Prof. Ingo Roeder, Ph.D.
© P.Benjamin/NCTDD
Chair for Medical Biometry and Statistics
NameMr Prof. Dr. rer. med. Ingo Röder
Institute Director
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Prof. Ingo Roeder is Head of the Institute for Medical Informatics and Biometry. He is a member of the Carl Gustav Carus Medical Faculty at the Technische Universität Dresden. In particular, he holds the Chair for Medical Statistics and Biometry. Since 2015 Prof. Roeder has been scientific head of the Core Unit for Data Management and Analytics (DMA) at the National Centre for Tumor Diseases (NCT) at the partner site Dresden. Between 2014 and 2018 he acted as CIO of the TU Dresden School of Medicine. Since 2018 he ihas been dean of studies at the Faculty of Medicine.
Prof. Roeder’s research focus covers the following areas:
Theoretical Biology/System medicine:
- Application of mathematical models in the context of treatment optimisation/model-based experimental/study design (e.g. regarding CML, AML, T-PLL)
- Dynamics of molecular regulation networks
- Theoretical concepts of stem cell organisation (theoretical setm cell biology)
- Clonal competition phenomena and stem cell/niche interactions
Biostatistics/Bioinformatics:
- Statistical modelling (e.g. mixed-effect models)
- Analysis of cellular genealogies
- Analysis of single cell tracking data
- Model-based trial design
- Integrative analysis of molecular data (e.g. NGS-based)
Medical Informatics:
- Data integration models
- „Big Data“ in oncology
- Integration of model predictions in processes of clinical decision-making
Publications
2007
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Leukaemia stem cells: Hit or miss? [1], 26 Feb 2007, In: British journal of cancer. 96, 4, p. 677-678, 2 p.Electronic (full-text) versionResearch output: Contribution to journal > Letter
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Stem cell fate analysis revisited: interpretation of individual clone dynamics in the light of a new paradigm of stem cell organization, 2007, In: BioMed Research International. 3, 1, 84656Electronic (full-text) versionResearch output: Contribution to journal > Review article
2006
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Discrete stem cells: subsets or a continuum?, 1 Dec 2006, In: Blood. 108, 12, p. 3949Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications, Oct 2006, In: Nature medicine. 12, 10, p. 1181-4, 4 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Towards an understanding of lineage specification in hematopoietic stem cells: a mathematical model for the interaction of transcription factors GATA-1 and PU.1, 21 Aug 2006, In: Journal of theoretical biology. 241, 4, p. 852-65, 14 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Quantitative stem cell biology: computational studies in the hematopoietic system, Jul 2006, In: Current Opinion in Hematology. 13, 4, p. 222-228, 7 p.Electronic (full-text) versionResearch output: Contribution to journal > Review article
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Asymmetry of stem cell fate and the potential impact of the niche: observations, simulations, and interpretations, 2006, In: Stem cell reviews. 2, 3, p. 171–180, 10 p.Electronic (full-text) versionResearch output: Contribution to journal > Review article
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Systems stem cell biology, 2006, BIOMAT 2006 – International Symposium on Mathematical and Computational Biology. World Scientific Publishing CompanyElectronic (full-text) versionResearch output: Contribution to book/conference proceedings/anthology/report > Chapter in book/Anthology/Report
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Theoretical Concepts of Tissue Stem-Cell Organization, 2006, Tissue Stem Cells. CRC Press - Taylor & Francis Group, 20 p.Electronic (full-text) versionResearch output: Contribution to book/conference proceedings/anthology/report > Chapter in book/Anthology/Report
2005
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In vitro, clinical, and microbiological evaluation of a linear oscillating device for scaling and root planing, Nov 2005, In: Journal of periodontology. 76, 11, p. 1942-1949, 8 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article