Jan 28, 2026
DcGC Hosts Workshop on Spatial Transcriptomics Data Analysis
A group photo of participants of the hands-on training with the DcGC team (first row).
In January 2026, the DRESDEN-concept Genome Center (DcGC) partnered with 10x Genomics to host a workshop on spatial transcriptomics data analysis, with a focus on the imaging-based Xenium platform. Xenium enables high-resolution mapping of transcription directly in tissue sections, with subcellular resolution and single-molecule sensitivity.
Following the Summer School on spatial transcriptomics in May 2025, the DcGC observed strong demand across the Dresden research campus for dedicated training in single-cell and spatial transcriptomics data analysis. As spatial omics continues to evolve rapidly, with new technologies and analysis tools emerging at pace, the DcGC remains committed to providing the Dresden research community with access to state-of-the-art methods. Through tailored workshops and hands-on training, the facility aims to help researchers make the best use of these approaches in their own projects.
To meet the growing interest in the imaging-based Xenium platform, the DcGC designed a new workshop in two parts: an introductory seminar on the technology, followed by a practical, hands-on training in data analysis.
The workshop began with a seminar on the Xenium platform led by 10x Genomics, bringing together around 60 attendees from the Dresden research campus. Four speakers presented the latest developments and key considerations for generating high-quality datasets. The experts shared practical recommendations for sample preparation and introduced participants to Xenium data in practice, including first steps in data exploration using the Xenium Explorer software.
Afterwards, the workshop transitioned into a hands-on training led by the DcGC bioinformatics team, with 18 registered participants from multiple institutes at TU Dresden, UKD, and MPI-CBG. Participants learned how to import Xenium data into RStudio and Seurat, perform quality control and preprocessing, identify spatial clusters, and annotate cell types and tissue regions. The sessions were highly interactive, with lively discussion, excellent questions, and collaborative troubleshooting throughout.
The organizers thank 10x Genomics, the speakers, and all participants for making this workshop a great success!