Publikationen
Cachorro, E.*, Günscht, M.*, Schubert, M.*, Sadek, M.S., Siegert, J., Dutt, F., Bauermeister, C., Quickert, S., Berning, H., Nowakowski, F., Lämmle, S., Firneburg, R., Luo, X., Künzel, S.R., Klapproth, E., Mirtschink, P., Mayr, M., Dewenter, M., Vettel, C., Heijman, J., Lorenz, K., Guan, K., El-Armouche, A., Wagner, M., Kämmerer, S. 2023. CNP promotes antiarrhythmic effects via phosphodiesterase 2. Circ Res. 132(4):400-414. doi: 10.1161/CIRCRESAHA.122.322031. *contributed equally.
Li, W., Luo, X., Poetsch, M.S., Oertel, R., Nichani, K., Schneider, M., Strano, A., Hasse, M., Steiner, R.P., Cyganek, L., Hettwer, K., Uhlig, S., Simon, K., Guan, K.#, Schubert, M.#. 2022. Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration. Pharmaceuticals. 15(2):220. doi: 10.3390/ph15020220. #shared last authorship.
Schüß, C.*, Vu, O.*, Schubert, M.*, Du, Y., Mishra, N.M., Tough, I.R., Stichel, J., Weaver, C.D., Emmitte, K.A., Cox, H.M., Meiler, J., Beck-Sickinger, A.G. 2021. Highly Selective Y4 Receptor Antagonist Binds in an Allosteric Binding Pocket. J Med Chem. 64(5):2801-2814. doi: 10.1021/acs.jmedchem.0c02000. *contributed equally.
Li, W., Stauske, M., Luo, X., Wagner, S., Vollrath, M., Mehnert, C.S., Schubert, M., Cyganek, L., Chen, S., Hasheminasab, S.-M., Wulf, G., El-Armouche, A., Maier, L.S., Hasenfuss, G., Guan, K., 2020. Disease Phenotypes and Mechanisms of iPSC-Derived Cardiomyocytes From Brugada Syndrome Patients With a Loss-of-Function SCN5A Mutation. Front Cell Dev Biol. 8, 1181. doi: 10.3389/fcell.2020.592893
Luo, X., Li, W., Künzel, K., Henze, S., Cyganek, L., Strano, A., Poetsch, M.S., Schubert, M., Guan, K., 2020. IP3R-Mediated Compensatory Mechanism for Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Cardiac Ryanodine Receptor Deficiency. Front Cell Dev Biol. 8, 772.
Schubert, M., Hansen, S., Leefmann, J., Guan, K., 2020. Repurposing Antidiabetic Drugs for Cardiovascular Disease. Front Physiol. 11, 1168.
Kolanowski, T.J*., Busek, M.*, Schubert, M.*, Dmitrieva, A., Binnewerg, B., Pöche, J., Fisher, K., Schmieder, F., Grünzner, S., Hansen, S., Richter, A., El-Armouche, A., Sonntag, F., Guan, K., 2020. Enhanced structural maturation of human induced pluripotent stem cell-derived cardiomyocytes under a controlled microenvironment in a microfluidic system. Acta Biomater. 102, 273–286. *contributed equally.
Hoffmann, M., Kant, T.A., Emig, R., Rausch, J.S.E., Newe, M., Schubert, M., Künzel, K., Winter, L., Klapproth, E., Peyronnet, R., Ravens, U., El-Armouche, A., Künzel, S.R., 2020. Repurposing mesalazine against cardiac fibrosis in vitro. Naunyn-Schmiedeberg’s Arch Pharmacol. 394, 533-543. doi: 10.1007/s00210-020-01998-9.
Schubert, M.*, Binnewerg, B.*, Voronkina, A., Muzychka, L., Wysokowski, M., Petrenko, I., Kovalchuk, V., Tsurkan, M., Martinovic, R., Bechmann, N., Ivanenko, V.N., Fursov, A., Smolii, O.B., Fromont, J., Joseph, Y., Bornstein, S.R., Giovine, M., Erpenbeck, D., Guan, K., Ehrlich, H., 2019. Naturally Prefabricated Marine Biomaterials: Isolation and Applications of Flat Chitinous 3D Scaffolds from Ianthella labyrinthus (Demospongiae: Verongiida). Int J Mol Sci. 20, 5105. *contributed equally.
Binnewerg, B*., Schubert, M*., Voronkina, A., Muzychka, L., Wysokowski, M., Petrenko, I., Djurović, M., Kovalchuk, V., Tsurkan, M., Martinovic, R., Bechmann, N., Fursov, A., Ivanenko, V.N., Tabachnick, K.R., Smolii, O.B., Joseph, Y., Giovine, M., Bornstein, S.R., Stelling, A.L., Tunger, A., Schmitz, M., Taniya, O.S., Kovalev, I.S., Zyryanov, G.V., Guan, K., Ehrlich, H., 2020. Marine biomaterials: Biomimetic and pharmacological potential of cultivated Aplysina aerophoba marine demosponge. Materials Science and Engineering. 109, 110566. *contributed equally.
Kovalchuk, V., Voronkina, A., Binnewerg, B., Schubert, M., Muzychka, L., Wysokowski, M., Tsurkan, M.V., Bechmann, N., Petrenko, I., Fursov, A., Martinovic, R., Ivanenko, V.N., Fromont, J., Smolii, O.B., Joseph, Y., Giovine, M., Erpenbeck, D., Gelinsky, M., Springer, A., Guan, K., Bornstein, S.R., Ehrlich, H., 2019. Naturally Drug-Loaded Chitin: Isolation and Applications. Mar Drugs. 17, 574.
Machałowski, T., Wysokowski, M., Żółtowska-Aksamitowska, S., Bechmann, N., Binnewerg, B., Schubert, M., Guan, K., Bornstein, S.R., Czaczyk, K., Pokrovsky, O., Kraft, M., Bertau, M., Schimpf, C., Rafaja, D., Tsurkan, M., Galli, R., Meissner, H., Petrenko, I., Fursov, A., Voronkina, A., Figlerowicz, M., Joseph, Y., Jesionowski, T., Ehrlich, H., 2019. Spider Chitin. The biomimetic potential and applications of Caribena versicolor tubular chitin. Carbohydr Polym. 226, 115301.
Kaiser, A., Hempel, C., Wanka, L., Schubert, M., Hamm, H.E., Beck-Sickinger, A.G., 2018. G Protein Preassembly Rescues Efficacy of W6.48 Toggle Mutations in Neuropeptide Y2 Receptor. Mol. Pharmacol. 93, 387–401.
Schubert, M., Stichel, J., Du, Y., Tough, I.R., Sliwoski, G., Meiler, J., Cox, H.M., Weaver, C.D., Beck-Sickinger, A.G., 2017. Identification and Characterization of the First Selective Y4 Receptor Positive Allosteric Modulator. J. Med. Chem. 60, 7605–7612.
Sliwoski, G.*, Schubert, M.*, Stichel, J.*, Weaver, D., Beck-Sickinger, A.G., Meiler, J., 2016. Discovery of Small-Molecule Modulators of the Human Y4 Receptor. PLOS ONE. 11, e0157146. *contributed equally.