Prof. Ingo Roeder, Ph.D.
© P.Benjamin/NCTDD
Chair for Medical Biometry and Statistics
NameMr Prof. Dr. rer. med. Ingo Röder
Institute Director
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Prof. Ingo Roeder is Head of the Institute for Medical Informatics and Biometry. He is a member of the Carl Gustav Carus Medical Faculty at the Technische Universität Dresden. In particular, he holds the Chair for Medical Statistics and Biometry. Since 2015 Prof. Roeder has been scientific head of the Core Unit for Data Management and Analytics (DMA) at the National Centre for Tumor Diseases (NCT) at the partner site Dresden. Between 2014 and 2018 he acted as CIO of the TU Dresden School of Medicine. Since 2018 he ihas been dean of studies at the Faculty of Medicine.
Prof. Roeder’s research focus covers the following areas:
Theoretical Biology/System medicine:
- Application of mathematical models in the context of treatment optimisation/model-based experimental/study design (e.g. regarding CML, AML, T-PLL)
- Dynamics of molecular regulation networks
- Theoretical concepts of stem cell organisation (theoretical setm cell biology)
- Clonal competition phenomena and stem cell/niche interactions
Biostatistics/Bioinformatics:
- Statistical modelling (e.g. mixed-effect models)
- Analysis of cellular genealogies
- Analysis of single cell tracking data
- Model-based trial design
- Integrative analysis of molecular data (e.g. NGS-based)
Medical Informatics:
- Data integration models
- „Big Data“ in oncology
- Integration of model predictions in processes of clinical decision-making
Publications
2009
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New experimental and theoretical investigations of hematopoietic stem cells and chronic myeloid leukemia, 2009, In: Blood cells, molecules & diseases : BCMD. 43, 1, p. 88-97, 10 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Vergleichende Untersuchungen zur Tenazität verschiedener Modellviren gegenüber chemischen Desinfektionsmitteln, 2009, In: Hygiene & Medizin. 34, 6, p. 224 - 232Research output: Contribution to journal > Research article
2008
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Characterization and quantification of clonal heterogeneity among hematopoietic stem cells: a model-based approach, 15 Dec 2008, In: Blood. 112, 13, p. 4874-83, 10 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Insertional mutagenesis and clonal dominance: biological and statistical considerations, Jan 2008, In: Gene therapy. 15, 2, p. 143–153, 11 p.Electronic (full-text) versionResearch output: Contribution to journal > Review article
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Pathogenesis, treatment effects, and resistance dynamics in chronic myeloid leukemia--insights from mathematical model analyses, Jan 2008, In: Journal of Molecular Medicine. 86, 1, p. 17-27, 11 p.Electronic (full-text) versionResearch output: Contribution to journal > Review article
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Correlation patterns of cellular genealogies, 2008, Fifth International Workshop on Computational Systems Biology (WCSB), June 11–13 2008. p. 161-164Research output: Contribution to book/conference proceedings/anthology/report > Conference contribution
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Mathematical modeling of genesis and treatment of chronic myeloid leukemia, 2008, In: Cells tissues organs : in vivo, in vitro ; CTO. 188, 1-2, p. 236-247, 12 p.Electronic (full-text) versionResearch output: Contribution to journal > Review article
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Tracking of hematopoietic stem cell adhesion and proliferation in artificial microenvironments, 2008, 8th World Biomaterials Congress 2008Research output: Contribution to book/conference proceedings/anthology/report > Conference contribution
2007
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No evidence of clonal dominance in primates up to 4 years following transplantation of multidrug resistance 1 retrovirally transduced long-term repopulating cells, Oct 2007, In: Stem cells (Dayton, Ohio). 25, 10, p. 2610–2618, 9 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article
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Lineage specification of hematopoietic stem cells: mathematical modeling and biological implications, Jul 2007, In: Stem cells (Dayton, Ohio). 25, 7, p. 1791-9, 9 p.Electronic (full-text) versionResearch output: Contribution to journal > Research article