Prof. Ingo Roeder, Ph.D.
© P.Benjamin/NCTDD
Chair for Medical Biometry and Statistics
NameMr Prof. Dr. rer. med. Ingo Röder
Institute Director
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Prof. Ingo Roeder is Head of the Institute for Medical Informatics and Biometry. He is a member of the Carl Gustav Carus Medical Faculty at the Technische Universität Dresden. In particular, he holds the Chair for Medical Statistics and Biometry. Since 2015 Prof. Roeder has been scientific head of the Core Unit for Data Management and Analytics (DMA) at the National Centre for Tumor Diseases (NCT) at the partner site Dresden. Between 2014 and 2018 he acted as CIO of the TU Dresden School of Medicine. Since 2018 he ihas been dean of studies at the Faculty of Medicine.
Prof. Roeder’s research focus covers the following areas:
Theoretical Biology/System medicine:
- Application of mathematical models in the context of treatment optimisation/model-based experimental/study design (e.g. regarding CML, AML, T-PLL)
- Dynamics of molecular regulation networks
- Theoretical concepts of stem cell organisation (theoretical setm cell biology)
- Clonal competition phenomena and stem cell/niche interactions
Biostatistics/Bioinformatics:
- Statistical modelling (e.g. mixed-effect models)
- Analysis of cellular genealogies
- Analysis of single cell tracking data
- Model-based trial design
- Integrative analysis of molecular data (e.g. NGS-based)
Medical Informatics:
- Data integration models
- „Big Data“ in oncology
- Integration of model predictions in processes of clinical decision-making
Publications
2016
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Process-based approach to modeling recurrent-event data explicated on the basis of occurrences of tooth losses in two different prosthetic treatment concepts, 17 May 2016, In: Trials. 17, 1, 244Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Dissecting mechanisms of mouse embryonic stem cells heterogeneity through a model-based analysis of transcription factor dynamics, Apr 2016, In: Journal of the Royal Society Interface. 13, 117, p. 1-10, 10 p., 20160167Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Mice in an enriched environment learn more flexibly because of adult hippocampal neurogenesis, 1 Feb 2016, In: Hippocampus. 26, 2, p. 261-271, 11 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
2015
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Image-based quantification and mathematical modeling of spatial heterogeneity in ESC colonies, Jun 2015, In: Cytometry : the journal of the International Society for Analytical Cytology. 87, 6, p. 481-490, 10 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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High-throughput monitoring of integration site clonality in preclinical and clinical gene therapy studies, 29 Apr 2015, In: Molecular Therapy Methods and Clinical Development. 2, 14061Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Distinct roles of β-cell mass and function during type 1 diabetes onset and remission., 2015, In: Diabetes. 64, 6, p. 2148-2160, 13 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
2014
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Safety of switching from vitamin K antagonists to dabigatran or rivaroxaban in daily care--results from the Dresden NOAC registry, 1 Oct 2014, In: British Journal of Clinical Pharmacology. 78, 4, p. 908-917, 10 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Elucidating functional heterogeneity in hematopoietic progenitor cells: a combined experimental and modeling approach, Sep 2014, In: Experimental Hematology. 42, 9, p. 826-837.e17, 12 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Multiplexing clonality: combining RGB marking and genetic barcoding, Apr 2014, In: Nucleic Acids Research. 42, 7, 10 p., e56Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Placement makes a difference: Accuracy of an accelerometer in measuring step number and stair climbing, Apr 2014, In: Gait & posture : official journal of Gait and Clinical Movement Analysis Society (GCMAS) and European Society of Movement Analysis in Adults and Children (ESMAC). 39, 4, p. 1126-1132, 7 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article