Prof. Ingo Roeder, Ph.D.
© P.Benjamin/NCTDD
Chair for Medical Biometry and Statistics
NameMr Prof. Dr. rer. med. Ingo Röder
Institute Director
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Prof. Ingo Roeder is Head of the Institute for Medical Informatics and Biometry. He is a member of the Carl Gustav Carus Medical Faculty at the Technische Universität Dresden. In particular, he holds the Chair for Medical Statistics and Biometry. Since 2015 Prof. Roeder has been scientific head of the Core Unit for Data Management and Analytics (DMA) at the National Centre for Tumor Diseases (NCT) at the partner site Dresden. Between 2014 and 2018 he acted as CIO of the TU Dresden School of Medicine. Since 2018 he ihas been dean of studies at the Faculty of Medicine.
Prof. Roeder’s research focus covers the following areas:
Theoretical Biology/System medicine:
- Application of mathematical models in the context of treatment optimisation/model-based experimental/study design (e.g. regarding CML, AML, T-PLL)
- Dynamics of molecular regulation networks
- Theoretical concepts of stem cell organisation (theoretical setm cell biology)
- Clonal competition phenomena and stem cell/niche interactions
Biostatistics/Bioinformatics:
- Statistical modelling (e.g. mixed-effect models)
- Analysis of cellular genealogies
- Analysis of single cell tracking data
- Model-based trial design
- Integrative analysis of molecular data (e.g. NGS-based)
Medical Informatics:
- Data integration models
- „Big Data“ in oncology
- Integration of model predictions in processes of clinical decision-making
Publications
2020
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Survival differences and associated molecular signatures of DNMT3A-mutant acute myeloid leukemia patients, 29 Jul 2020, In: Scientific reports. 10, 1, 12761Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Domain-specific cues improve robustness of deep learning-based segmentation of CT volumes, 1 Jul 2020, In: Scientific reports. 10, 1, p. 10712Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse, 18 Jun 2020, In: Nature communications. 11, 1, 3101Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Model-Based Inference and Classification of Immunologic Control Mechanisms from TKI Cessation and Dose Reduction in Patients with CML, 1 Jun 2020, In: Cancer research. 80, 11, p. 2394-2406, 13 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Urinary MicroRNAs as potential markers for non-invasive diagnosis of bladder cancer, 1 Jun 2020, In: International journal of molecular sciences. 21, 11, 3814Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Identifying Genetic Lesions in Ocular Adnexal Extranodal Marginal Zone Lymphomas of the MALT Subtype by Whole Genome, Whole Exome and Targeted Sequencing, 17 Apr 2020, In: Cancers. 12, 4, 986Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Molecular monitoring during dose reduction predicts recurrence after TKI cessation in CML, 5 Mar 2020, In: Blood. 135, 10, p. 766-769, 4 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Integration of mathematical model predictions into routine workflows to support clinical decision making in haematology, 10 Feb 2020, In: BMC medical informatics and decision making. 20, 1, 28Electronic (full-text) versionResearch output: Contribution to journal > Research article
2019
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Multi-scale imaging and analysis identify pan-embryo cell dynamics of germlayer formation in zebrafish, 17 Dec 2019, In: Nature communications. 10, 1, 5753Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Automated detection of the HER2 gene amplification status in Fluorescence in situ hybridization images for the diagnostics of cancer tissues, 1 Dec 2019, In: Scientific reports. 9, 1, 8231Electronic (full-text) versionResearch output: Contribution to journal > Research article