Prof. Ingo Roeder, Ph.D.
© P.Benjamin/NCTDD
Chair for Medical Biometry and Statistics
NameMr Prof. Dr. rer. med. Ingo Röder
Institute Director
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Prof. Ingo Roeder is Head of the Institute for Medical Informatics and Biometry. He is a member of the Carl Gustav Carus Medical Faculty at the Technische Universität Dresden. In particular, he holds the Chair for Medical Statistics and Biometry. Since 2015 Prof. Roeder has been scientific head of the Core Unit for Data Management and Analytics (DMA) at the National Centre for Tumor Diseases (NCT) at the partner site Dresden. Between 2014 and 2018 he acted as CIO of the TU Dresden School of Medicine. Since 2018 he ihas been dean of studies at the Faculty of Medicine.
Prof. Roeder’s research focus covers the following areas:
Theoretical Biology/System medicine:
- Application of mathematical models in the context of treatment optimisation/model-based experimental/study design (e.g. regarding CML, AML, T-PLL)
- Dynamics of molecular regulation networks
- Theoretical concepts of stem cell organisation (theoretical setm cell biology)
- Clonal competition phenomena and stem cell/niche interactions
Biostatistics/Bioinformatics:
- Statistical modelling (e.g. mixed-effect models)
- Analysis of cellular genealogies
- Analysis of single cell tracking data
- Model-based trial design
- Integrative analysis of molecular data (e.g. NGS-based)
Medical Informatics:
- Data integration models
- „Big Data“ in oncology
- Integration of model predictions in processes of clinical decision-making
Publications
2011
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Towards a quantitative understanding of stem cell-niche interaction: experiments, models, and technologies, 15 Apr 2011, In: Blood cells, molecules & diseases : BCMD. 46, 4, p. 308-17, 10 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
2010
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Nanog variability and pluripotency regulation of embryonic stem cells--insights from a mathematical model analysis, 21 Jun 2010, In: PLoS ONE. 5, 6, p. e11238Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Towards a Cellular Genealogy Ontology, 2010, 2nd Workshop of the GI-Fachgruppe "Ontologien in Biomedizin und Lebenswissenschaften (OBML)", 09-10. September 2010 in Mannheim. Universität LeipzigElectronic (full-text) versionResearch output: Contribution to book/conference proceedings/anthology/report > Chapter in book/Anthology/Report
2009
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Stem cell biology meets systems biology, Nov 2009, In: Development (Cambridge, England). 136, 21, p. 3525-30, 6 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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QuickMap: a public tool for large-scale gene therapy vector insertion site mapping and analysis, Jul 2009, In: Gene therapy. 16, 7, p. 885-93, 9 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Stem cell proliferation and quiescence--two sides of the same coin, Jul 2009, In: PLOS computational biology. 5, 7, e1000447Electronic (full-text) versionResearch output: Contribution to journal > Research article
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An "age"-structured model of hematopoietic stem cell organization with application to chronic myeloid leukemia, Apr 2009, In: Bulletin of mathematical biology. 71, 3, p. 602–626, 25 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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A novel view on stem cell development: Analysing the shape of cellular genealogies, Apr 2009, In: Cell Proliferation. 42, 2, p. 248-263, 16 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Agent-Based Modeling of Stem Cells, 2009, Multi-Agent Systems: Simulation and Applications. CRC Press - Taylor & Francis Group, p. 389–421Electronic (full-text) versionResearch output: Contribution to book/conference proceedings/anthology/report > Chapter in book/Anthology/Report
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Model-Based Analysis of Stem Cell Dynamics - An Application of Medical Systems Biology, 2009Research output: Types of Thesis > Habilitation thesis
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