Prof. Ingo Roeder, Ph.D.
© P.Benjamin/NCTDD
Chair for Medical Biometry and Statistics
NameMr Prof. Dr. rer. med. Ingo Röder
Institute Director
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Prof. Ingo Roeder is Head of the Institute for Medical Informatics and Biometry. He is a member of the Carl Gustav Carus Medical Faculty at the Technische Universität Dresden. In particular, he holds the Chair for Medical Statistics and Biometry. Since 2015 Prof. Roeder has been scientific head of the Core Unit for Data Management and Analytics (DMA) at the National Centre for Tumor Diseases (NCT) at the partner site Dresden. Between 2014 and 2018 he acted as CIO of the TU Dresden School of Medicine. Since 2018 he ihas been dean of studies at the Faculty of Medicine.
Prof. Roeder’s research focus covers the following areas:
Theoretical Biology/System medicine:
- Application of mathematical models in the context of treatment optimisation/model-based experimental/study design (e.g. regarding CML, AML, T-PLL)
- Dynamics of molecular regulation networks
- Theoretical concepts of stem cell organisation (theoretical setm cell biology)
- Clonal competition phenomena and stem cell/niche interactions
Biostatistics/Bioinformatics:
- Statistical modelling (e.g. mixed-effect models)
- Analysis of cellular genealogies
- Analysis of single cell tracking data
- Model-based trial design
- Integrative analysis of molecular data (e.g. NGS-based)
Medical Informatics:
- Data integration models
- „Big Data“ in oncology
- Integration of model predictions in processes of clinical decision-making
Publications
2005
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Increased power of microarray analysis by use of an algorithm based on a multivariate procedure, 1 Sep 2005, In: Bioinformatics. 21, 17, p. 3530-3534, 5 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Competitive clonal hematopoiesis in mouse chimeras explained by a stochastic model of stem cell organization, 15 Jan 2005, In: Blood. 105, 2, p. 609–616, 8 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
2004
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Conceptual models to understand tissue stem cell organization, Mar 2004, In: Current Opinion in Hematology. 11, 2, p. 81-87, 7 p.Electronic (full-text) versionResearch output: Contribution to journal > Review article
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Micro array based gene expression analysis using parametric multivariate tests per gene a generalized application of multiple procedures with data-driven order of hypotheses, 2004, In: Biometrical Journal. 46, 6, p. 687-698Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Simulation of Haematopoietic Stem Cell Organisation Using a Single Cell Based Model Approach, 2004, Function and Regulation of Cellular systems. Birkhauser Verlag Basel, p. 287-293Electronic (full-text) versionResearch output: Contribution to book/conference proceedings/anthology/report > Chapter in book/Anthology/Report
2003
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Quantitative tissue stem cell modeling, 1 Aug 2003, In: Blood. 102, 3, p. 1143-1144Electronic (full-text) versionResearch output: Contribution to journal > Letter
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Dynamical Modeling of Hematopoietic Stem Cell Organization - Design and Validation of the New Concept of Within-Tissue Plasticity, 2003Research output: Types of Thesis > Doctoral thesis
2002
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A novel dynamic model of hematopoietic stem cell organization based on the concept of within-tissue plasticity, Aug 2002, In: Experimental hematology. 30, 8, p. 853-61, 9 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Tissue stem cells: Definition, plasticity, heterogeneity, self-organization and models - A conceptual approach, 2002, In: Cells tissues organs. 171, 1, p. 8-26, 19 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
2000
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Cytokeratin-positive cells in bone marrow in comparison with other prognostic factors in colon carcinoma, Aug 2000, In: Langenbeck's archives of surgery. 385, 5, p. 337-343, 7 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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