Tomislav Volosen

KoSyn- cell-based communication between yeast and bacteria

This interdisciplinary project is a collaboration of different research groups of the TU Dresden. The project idea is using bacteria and yeast in controlled conditions to implement complex (bio)technical processes. In the project, yeasts and bacteria are genetically modified in such a way that they can communicate and react with each other via specific signal peptides. This controlled communication of the microorganisms is demonstrated within the KoSyn project by the detection and enzymatic degradation of an antibiotic. The bacteria act as sensors that detect the presence of the antibiotic and pass this information on to the yeasts, which then produce and secrete the enzymes required to degrade the antibiotic.

Keywords: Bacillus subtilis, genetic engineering, Saccharomyces cerevisiae, Schizosaccharomyces pombe, cell-signaling

More information can be found here.

Since 2020
PhD Student, General Microbiology, Institute of Microbiology, TU Dresden, Germany

2019
Master thesis in the group of Ákos T. Kovács, Technical University of Denmark (DTU), Copenhagen, Denmark

2017– 2019
Graduate Study of Bioprocess Engineering, Faculty of Food Technology and Biotechnology, University of Zagreb, Croatia

2014– 2017
Undergraduate Study of Biotechnology, Faculty of Food Technology and Biotechnology, University of Zagreb, Croatia

in progress...