano M, Theis H, Heyckendorf J, Schreiber S, Kim-Hellmuth S; COVID-19 Aachen Study (COVAS), Nattermann J, Skowasch D, Kurth I, Keller A, Bals R, Nürnberg P, Rieß O, Rosenstiel P, Netea MG, Theis F, Mukherjee S, Backes M, Aschenbrenner AC, Ulas T; Deutsche COVID-19 Omics Initiative (DeCOI), Breteler MMB, Giamarellos-Bourboulis EJ, Kox M, Becker M, Cheran S, Woodacre MS, Goh EL, Schultze JL. Swarm Learning for decentralized and confidential clinical machine learning. Nature. 2021 Jun;594(7862):265-270. doi: 10.1038/s41586-021-03583-3. Epub 2021 May 26. PMID: 34040261
Hippich M, Sifft P, Zapardiel-Gonzalo J, Böhmer MM, Lampasona V, Bonifacio E, Ziegler AG. A public health antibody screening indicates a marked increase of SARS-CoV-2 exposure rate in children during the second wave. Med (N Y). 2021 May 14;2(5):571-572. doi: 10.1016/j.medj.2021.03.019. Epub 2021 Apr 3. PMID: 33842906
Assfalg R, Knoop J, Hoffman KL, Pfirrmann M, Zapardiel-Gonzalo JM, Hofelich A, Eugster A, Weigelt M, Matzke C, Reinhardt J, Fuchs Y, Bunk M, Weiss A, Hippich M, Halfter K, Hauck SM, Hasford J, Petrosino JF, Achenbach P, Bonifacio E, Ziegler AG. Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial. Diabetologia. 2021 May;64(5):1079-1092. doi: 10.1007/s00125-020-05376-1. Epub 2021 Jan 30. PMID: 33515070
Xhonneux LP, Knight O, Lernmark Å, Bonifacio E, Hagopian WA, Rewers MJ, She JX, Toppari J, Parikh H, Smith KGC, Ziegler AG, Akolkar B, Krischer JP, McKinney EF. Transcriptional networks in at-risk individuals identify signatures of type 1 diabetes progression. Sci Transl Med. 2021 Mar 31;13(587):eabd5666. doi: 10.1126/scitranslmed.abd5666. PMID: 33790023
Bonifacio E, Weiß A, Winkler C, Hippich M, Rewers MJ, Toppari J, Lernmark Å, She JX, Hagopian WA, Krischer JP, Vehik K, Schatz DA, Akolkar B, Ziegler AG; TEDDY Study Group. An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood. Diabetes Care. 2021 Feb 24:dc202122. doi: 10.2337/dc20-2122. Online ahead of print. PMID: 33627366
Hippich M, Holthaus L, Assfalg R, Zapardiel-Gonzalo J, Kapfelsperger H, Heigermoser M, Haupt F, Ewald DA, Welzhofer TC, Marcus BA, Heck S, Koelln A, Stock J, Voss F, Secchi M, Piemonti L, de la Rosa K, Protzer U, Boehmer M, Achenbach P, Lampasona V, Bonifacio E, Ziegler AG. A Public Health Antibody Screening Indicates a 6-Fold Higher SARS-CoV-2 Exposure Rate than Reported Cases in Children. Med (N Y). 2021 Feb 12;2(2):149-163.e4. doi: 10.1016/j.medj.2020.10.003. Epub 2020 Oct 29. PMID: 33163984
Ziegler AG, Bonifacio E. Shortening the paths to type 1 diabetes mellitus prevention. Nat Rev Endocrinol. 2021 Feb;17(2):73-74. doi: 10.1038/s41574-020-00450-5. PMID: 33257822
Aschenbrenner AC, Mouktaroudi M, Krämer B, Oestreich M, Antonakos N, Nuesch-Germano M, Gkizeli K, Bonaguro L, Reusch N, Baßler K, Saridaki M, Knoll R, Pecht T, Kapellos TS, Doulou S, Kröger C, Herbert M, Holsten L, Horne A, Gemünd ID, Rovina N, Agrawal S, Dahm K, van Uelft M, Drews A, Lenkeit L, Bruse N, Gerretsen J, Gierlich J, Becker M, Händler K, Kraut M, Theis H, Mengiste S, De Domenico E, Schulte-Schrepping J, Seep L, Raabe J, Hoffmeister C, ToVinh M, Keitel V, Rieke G, Talevi V, Skowasch D, Aziz NA, Pickkers P, van de Veerdonk FL, Netea MG, Schultze JL, Kox M, Breteler MMB, Nattermann J, Koutsoukou A, Giamarellos-Bourboulis EJ, Ulas T; German COVID-19 Omics Initiative (DeCOI). Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients. Genome Med. 2021 Jan 13;13(1):7. doi: 10.1186/s13073-020-00823-5. PMID: 33441124
Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Franzenburg J, Geisen U, Josephs-Spaulding J, Köhler P, Künstner A, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Brandt B, Bruse N, Dörr J, Dräger A, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Franzenburg S, Frey N, Friedrichs A, Fuß J, Glück A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Junker R, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lier C, Lindner M, Marinos G, Markewitz R, Nattermann J, Noth R, Pickkers P, Rabe KF, Renz A, Röcken C, Rupp J, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wandinger KP, Wittig M, Zimmermann J, Busch H, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P; HCA Lung Biological Network; Deutsche COVID-19 Omics Initiative (DeCOI). Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19. Immunity. 2020 Dec 15;53(6):1296-1314.e9. doi: 10.1016/j.immuni.2020.11.017. Epub 2020 Nov 26. PMID: 33296687
Hollstein T, Schulte DM, Schulz J, Glück A, Ziegler AG, Bonifacio E, Wendorff M, Franke A, Schreiber S, Bornstein SR, Laudes M. Autoantibody-negative insulin-dependent diabetes mellitus after SARS-CoV-2 infection: a case report. Nat Metab. 2020 Oct;2(10):1021-1024. doi: 10.1038/s42255-020-00281-8. Epub 2020 Sep 2. PMID: 32879473
Schulte-Schrepping J, Reusch N, Paclik D, Baßler K, Schlickeiser S, Zhang B, Krämer B, Krammer T, Brumhard S, Bonaguro L, De Domenico E, Wendisch D, Grasshoff M, Kapellos TS, Beckstette M, Pecht T, Saglam A, Dietrich O, Mei HE, Schulz AR, Conrad C, Kunkel D, Vafadarnejad E, Xu CJ, Horne A, Herbert M, Drews A, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, Müller-Redetzky H, Heim KM, Machleidt F, Uhrig A, Bosquillon de Jarcy L, Jürgens L, Stegemann M, Glösenkamp CR, Volk HD, Goffinet C, Landthaler M, Wyler E, Georg P, Schneider M, Dang-Heine C, Neuwinger N, Kappert K, Tauber R, Corman V, Raabe J, Kaiser KM, Vinh MT, Rieke G, Meisel C, Ulas T, Becker M, Geffers R, Witzenrath M, Drosten C, Suttorp N, von Kalle C, Kurth F, Händler K, Schultze JL, Aschenbrenner AC, Li Y, Nattermann J, Sawitzki B, Saliba AE, Sander LE; Deutsche COVID-19 OMICS Initiative (DeCOI). Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment. Cell. 2020 Sep 17;182(6):1419-1440.e23. doi: 10.1016/j.cell.2020.08.001. Epub 2020 Aug 5. PMID: 32810438
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